Rick Lanman
@ricklanman.bsky.social
28 followers 23 following 130 posts
Interests are historical ecology (mostly California), cancer, genomics, CoViD, and genealogy.
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ricklanman.bsky.social
Respiratory infections like CoViD & flu awaken metastatic breast cancer lesions so they start growing rapidly. Wearing a mask in crowded places like airports, church, buses makes good sense - remember the main reason to mask is to protect the vulnerable from ourselves www.nature.com/articles/s41...
Respiratory viral infections awaken metastatic breast cancer cells in lungs - Nature
Mouse models show that respiratory infections from viruses such as influenza and SARS-CoV-2 can trigger metastasis of dormant breast cancer cells in the lungs, a finding supported by epidemiological d...
www.nature.com
ricklanman.bsky.social
Cannabis Use Disorder associated with a tripling of oral cancer in 5-year study at six Univ. of California academic centers. Smoking cannabis or tobacco similarly damage the mouth's lining. Not all that new - just strongly confirms the earlier reports of risk. www.sciencedirect.com/science/arti...
Cannabis use disorder and five-year risk of oral cancer in a multicenter clinical cohort
Cannabis use disorder (CUD) is increasingly prevalent in the United States, yet long-term health consequences remain poorly defined. Oral cancer is pl…
www.sciencedirect.com
ricklanman.bsky.social
Also no association with about 50 other disorders including including asthma, allergies, autoimmune conditions, & other neurodevelopmental disorders.
ricklanman.bsky.social
It is also well known that a more acidic vaginal environment favors X chromosome survival. The study found that after 1 boy there is 57% odds of a 2nd boy, and after 1 girl there is a 53% chance of having another girl. Odds increase with two boys or two girls, etc. Not random.
ricklanman.bsky.social
Boy or girl? Study of 58K women with ≥ 2 singleton births found gender of babies is not a coin toss. Women have SNPs (benign mutations) which push towards female-only (NSUN6 gene) vs. male-only (TSHZ1 gene) offspring. www.science.org/doi/10.1126/...
Is sex at birth a biological coin toss? Insights from a longitudinal and GWAS analysis
Offspring sex may not be random—maternal age and genetics influence sex clustering within families.
www.science.org
ricklanman.bsky.social
When the first atomic bomb was developed in the United States, uranium was refined in St. Louis, Missouri, and following the Manhattan Project, radioactive waste was stored in a rural area north of St. Louis.
ricklanman.bsky.social
So tragic. Children living downstream from nuclear waste storage site on Coldwater Creek near St. Louis, had 5x greater risk of thyroid cancer. All the radiation-sensitive cancers (thyroid, breast, leukemia, basal cell skin cancer) were increased. jamanetwork.com/journals/jam...
Cancer Incidence and Childhood Residence Near a Radioactive Waste Site
This cohort study examines the association between living near Coldwater Creek, Missouri, as a child and self-report of cancer incidence collected via surveys administered in the St Louis Baby Tooth–L...
jamanetwork.com
ricklanman.bsky.social
The high X-ray dose is one reason I prefer carotid ultrasound to screen for cardiovascular risk of CT scan of the heart and coronary arteries.
ricklanman.bsky.social
CT or "CAT" scans come with some cost. Of the 93 million CT examinations performed in 62 million US patients in 2023 were projected to result in approximately 103,000 future cancers. CT-associated cancers could soon account for 5% of all new cancer diagnoses annually. jamanetwork.com/journals/jam...
Projected Lifetime Cancer Risks From Current Computed Tomography Imaging
This risk model projects how many future cancers in the United States could result from annual computed tomography examinations.
jamanetwork.com
ricklanman.bsky.social
Turns out >50,000 cancer cases could be prevented if our water suppliers were better at removing chromium, arsenic, and nitrates. One to three of these contaminants exceed health standards in 82% of U.S. community water systems. Time to call the water district? www.sciencedirect.com/science/arti...
ricklanman.bsky.social
Randomized controlled trial comparing semaglutide (aka Ozempic & Wegovy) to tirzepatide (aka Zepbound & Mounjaro). Tirzepatide won hands down with 20.2% weight loss and waist down 18.4 cm. vs semaglutide with 13.7% weight loss and waist down 13.0 cm. www.nejm.org/doi/full/10....
Tirzepatide as Compared with Semaglutide for the Treatment of Obesity | NEJM
Tirzepatide and semaglutide are highly effective medications for obesity management. The efficacy and safety of tirzepatide as compared with semaglutide in adults with obesity but without type 2 di...
www.nejm.org
ricklanman.bsky.social
A breathtaking advance in the cancer fight. Instead of removing your T-cells and modifying them to recognize your cancer and re-infusing them - these investigators made a lipid bubble that carries mRNA to your T-cells instructing them to make the anti-cancer targeting antibody or CAR.
Science Magazine - Engineering immunotherapy from within
Harnessing a patient’s own immune cells to combat diseases while leaving healthy cells unharmed, called adoptive immunotherapy, is considered a powerful treatment option.
www.sciencemagazinedigital.org
ricklanman.bsky.social
The Felon's tariffs are driving up US healthcare insurance premiums by 2.2%-3.6% because insurers have to pay for more expensive imported drugs and devices. UnitedHealthcare is notifying state regulators of the premium hikes. www.kff.org/quick-take/t...
Tariffs Are Driving 2026 Health Insurance Premiums Up
President Trump has vowed to impose tariffs on a wide variety of goods from multiple countries. While consumers may expect the price of some imported goods to go up, what may be surprising is that the...
www.kff.org
ricklanman.bsky.social
Everyone needs the Shingrix vaccine x 2 beginning at age 50 because even if you had the chickenpox vaccination it used live attenuated HVZ virus which can awaken and cause shingles later in life.
ricklanman.bsky.social
Shingles is reactivation of the chickenpox virus (Herpes Varicella Zoster (HVZ) virus) in a nerve fiber as your immune defense weakens with time against it (largely because we don't get continued exposure to kids with chickenpox). It awakens in a nerve with blisters and severe pain called shingles.
ricklanman.bsky.social
If you want dementia, then don't get the shingles vaccine. 20% fewer seniors got dementia if they got the shingle vaccine in the UK! Now also shown in the USA. The more potent Shingrix is the shingles (HVZ) vaccine to get starting at age 50 - 2 doses 2 months apart! www.nature.com/articles/s41...
A natural experiment on the effect of herpes zoster vaccination on dementia - Nature
Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of...
www.nature.com
ricklanman.bsky.social
Efficacy & safety data just keeps getting better for vaccines. FDA 1st approved the RSV vaccine in 2023-2024 and 1 year later it was 75% effective against infection, ER visits & hospitalizations in 60+ year olds. The Felon should resign for appointing Brainworm Bobby. jamanetwork.com/journals/jam...
Respiratory Syncytial Virus Vaccine for US Adults Aged 60 Years or Older
This case-control study assesses the safety and effectiveness of vaccines against respiratory syncytial virus (RSV) and the major adverse events among patients aged 60 years or older during the 2023-2...
jamanetwork.com
ricklanman.bsky.social
Young adults ages 40-49 are getting colon cancer at increasing rates. (I suspect microplastics.) This study just showed that testing your stool for iron reduced colon cancer deaths. I'd start screening at age 40 especially if you have a family history of colon cancer. jamanetwork.com/journals/jam...
Long-Term Effectiveness Associated With Fecal Immunochemical Testing for Early-Age Screening
This cohort study evaluates whether initiating fecal immunochemical test screening at age 40 to 49 years, rather than at the currently recommended age of 50 years, reduces colorectal cancer incidence ...
jamanetwork.com
ricklanman.bsky.social
In fact, I just asked openevidence.com if risk of myocarditis is higher from the infection or the vaccine. Answer: 2c-5x higher from CoViD infection. Plus myocarditis from the vaccine generally subsides on its own. It provided several correct references like this! pubmed.ncbi.nlm.nih.gov/35389977/
OpenEvidence
The leading medical information platform.
openevidence.com
ricklanman.bsky.social
OpenEvidence.com has been a game changer for me (a doctor) to find correct medical information. It is free and does not hallucinate/confabulate. Will save you from needing to call the doctor's office 90% of the time. openevidence.com
OpenEvidence
The leading medical information platform.
OpenEvidence.com
ricklanman.bsky.social
The key message in Phillips Payson O'Brien's Atlantic piece is that OUR tanks, planes and ships are defenseless against drones. Ukraine proved it by destroying 1/3 of Russia's Tu-95 bombers. Cost $1m for a few hundred drones destroyed $ multibillion in Russian aircraft. substack.com/redirect/b5f...
Ukraine’s Warning to the World’s Other Military Forces
Expensive planes, tanks, and ships can be destroyed on the cheap.
substack.com