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Oncology Clinical Trials Office @octooxford.bsky.social · 4h

The MILI trial aims to determine whether a medication called metformin will reduce the chance of developing cancer in people with LFS.

To learn more about the MILI trial and LFS, visit mili.octru.ox.ac.uk and The George Pantziarka TP53 Trust: tp53.co.uk/lfs-tp53/

Oncology Clinical Trials Office @octooxford.bsky.social · Jul 30

The MILI site team based in Leicester Royal Infirmary share why working with clinical trials is important to them.
Find out more about MILI here: mili.octru.ox.ac.uk

#LFS #TP53 #LiFraumeniSyndrome #LeicesterRoyalInfirmary

Oncology Clinical Trials Office @octooxford.bsky.social · Jul 24

The MILI site team based at Aberdeen Royal Infirmary share what this study means to them.
Find out more about MILI here: mili.octru.ox.ac.uk
#LFS #TP53 #LiFraumeniSyndrome @NHSGrampian

A quotation from a Research Nurse at Aberdeen Royal Infirmary working on the MILI trial says, "The possibility of discovering medication that will reduce the incidence of cancer is exciting and will change the lives of many patients living with the condition".

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Oncology Clinical Trials Office @octooxford.bsky.social · Jul 17

‘The GPTP53 trust have published some more information about the MILI trial.

Visit their website to find out more: www.tp53.org.uk/mili-trial-f...

#LFS #LiFraumeniSyndrome

@oncology.ox.ac.uk @oxfordcancer.bsky.social

MILI Trial – FAQs

Frequently Asked Questions for the MILI Trial Eligibility and trial participation My whole-body MRI scan is more than 3 months old, can I still be enrolled into the trial? No, however if may be pos…

www.tp53.org.uk

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Oncology Clinical Trials Office @octooxford.bsky.social · Jul 2

The MILI site team based in Leicester Royal Infirmary speak on what this study means to them.

Find out more about MILI here: mili.octru.ox.ac.uk

#LFS #TP53 #LiFraumeniSyndrome

Oncology Clinical Trials Office @octooxford.bsky.social · Jun 25

Members of the MILI Trial team are attending the 2025 CRUK Cancer Prevention Research Conference this week.

@cancerresearchuk.org @oxfordcancer.bsky.social
#CRUK #LFS

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Oncology Clinical Trials Office @octooxford.bsky.social · May 12

#InternationalNursesDay
#InternationalNursesDay2025

Oncology Clinical Trials Office @octooxford.bsky.social · May 12

To all the research nurses working on the SCOOT trial.

Thank you for all that you do!

#InternationalNursesDay
#InternationalNursesDay2025

Oncology Clinical Trials Office @octooxford.bsky.social · May 12

To all the research nurses working on the MILI trial!

@ouhospitals.bsky.social
@gstt-nhs.bsky.social
@cuh.nhs.uk
@nhsgrampian.bsky.social
@uhsft.bsky.social
@leicestersresearch.bsky.social
@nottmhospitals.bsky.social

#InternationalNursesDay
#LFS
#TP53

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Oncology Clinical Trials Office @octooxford.bsky.social · May 12

To all the research nurses working on the TebeMRD trial.

#InternationalNursesDay #InternationalNursesDay2025

Oncology Clinical Trials Office @octooxford.bsky.social · May 12

On #InternationalNursesDay...

Oncology Clinical Trials Office @octooxford.bsky.social · May 8

Thank you to all our recruiting sites for your support of the trial:

@ouhospitals.bsky.social
@gstt-nhs.bsky.social
@cuh.nhs.uk
@nhsgrampian.bsky.social
@uhsft.bsky.social
@leicestersresearch.bsky.social h.bsky.social

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Oncology Clinical Trials Office @octooxford.bsky.social · May 8

A MILI Milestone:

30 participants randomised onto the trial!

#TP53 #LiFraumeniSyndrome #LFS

@oncology.ox.ac.uk
@oxfordcancer.bsky.social
The George Pantziarka TP53 Trust

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Oncology Clinical Trials Office @octooxford.bsky.social · Mar 20

What is LFS? A person with LFS carries a pathogenetic variant in their TP53 gene associated with an increased risk of cancer. To find out more about LFS and current research, including the MILI clinical trial:
MILI tinyurl.com/nu3w4ba3
TP53 Trust tinyurl.com/yufxf4um
#LFS @oxfordcancer.bsky.social

Oncology Clinical Trials Office @octooxford.bsky.social · Mar 12

The MILI trial is pleased to announce that our 7th site, University Hospitals of Leicester NHS Trust, is now open to recruitment!

#TP53 #LiFraumeniSyndrome #LFS

@leicestersresearch.bsky.social
@oxfordcancer.bsky.social
@oncology.ox.ac.uk

Oncology Clinical Trials Office @octooxford.bsky.social · Mar 11

The MILI trial is pleased to announce that our 6th site, University Hospital Southampton NHS Foundation Trust, is now open to recruitment!

@uhsft.bsky.social
@oxfordcancer.bsky.social
@oncology.ox.ac.uk

#TP53 #LiFraumeniSyndrome #LFS

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Oncology Clinical Trials Office @octooxford.bsky.social · Feb 19

MILI Participants, we want to hear from you!

#TP53 #LiFraumeniSyndrome #LFS #OxfordCancer #rarediseases

@oxfordcancer.bsky.social @oncology.ox.ac.uk @ouhospitals.bsky.social @cuhnhs.bsky.social @nottmhospitals.bsky.social @nhsgrampian.bsky.social
@gstt-nhs.bsky.social

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Oncology Clinical Trials Office @octooxford.bsky.social · Feb 12

....visit The George Pantziarka TP53 Trust article on randomisation in the MILI Trial to find out more:

tp53.co.uk/2024/08/13/w...

#LFS #TP53

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Why Is MILI Randomised?

The MILI trial is designed to test whether metformin, a drug that treats type II diabetes, can reduce the risk of cancer in people with Li Fraumeni Syndrome (LFS). The truth is that we don’t know i…

tp53.co.uk

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Oncology Clinical Trials Office @octooxford.bsky.social · Feb 12

The full title of the MILI trial is "Metformin in Li Fraumeni Syndrome Trial: A phase II randomised open-label cancer prevention trial of metformin in adults with Li Fraumeni Syndrome".

But what does "randomised" mean, and why is it done...
(1/2)

@oxfordcancer.bsky.social
@oncology.ox.ac.uk

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Oncology Clinical Trials Office @octooxford.bsky.social · Feb 4

#WorldCancerDay #UnitedByUnique

@oncology.ox.ac.uk @oxfordcancer.bsky.social @octructu.bsky.social

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Oncology Clinical Trials Office @octooxford.bsky.social · Feb 4

#WorldCancerDay #UnitedByUnique

TebeMRD Trial website: tebemrd.octru.ox.ac.uk

Oncology Clinical Trials Office @octooxford.bsky.social · Feb 4

#WorldCancerDay #UnitedByUnique

@oncology.ox.ac.uk @oxfordcancer.bsky.social

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Oncology Clinical Trials Office @octooxford.bsky.social · Feb 4

SCOOT is a study aiming to use blood biomarkers to help diagnose lung cancer more accurately and quickly than we can now.

Find out more about SCOOT here:

tinyurl.com/SCOOT-OCTO

#worldcancerday #unitedbyunique #earlydetection

@oncology.ox.ac.uk @oxfordcancer.bsky.social @octructu.bsky.social

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Oncology Clinical Trials Office @octooxford.bsky.social · Feb 4

#WorldCancerDay #UnitedByUnique

@oncology.ox.ac.uk @oxfordcancer.bsky.social

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Oncology Clinical Trials Office @octooxford.bsky.social · Feb 4

To learn more about MILI and Li Fraumeni Syndrome, visit:

mili.octru.ox.ac.uk

and

LFS / TP53 – The George Pantziarka TP53 Trust: tp53.co.uk/lfs-tp53/

#LFS #WorldCancerDay #unitedbyunique

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Welcome to the MILI Trial | MILI

mili.octru.ox.ac.uk

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