rasilab.bsky.social
Subramaniam Lab
@rasilab.bsky.social
26 followers 55 following 2 posts
We study mRNA translation
Posts Media Videos Starter Packs
Pinned
rasilab.bsky.social
Subramaniam Lab @rasilab.bsky.social · May 29
Our RNA-linked CRISPR approach is now published! Work led by fantastic graduate student in the lab, Patrick Nugent.
natmethods.nature.com
Nature Methods @natmethods.nature.com · May 29
ReLiC is an RNA-linked CRISPR platform for dissecting RNA metabolic processes, revealing key regulators of RNA splicing, translation and decay. @rasilab.bsky.social

www.nature.com/articles/s41...
1 2
rasilab.bsky.social
Subramaniam Lab @rasilab.bsky.social · May 29
Our RNA-linked CRISPR approach is now published! Work led by fantastic graduate student in the lab, Patrick Nugent.
natmethods.nature.com
Nature Methods @natmethods.nature.com · May 29
ReLiC is an RNA-linked CRISPR platform for dissecting RNA metabolic processes, revealing key regulators of RNA splicing, translation and decay. @rasilab.bsky.social

www.nature.com/articles/s41...
1 2
rasilab.bsky.social
Subramaniam Lab @rasilab.bsky.social · May 2
Excited to share the work of postdoc Rachael Bakker in collaboration with @lapointelab.bsky.social!

We show that RNA base editors can be repurposed for deep mutational scanning of RNA-RBP interactions at scale both in vitro and in vivo.

www.biorxiv.org/content/10.1...
Deaminase-based RNA recording enables high throughput mutational profiling of protein-RNA interactions
Protein-RNA interactions govern nearly every aspect of RNA metabolism and are frequently dysregulated in disease. While individual protein residues and RNA nucleotides critical for these interactions ...
www.biorxiv.org
3 8