rPeptide
@rpeptide.bsky.social
R&D Starts Here! Recombinant peptides, proteins, antibodies, reagents, and custom services for Alzheimer’s, Parkinson’s, and other neurodegenerative research.
Tau buildup doesn’t just mark disease—it changes how neurons talk. 🧠
Using rPeptide’s Tau-441 PFFs, researchers found Tau aggregates shift brain signaling toward long-term depression, mirroring early Alzheimer’s disruptions.
t.ly/SmJ7G
#Neuroscience #TauProtein #AlzheimersResearch #rPeptide
Using rPeptide’s Tau-441 PFFs, researchers found Tau aggregates shift brain signaling toward long-term depression, mirroring early Alzheimer’s disruptions.
t.ly/SmJ7G
#Neuroscience #TauProtein #AlzheimersResearch #rPeptide
Incubation with tau aggregates increases hippocampal circuit excitability and enhances long-term depression in acute mouse hippocampal slices
Aggregation of the protein tau is a key pathological hallmark of tauopathies such as Alzheimer’s Disease. Tau dissociates from microtubules and diffuses from the axon into the soma-dendritic compartment, where it aggregates firstly into oligomers ...
t.ly
November 12, 2025 at 1:12 PM
Tau buildup doesn’t just mark disease—it changes how neurons talk. 🧠
Using rPeptide’s Tau-441 PFFs, researchers found Tau aggregates shift brain signaling toward long-term depression, mirroring early Alzheimer’s disruptions.
t.ly/SmJ7G
#Neuroscience #TauProtein #AlzheimersResearch #rPeptide
Using rPeptide’s Tau-441 PFFs, researchers found Tau aggregates shift brain signaling toward long-term depression, mirroring early Alzheimer’s disruptions.
t.ly/SmJ7G
#Neuroscience #TauProtein #AlzheimersResearch #rPeptide
Spending time in nature reduces stress hormones and boosts cognitive focus! 🌳✨
#MindfulMoments #BrainHealth #rPeptide
#MindfulMoments #BrainHealth #rPeptide
November 10, 2025 at 5:49 PM
Spending time in nature reduces stress hormones and boosts cognitive focus! 🌳✨
#MindfulMoments #BrainHealth #rPeptide
#MindfulMoments #BrainHealth #rPeptide
Discovery isn’t confined to the lab — it’s a way of seeing the world! 🌍✨
#EverydayScience #ScienceConnectsUs #InspiringMinds #rPeptide
#EverydayScience #ScienceConnectsUs #InspiringMinds #rPeptide
November 7, 2025 at 2:32 PM
Discovery isn’t confined to the lab — it’s a way of seeing the world! 🌍✨
#EverydayScience #ScienceConnectsUs #InspiringMinds #rPeptide
#EverydayScience #ScienceConnectsUs #InspiringMinds #rPeptide
A new study shows Khaya grandifoliola bark extracts can reduce βA 1-42 aggregation and target multiple disease pathways.
rPeptide’s #BetaAmyloid (1-42) was used to track fibrillation, highlighting plant-based promise in neurodegeneration research.
t.ly/nmxNM
#Neuroscience #Research #rPeptide
rPeptide’s #BetaAmyloid (1-42) was used to track fibrillation, highlighting plant-based promise in neurodegeneration research.
t.ly/nmxNM
#Neuroscience #Research #rPeptide
Khaya grandifololia exerts multitarget neuroprotective potential against neurodegenerative disorders: In vitro and in silico studies
Treatment for complex multifactorial neurological disorders may benefit more from multifunctional chemicals. Dysregulation of monoaminergic pathways a…
t.ly
November 5, 2025 at 1:46 PM
A new study shows Khaya grandifoliola bark extracts can reduce βA 1-42 aggregation and target multiple disease pathways.
rPeptide’s #BetaAmyloid (1-42) was used to track fibrillation, highlighting plant-based promise in neurodegeneration research.
t.ly/nmxNM
#Neuroscience #Research #rPeptide
rPeptide’s #BetaAmyloid (1-42) was used to track fibrillation, highlighting plant-based promise in neurodegeneration research.
t.ly/nmxNM
#Neuroscience #Research #rPeptide
Researchers found that by tweaking a key clock protein (REV-ERBα) in mice, brain levels of NAD+ went up and harmful tau buildup—a hallmark of #Alzheimers disease — went down.
Adjusting your internal rhythm may one day help protect your brain.
t.ly/xYCMQ
#Tau #Neuroscience #rPeptide
Adjusting your internal rhythm may one day help protect your brain.
t.ly/xYCMQ
#Tau #Neuroscience #rPeptide
Resetting the body’s rhythm could protect the brain from Alzheimer’s
Researchers discovered that altering the body’s natural rhythm can help protect the brain from Alzheimer’s damage. By turning off a circadian protein in mice, they raised NAD+ levels and reduced harmf...
t.ly
November 3, 2025 at 3:07 PM
Researchers found that by tweaking a key clock protein (REV-ERBα) in mice, brain levels of NAD+ went up and harmful tau buildup—a hallmark of #Alzheimers disease — went down.
Adjusting your internal rhythm may one day help protect your brain.
t.ly/xYCMQ
#Tau #Neuroscience #rPeptide
Adjusting your internal rhythm may one day help protect your brain.
t.ly/xYCMQ
#Tau #Neuroscience #rPeptide
October 31, 2025 at 4:15 PM
This highlights the development of a promising antibody therapy, #Amlenetug, designed to target toxic forms of Alpha-Synuclein
Our ASyn and ASyn 1-60 were used to characterize different conformations of the protein and select an antibody with the right binding properties
t.ly/FbB2w
#Research
Our ASyn and ASyn 1-60 were used to characterize different conformations of the protein and select an antibody with the right binding properties
t.ly/FbB2w
#Research
Rational selection of the monoclonal α-synuclein antibody amlenetug (Lu AF82422) for the treatment of α-synucleinopathies - npj Parkinson's Disease
npj Parkinson's Disease - Rational selection of the monoclonal α-synuclein antibody amlenetug (Lu AF82422) for the treatment of α-synucleinopathies
t.ly
October 29, 2025 at 12:32 PM
This highlights the development of a promising antibody therapy, #Amlenetug, designed to target toxic forms of Alpha-Synuclein
Our ASyn and ASyn 1-60 were used to characterize different conformations of the protein and select an antibody with the right binding properties
t.ly/FbB2w
#Research
Our ASyn and ASyn 1-60 were used to characterize different conformations of the protein and select an antibody with the right binding properties
t.ly/FbB2w
#Research
October 27, 2025 at 2:52 PM
Our October Raffle Riddle winner is Aline! 🎉
Please check your email to claim your prize.
Thank you to everyone who participated!
#WinnerAnnouncement #rPeptide #Raffle #Prize
Please check your email to claim your prize.
Thank you to everyone who participated!
#WinnerAnnouncement #rPeptide #Raffle #Prize
October 24, 2025 at 1:19 PM
Our October Raffle Riddle winner is Aline! 🎉
Please check your email to claim your prize.
Thank you to everyone who participated!
#WinnerAnnouncement #rPeptide #Raffle #Prize
Please check your email to claim your prize.
Thank you to everyone who participated!
#WinnerAnnouncement #rPeptide #Raffle #Prize
October 22, 2025 at 3:40 PM
Researchers found that Xanthohumol, a natural compound from hops, can destabilize harmful Amyloid-β oligomers and redirect them into larger, less toxic aggregates.
These findings shed light on how small molecules might shift the course of #Alzheimers by affecting protein aggregation.
t.ly/MYai5
These findings shed light on how small molecules might shift the course of #Alzheimers by affecting protein aggregation.
t.ly/MYai5
Xanthohumol destabilizes the structure of amyloid-β (Aβ) oligomers and promotes the formation of high-molecular-weight amorphous aggregates
This study provides a comprehensive structural analysis of prenylflavonoids (PFs) interaction with Aβ1–42 oligomers, revealing their potential to modu…
t.ly
October 20, 2025 at 2:28 PM
Researchers found that Xanthohumol, a natural compound from hops, can destabilize harmful Amyloid-β oligomers and redirect them into larger, less toxic aggregates.
These findings shed light on how small molecules might shift the course of #Alzheimers by affecting protein aggregation.
t.ly/MYai5
These findings shed light on how small molecules might shift the course of #Alzheimers by affecting protein aggregation.
t.ly/MYai5
Music you can feel — literally! ✨
Researchers found that when we hear and feel music, our emotional response is amplified, sparking more joy and calm!
t.ly/dYYra
#Neuroscience #MusicTherapy #BrainHealth #rPeptide
Researchers found that when we hear and feel music, our emotional response is amplified, sparking more joy and calm!
t.ly/dYYra
#Neuroscience #MusicTherapy #BrainHealth #rPeptide
Feeling the Music: Touch Amplifies Emotional Power of Sound - Neuroscience News
A new study shows that combining touch with hearing profoundly intensifies emotional responses to music.
t.ly
October 17, 2025 at 1:53 PM
Music you can feel — literally! ✨
Researchers found that when we hear and feel music, our emotional response is amplified, sparking more joy and calm!
t.ly/dYYra
#Neuroscience #MusicTherapy #BrainHealth #rPeptide
Researchers found that when we hear and feel music, our emotional response is amplified, sparking more joy and calm!
t.ly/dYYra
#Neuroscience #MusicTherapy #BrainHealth #rPeptide
Can you crack this one? The answer’s right in front of you… but unseen. 👀
#RaffleRiddle #ScienceFun #BrainTeaser #rPeptide
#RaffleRiddle #ScienceFun #BrainTeaser #rPeptide
October 15, 2025 at 12:39 PM
Can you crack this one? The answer’s right in front of you… but unseen. 👀
#RaffleRiddle #ScienceFun #BrainTeaser #rPeptide
#RaffleRiddle #ScienceFun #BrainTeaser #rPeptide
A more standardized approach to detecting synucleinopathies like #Parkinsons Disease & #dementia with #LewyBodies.
A Universal Control Fluid was developed to improve consistency in ASyn RT-QuIC assays to detect misfolded proteins.
t.ly/Yq8oW
#Research #Development
A Universal Control Fluid was developed to improve consistency in ASyn RT-QuIC assays to detect misfolded proteins.
t.ly/Yq8oW
#Research #Development
Seeding amplification assay with Universal Control Fluid: Standardized detection of α-synucleinopathies
Seeding amplification assays, specifically the Real-Time Quaking-Induced Conversion method (RT-QuIC), have shown great diagnostic potential for α-synucleinopathies. Numerous research groups have demon...
t.ly
October 13, 2025 at 4:46 PM
A more standardized approach to detecting synucleinopathies like #Parkinsons Disease & #dementia with #LewyBodies.
A Universal Control Fluid was developed to improve consistency in ASyn RT-QuIC assays to detect misfolded proteins.
t.ly/Yq8oW
#Research #Development
A Universal Control Fluid was developed to improve consistency in ASyn RT-QuIC assays to detect misfolded proteins.
t.ly/Yq8oW
#Research #Development
Making neural connections one class at a time! 🤓🧠
#ScienceHumor #FridayFun #StayingConnected #rPeptide
#ScienceHumor #FridayFun #StayingConnected #rPeptide
October 10, 2025 at 12:54 PM
Making neural connections one class at a time! 🤓🧠
#ScienceHumor #FridayFun #StayingConnected #rPeptide
#ScienceHumor #FridayFun #StayingConnected #rPeptide
This study explores how the ApoE3ch variant may protect against Alzheimer’s by altering Tau protein behavior.
It shows that ApoE3ch reduces Tau spread by disrupting its interaction with cellular receptors, potentially offering a natural protective mechanism against disease progression.
t.ly/Il1PS
It shows that ApoE3ch reduces Tau spread by disrupting its interaction with cellular receptors, potentially offering a natural protective mechanism against disease progression.
t.ly/Il1PS
ApoE3 Christchurch and tau interaction as a protective mechanism against Alzheimer's disease
INTRODUCTION We described a protected case with familial Alzheimer's disease, homozygous for apolipoprotein E3 (APOE3) Christchurch variant (ApoE3Ch), exhibiting low tau protein levels despite genet...
t.ly
October 8, 2025 at 5:21 PM
This study explores how the ApoE3ch variant may protect against Alzheimer’s by altering Tau protein behavior.
It shows that ApoE3ch reduces Tau spread by disrupting its interaction with cellular receptors, potentially offering a natural protective mechanism against disease progression.
t.ly/Il1PS
It shows that ApoE3ch reduces Tau spread by disrupting its interaction with cellular receptors, potentially offering a natural protective mechanism against disease progression.
t.ly/Il1PS
Every big discovery starts with a single spark of curiosity. Let today be the day you chase a thought, test an idea, or take one bold step forward—you never know where it might lead! ✨
#ScienceInspires #CuriosityDriven #MotivationMonday #rPeptide
#ScienceInspires #CuriosityDriven #MotivationMonday #rPeptide
October 6, 2025 at 1:32 PM
Every big discovery starts with a single spark of curiosity. Let today be the day you chase a thought, test an idea, or take one bold step forward—you never know where it might lead! ✨
#ScienceInspires #CuriosityDriven #MotivationMonday #rPeptide
#ScienceInspires #CuriosityDriven #MotivationMonday #rPeptide
It’s not just genetics — lifestyle habits may help slow down cognitive aging.
Exercise, diet, connection — small changes, big impact!
t.ly/m0Cpa
#BrainHealth #DementiaPrevention #Neuroscience #rPeptide
Exercise, diet, connection — small changes, big impact!
t.ly/m0Cpa
#BrainHealth #DementiaPrevention #Neuroscience #rPeptide
Scientists reveal the everyday habits that may shield you from dementia
New studies reveal that lifestyle changes—such as exercise, healthy eating, and social engagement—can help slow or prevent cognitive decline. Experts say this low-cost, powerful approach could transfo...
t.ly
October 3, 2025 at 3:15 PM
It’s not just genetics — lifestyle habits may help slow down cognitive aging.
Exercise, diet, connection — small changes, big impact!
t.ly/m0Cpa
#BrainHealth #DementiaPrevention #Neuroscience #rPeptide
Exercise, diet, connection — small changes, big impact!
t.ly/m0Cpa
#BrainHealth #DementiaPrevention #Neuroscience #rPeptide
This study shows that methylation plays a key role in regulating how microglia clear Beta-Amyloid offering new insight into immune dysfunction in AD. rPeptide’s Aβ peptides continue to advance our understanding of Amyloid-related mechanisms in #Alzheimers & #Parkinsons Disease
t.ly/6eMuy
#Research
t.ly/6eMuy
#Research
t.ly
October 1, 2025 at 4:19 PM
This study shows that methylation plays a key role in regulating how microglia clear Beta-Amyloid offering new insight into immune dysfunction in AD. rPeptide’s Aβ peptides continue to advance our understanding of Amyloid-related mechanisms in #Alzheimers & #Parkinsons Disease
t.ly/6eMuy
#Research
t.ly/6eMuy
#Research
Who knew one of the ocean’s smartest creatures had three hearts? 🐙 Science never ceases to surprise us! ♥️
#ScienceFacts #ScienceFun #rPeptide
#ScienceFacts #ScienceFun #rPeptide
September 29, 2025 at 1:54 PM
Who knew one of the ocean’s smartest creatures had three hearts? 🐙 Science never ceases to surprise us! ♥️
#ScienceFacts #ScienceFun #rPeptide
#ScienceFacts #ScienceFun #rPeptide
Our September Raffle Riddle winner is Hirra! 🎉
Please check your email to claim your prize.
Thank you to everyone who participated!
#WinnerAnnouncement #rPeptide #Raffle #Prize #StayTuned #October
Please check your email to claim your prize.
Thank you to everyone who participated!
#WinnerAnnouncement #rPeptide #Raffle #Prize #StayTuned #October
September 26, 2025 at 3:32 PM
Our September Raffle Riddle winner is Hirra! 🎉
Please check your email to claim your prize.
Thank you to everyone who participated!
#WinnerAnnouncement #rPeptide #Raffle #Prize #StayTuned #October
Please check your email to claim your prize.
Thank you to everyone who participated!
#WinnerAnnouncement #rPeptide #Raffle #Prize #StayTuned #October
Thought-processing, cell-firing, and mighty without moving — this month’s Raffle Riddle answer is the brain! 🧠
#RaffleRiddle #ScienceFun #rPeptide
#RaffleRiddle #ScienceFun #rPeptide
September 24, 2025 at 4:06 PM
Thought-processing, cell-firing, and mighty without moving — this month’s Raffle Riddle answer is the brain! 🧠
#RaffleRiddle #ScienceFun #rPeptide
#RaffleRiddle #ScienceFun #rPeptide
A recent study sheds light on how early changes in Alpha-Synuclein may drive Parkinson's Disease. Researchers found that the phosphorylated form of Alpha-Synuclein (pSer129) builds up specifically at dopamine-releasing synapses in the brain during the earliest stages of disease.
t.ly/0G59b
t.ly/0G59b
Synaptic enrichment of pSer129 alpha-synuclein correlates with dopaminergic denervation in early-stage Parkinson’s disease - Nature Communications
α-Synuclein accumulation in putaminal synapses is hypothesised to drive Parkinson’s disease progression. This study demonstrates synaptic pSer129 α-synuclein enrichment in early-stage Parkinson’s dise...
t.ly
September 22, 2025 at 12:44 PM
A recent study sheds light on how early changes in Alpha-Synuclein may drive Parkinson's Disease. Researchers found that the phosphorylated form of Alpha-Synuclein (pSer129) builds up specifically at dopamine-releasing synapses in the brain during the earliest stages of disease.
t.ly/0G59b
t.ly/0G59b
It’s that time again — Raffle Riddle time!
Think you can solve it?
⚡Comment/message your answer for a chance to win!
#RiddleMeThis #ScienceFun #BrainTeaser #ResearchCommunity #rPeptide
Think you can solve it?
⚡Comment/message your answer for a chance to win!
#RiddleMeThis #ScienceFun #BrainTeaser #ResearchCommunity #rPeptide
September 17, 2025 at 2:38 PM
It’s that time again — Raffle Riddle time!
Think you can solve it?
⚡Comment/message your answer for a chance to win!
#RiddleMeThis #ScienceFun #BrainTeaser #ResearchCommunity #rPeptide
Think you can solve it?
⚡Comment/message your answer for a chance to win!
#RiddleMeThis #ScienceFun #BrainTeaser #ResearchCommunity #rPeptide
A recent study used human Plasminogen provided by #rPeptide to show activity of a plant-made nattokinase, an enzyme that breaks down blood clots.
The mature form of the enzyme worked without damaging plant tissue and could break down fibrin when tested with human plasminogen.
t.ly/yLg-o
The mature form of the enzyme worked without damaging plant tissue and could break down fibrin when tested with human plasminogen.
t.ly/yLg-o
Frontiers | Transient expression of full-length and mature nattokinase in Nicotiana benthamiana reveals early necrosis from full-length form and functional activity of the mature enzyme
Nattokinase is a potent fibrinolytic enzyme widely used in the treatment of cardiovascular diseases for its ability to directly degrade fibrin and plasmin su...
t.ly
September 15, 2025 at 2:43 PM
A recent study used human Plasminogen provided by #rPeptide to show activity of a plant-made nattokinase, an enzyme that breaks down blood clots.
The mature form of the enzyme worked without damaging plant tissue and could break down fibrin when tested with human plasminogen.
t.ly/yLg-o
The mature form of the enzyme worked without damaging plant tissue and could break down fibrin when tested with human plasminogen.
t.ly/yLg-o