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quantifoil.bsky.social
Quantifoil
@quantifoil.bsky.social
We focus on the small stuff so you can too: enabling the resolution revolution with high quality support films for cryo-electron microscopy. Part of
@SPTLabtech.bsky.social
Reposted by Quantifoil
and the Core Facility for Integrated Microscopy – CFIM – funded by @novo-nordisk.bsky.social where we collected our cryo-EM data on the first batch of newly developed HexAuFoil grids from @quantifoil.bsky.social
March 29, 2025 at 2:12 PM
Reposted by Quantifoil
6) We were able to achieve these structures using our newly developed (an)aerobic freezing protocol using the SPT chameleon. This allowed us to generate high quality girds with thin ice without having to be in an anaerobic chamber!
www.biorxiv.org/content/10.1...
January 8, 2025 at 11:08 PM
Reposted by Quantifoil
This work is just our latest saga of tackling the complexities of the small heat shock proteins, following on our recent work with the human aB-crystallin that was just published: www.nature.com/articles/s41...
Dynamic fibrillar assembly of αB-crystallin induced by perturbation of the conserved NT-IXI motif resolved by cryo-EM - Nature Communications
Here the authors show that mutating αB-crystallin’s NT-IXI motif transforms polydispersed oligomers into ordered fibrils, enabling cryo-EM to provide insights into the principles of high-order assembl...
www.nature.com
December 6, 2024 at 4:49 PM
Because after the close of the competition, along came Christelle AlJamous from the IGF in Montpellier
with a stunning 15 sec entry, missing the prize but gaining the bragging rights! Incredible #cryoEM
tweezer skills all round! (and one last pic of the beauty of Carry-le-Rouet).
November 29, 2024 at 5:36 PM
We had a run off competition - from which Nejma Rabhi of the IECB in Bordeaux emerged triumphant, beating her own time with an amazing 18 sec run, and taking away the prize. But wait for the twist...
November 29, 2024 at 5:36 PM
And as the sun set on the final day we had FOUR possible winners tied on 19 secs each: Guillaume Bossan from IBPC, Julie Couston from IRIM in Montpelier, and Pierre Maisonneuve and Nejma Rabhi, both from IECB in Bordeaux! Astonishing scenes - less than 0.5 secs between them and so...
November 29, 2024 at 5:36 PM