Thank you to everyone who supported, discussed, and encouraged this work!

In our study, we show that critical point drying (CPD), a resin-free sample prep method, enhances contrast in X-ray phase-contrast imaging of brain tissue, with largely preserving ultrastructure.

✅ Compatible with femtosecond laser & plasma-FIB milling
✅ Effective for stained and unstained tissue

Our pre-print is out!
Critical point drying of brain tissue for x-ray phase contrast imaging.
@apeart.bsky.social @yuxinzhang.bsky.social @jkbrmn.bsky.social @apacureanu.bsky.social @andreas-t-schaefer.bsky.social
@carlesbosch.bsky.social
@esrf.fr
@crick.ac.uk
bioarXiv: doi.org/10.1101/2025...