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Reposted by Nott Lab
Alex Holehouse
@alexholehouse.bsky.social
· May 23
Nott Lab
@nottlab.bsky.social
· Mar 17
Intrinsic hydrophobicity of IDP-based biomolecular condensates drives their partial drying on membrane surfaces
The localization of biomolecular condensates to intracellular membrane surfaces has emerged as an important feature of sub-cellular organization. In this work,
doi.org
Nott Lab
@nottlab.bsky.social
· Mar 5
Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
Cells chemically isolate molecules in compartments to both facilitate and regulate their interactions. In addition to membrane-encapsulated compartmen…
www.sciencedirect.com
Reposted by Nott Lab
Reposted by Nott Lab
Alex Holehouse
@alexholehouse.bsky.social
· Jan 17
Molecular determinants of condensate composition
Biomolecular condensates are non-stochiometric assemblies that organize cellular matter
in space and time. Despite much work, many questions remain regarding what determines
the recruitment and exclus...
www.cell.com
Reposted by Nott Lab
Reposted by Nott Lab