Nathan Hawkins
@nathhawkins.bsky.social
800 followers 2.2K following 190 posts
CEO Spectrometrics Limited Innovator, Chromatography, Mass Spectrometry, Lab Automation, Software & Spectral Libraries
Posts Media Videos Starter Packs
nathhawkins.bsky.social
Just discovered you can recycle blister packs at Boots pharmacies. Wonder if they take blister packs from GC consumables (ferrules, inlet liners, o-rings, etc) too?
I already the PET containers some vendors use in the household recycling.
www.boots.com/shopping/boo...
Blister Pack Recycling | Recycle at Boots Scheme
Recycle your empty blister packs in-store and earn Advantage Card points when you spend £5 at participating stores. Terms and conditions apply.
www.boots.com
nathhawkins.bsky.social
Does your GC/GC-MS have a lonely heart and yearn for a PAL-xt instead of a boring Agilent ALS.
@pal-system.bsky.social
spectrometrix.bsky.social
🥰 For Sale: Refurbished PAL-xt sampler seeking a new GC-MS soulmate! Fully serviced, ready to inject love into your lab. Reliable, precise, & full of charm.
email: [email protected] for details! 💖
#LabEquipment #GCMS #ScienceLove
GERSTEL branded PAL-xt sampler configured for headspace and liquid injection
nathhawkins.bsky.social
Appreciate that it’s a long shot but does anyone have a Sigma SPME/HPLC interface (57350-U) in a drawer somewhere that they could donate to an R&D project.
nathhawkins.bsky.social
Get to the train early and it’s running 20minutes late (glad I accounted for potentially delayed DB service when I booked).
nathhawkins.bsky.social
When I first fully automated metabolomics MOX-TMS sample prep in 2007/2008, the main driver was data quality. Improved productivity, sustainability and effective use of person resource were secondary (to us), but secured the grant funding from BBSRC. @ukri.org
ROI: 2x CapEx costs, 10x OpEx savings
a robot says hi rajarshi here in yellow
Alt: a black and white humanoid robot waving
media.tenor.com
nathhawkins.bsky.social
The same can’t be said of the T3 version
Stretched red VW T3 minibus with additional panel in front of sliding side door
nathhawkins.bsky.social
I think the proportions on this may actually be an improvement on the original
Stretched VW T2 bay window camper with additional panel in front of sliding door
nathhawkins.bsky.social
In my experience:
• there are things that won’t work
• and things that didn’t work because old chemists didn’t understand why they didn’t work and/or the technology has developed so they now will
Wisdom is to know the difference
nathhawkins.bsky.social
No problem with standard abbreviation. The issue is using non-standard ambiguous abbreviation that is a safety risk (in my career, I’ve seen enough incidents and near misses caused by unambiguous abbreviations).
MeCN is unambiguous (albeit legacy), CH3CN is preferred (IUPAC blue book).
nathhawkins.bsky.social
For most analytical derivatization, I’d rather take the time to validate a methyl iodide based method.
nathhawkins.bsky.social
In this case the reference book was written before the toxicity was understood…
nathhawkins.bsky.social
Wikipedia article for TMS diazomethane says it’s safer than diazomethane - when I did the risk assessment we estimated that it was at least 3-4 orders of magnitude more toxic than diazomethane, toxic by all routes of administration and probably permeates nitrile gloves #ChemSky
two men in yellow coveralls are standing next to each other with the words let 's cook written on the bottom
Alt: two men in yellow coveralls are standing next to each other with the words let 's cook written on the bottom
media.tenor.com
nathhawkins.bsky.social
With budgets hard to secure, upgrading your existing instrument can be an affordable and sustainable way to add to your labs capabilities.
And you can catch me at #BMSS25 next month to learn more.
spectrometrix.bsky.social
Did you know you can upgrade your existing Agilent MSD to a triple quad for a fraction of the price of a 7000E. You can even upgrade a diff pump system!
[email protected]
#sustainability #greenchemistry
Agilent 5977A MSD with Evolution QQQ upgrade
nathhawkins.bsky.social
100 mL anhydrous for derivatization - the acetonitrile was obvious when the MOX didn’t dissolve. The pyridine was just obvious!
nathhawkins.bsky.social
Really big, very well established one
nathhawkins.bsky.social
Only when what’s on the label is what’s in the bottle. I’ve had vendor mislabelling: bottle of acetonitrile turned out to be pyridine (and on a separate occasion the reverse). Also had nitrogen in a helium cylinder (28 on the MS tune was a ‘bit’ high).
nathhawkins.bsky.social
The random bottle simply labelled ether (it’s probably going to be petroleum or diethyl) - “what do you mean the days when you couldn’t get a degree without knowing the top 10 organic solvents (including benzene and carbon tetrachloride) by smell are over”.
Similarly alcohol…
nathhawkins.bsky.social
Anyone else have a particular bugbear about the use of ambiguous abbreviations in the organic and biochemistry lab.
ACN: one person’s acrylonitrile is another one’s acetonitrile
IAA: iodoacetamide or auxin?
I’ve seen enough near-misses through ambiguous labelling to last a lifetime.
#ChemSky
nathhawkins.bsky.social
Looking forward to the 45th BMSS meeting next month.
@bmss-official.bsky.social
Photo of Edinburgh International Conference Centre against a blue sky
Reposted by Nathan Hawkins
spectrometrix.bsky.social
Calling #TeamMetabolomics UK - Spectrometrics has 3 #Metabolomics PrepStations in stock to automate the Fiehn MOX-TMS Protocol. Great for teaching metabolomics or for early career researchers wanting to automate GC-MS metabolomics.
@scotmetnet.bsky.social @emn-metsoc.bsky.social @lbmsdg.bsky.social
spectrometrix.bsky.social
Did you know you can miss (less stable) metabolites, or their derivatives with batch prep? They’re filtered out in your preprocessing. Just-in-time metabolomics preserves them, boosting feature retention & biomarker discovery.
#Metabolomics #ScienceTips #PrepAhead
[email protected]
Metabolomics prep-station (rail based sampler with trays, wash stations and incubators) for just-in-time MOX-TMS GC-MS Metabolomics
nathhawkins.bsky.social
Will get round to installing VMs on my desktop and laptop - needed to establish how far I needed to roll-back to make them work. Think MassTransit stopped working when I upgraded from Windows 10 to 11.