Nicola Zamboni
@nzamboni.bsky.social
sysbio, metabolism, metabolomics #ETH Zurich.
Free thoughts on metabolomics.blog
Free thoughts on metabolomics.blog
Reposted by Nicola Zamboni
Amazing dataset describing the metabolic profiles of 66 E. coli transporter knockouts by @sulheim.bsky.social with Peter Doubleday and @nzamboni.bsky.social. The tool, set up by @lambdapp.bsky.social and Eric Ulrich allows you to explore for yourself. Enjoy! Pre-print here: doi.org/10.1101/2025...
December 3, 2025 at 1:11 PM
Amazing dataset describing the metabolic profiles of 66 E. coli transporter knockouts by @sulheim.bsky.social with Peter Doubleday and @nzamboni.bsky.social. The tool, set up by @lambdapp.bsky.social and Eric Ulrich allows you to explore for yourself. Enjoy! Pre-print here: doi.org/10.1101/2025...
Reposted by Nicola Zamboni
This project wouldn't been possible without Peter Doubleday and @nzamboni.bsky.social at @imsb-eth.bsky.social. Peter conducted >10,000 mass spec analyses 🤯. So grateful for this opportunity to team up with the best of the best in metabolomics 😍
Read more: www.biorxiv.org/content/10.1...
#microsky
Read more: www.biorxiv.org/content/10.1...
#microsky
Do you think transporters in E. coli contribute to metabolite release? No? Explore the effect of 66 different transporter knockout mutations on the exometabolome dynamics of ~300 metabolites yourself: keio.unil.ch
Teaser: Increased proline in ΔputP
#microsky #MEvoSky
Teaser: Increased proline in ΔputP
#microsky #MEvoSky
December 3, 2025 at 12:50 PM
This project wouldn't been possible without Peter Doubleday and @nzamboni.bsky.social at @imsb-eth.bsky.social. Peter conducted >10,000 mass spec analyses 🤯. So grateful for this opportunity to team up with the best of the best in metabolomics 😍
Read more: www.biorxiv.org/content/10.1...
#microsky
Read more: www.biorxiv.org/content/10.1...
#microsky
Reposted by Nicola Zamboni
In the latest issue of Analyst:
Optimisation of electron-induced dissociation parameters for molecular annotation of glycerides and phospholipids in fast LC-MS.
#OpenAccess from Nicola Zamboni et al @nzamboni.bsky.social @alaaothman.bsky.social @ethz.ch Read now: pubs.rsc.org/en/content/a...
Optimisation of electron-induced dissociation parameters for molecular annotation of glycerides and phospholipids in fast LC-MS.
#OpenAccess from Nicola Zamboni et al @nzamboni.bsky.social @alaaothman.bsky.social @ethz.ch Read now: pubs.rsc.org/en/content/a...
Optimisation of electron-induced dissociation parameters for molecular annotation of glycerides and phospholipids in fast LC-MS
Electron-induced dissociation methods, particularly electron impact excitation of ions from organics (EIEIO), offer enhanced capabilities for lipid structural elucidation over traditional collision-in...
pubs.rsc.org
November 19, 2025 at 9:09 AM
In the latest issue of Analyst:
Optimisation of electron-induced dissociation parameters for molecular annotation of glycerides and phospholipids in fast LC-MS.
#OpenAccess from Nicola Zamboni et al @nzamboni.bsky.social @alaaothman.bsky.social @ethz.ch Read now: pubs.rsc.org/en/content/a...
Optimisation of electron-induced dissociation parameters for molecular annotation of glycerides and phospholipids in fast LC-MS.
#OpenAccess from Nicola Zamboni et al @nzamboni.bsky.social @alaaothman.bsky.social @ethz.ch Read now: pubs.rsc.org/en/content/a...
Reposted by Nicola Zamboni
Available to read now via Open Access:
pubs.rsc.org/en/content/a...
Fast, general-purpose metabolome analysis by mixed-mode liquid chromatography–mass spectrometry
Nicola Zamboni et al @nzamboni.bsky.social @alaaothman.bsky.social @ethz.ch
#MassSpec
pubs.rsc.org/en/content/a...
Fast, general-purpose metabolome analysis by mixed-mode liquid chromatography–mass spectrometry
Nicola Zamboni et al @nzamboni.bsky.social @alaaothman.bsky.social @ethz.ch
#MassSpec
October 30, 2025 at 9:28 AM
Available to read now via Open Access:
pubs.rsc.org/en/content/a...
Fast, general-purpose metabolome analysis by mixed-mode liquid chromatography–mass spectrometry
Nicola Zamboni et al @nzamboni.bsky.social @alaaothman.bsky.social @ethz.ch
#MassSpec
pubs.rsc.org/en/content/a...
Fast, general-purpose metabolome analysis by mixed-mode liquid chromatography–mass spectrometry
Nicola Zamboni et al @nzamboni.bsky.social @alaaothman.bsky.social @ethz.ch
#MassSpec
Reposted by Nicola Zamboni
We are beyond happy to see so many contributions from the #SIRIUScommunity at tat #Metabolomics2025. Don't miss the opportunity to get in touch and gain first-hand insights how you can integrate SIRIUS into your annotation workflow.
June 23, 2025 at 1:08 PM
We are beyond happy to see so many contributions from the #SIRIUScommunity at tat #Metabolomics2025. Don't miss the opportunity to get in touch and gain first-hand insights how you can integrate SIRIUS into your annotation workflow.
I've been asked about my slides on the #ZenoTOF8600. We uploaded the poster, which includes the data and comments, plus all key data and results at polybox.ethz.ch/index.php/s/.... Feel free to reshare or to ping me for more.
8600_data
polybox - Use it as a logical memory stick, store your data on the ETH campus!
polybox.ethz.ch
June 3, 2025 at 10:48 PM
I've been asked about my slides on the #ZenoTOF8600. We uploaded the poster, which includes the data and comments, plus all key data and results at polybox.ethz.ch/index.php/s/.... Feel free to reshare or to ping me for more.
This was funny until I realized I am the one who has to prove it. 👀👀
For a discovery to be extraordinary, the proof must be, too.
Join us at #ASMS2025. Skeptics welcome 👉 sciex.li/1pw179
youtu.be/vnOJN_rAakw
Join us at #ASMS2025. Skeptics welcome 👉 sciex.li/1pw179
youtu.be/vnOJN_rAakw
For a discovery to be extraordinary, the proof must be too - ASMS2025
YouTube video by SCIEX
youtu.be
May 20, 2025 at 3:08 PM
This was funny until I realized I am the one who has to prove it. 👀👀
Reposted by Nicola Zamboni
Reposted by Nicola Zamboni
A study using an n=1 experiment with single standards at 0V CID reported that 70% of detected ions were in-source fragments (ISFs). www.nature.com/articles/s42... This finding was extrapolated to suggest that ISFs affect all metabolomics experiments to this degree. A counterpoint. rdcu.be/ebFwc 1/n
March 3, 2025 at 8:25 PM
A study using an n=1 experiment with single standards at 0V CID reported that 70% of detected ions were in-source fragments (ISFs). www.nature.com/articles/s42... This finding was extrapolated to suggest that ISFs affect all metabolomics experiments to this degree. A counterpoint. rdcu.be/ebFwc 1/n
Reposted by Nicola Zamboni
I'm happy to share a correspondence in @naturemetabolism.bsky.social in which I was involved. #metabolomics #lipidomics www.nature.com/articles/s42...
Discovery of metabolites prevails amid in-source fragmentation - Nature Metabolism
Nature Metabolism - Discovery of metabolites prevails amid in-source fragmentation
www.nature.com
February 28, 2025 at 10:10 AM
I'm happy to share a correspondence in @naturemetabolism.bsky.social in which I was involved. #metabolomics #lipidomics www.nature.com/articles/s42...