mvstaller.bsky.social
@mvstaller.bsky.social
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mvstaller.bsky.social
mvstaller.bsky.social @mvstaller.bsky.social · Jan 10
Happy new year! Our new preprint is live! We use single molecule imaging in live cells to show that activation domains can control how transcription factors bind to chromatin. SMT 1 TF Dogma 0 www.biorxiv.org/content/10.1...
Short activation domains control chromatin association of transcription factors
Transcription factors regulate gene expression with DNA-binding domains (DBDs) and activation domains. It is generally assumed that DBDs are solely responsible for interacting with DNA and chromatin. ...
www.biorxiv.org
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mvstaller.bsky.social
mvstaller.bsky.social @mvstaller.bsky.social · Dec 10
Our new preprint went live on biorxiv. We show: 1) conservation of function without conservation of sequence for a transcription factor over 600 million years of evolution. 2) The key​ phenylalanine residues turnover​, moving around. www.biorxiv.org/content/10.1...
www.biorxiv.org
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