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Safer Medicines @safermedicines.org · 2d

The UK government promised to phase out animal testing. A promise isn't enough. We need an ambitious roadmap with firm deadlines, not more delays. Sign the petition demanding a real plan to bring UK science into the 21st century. you.38degrees.org.uk/petitions/a-...

A real roadmap to phase out animal testing

It's time for the UK to catch up and focus on modern, human-relevant science. Add your name to the petition calling on the government to create an ambitious and detailed roadmap to phase out animal te...

you.38degrees.org.uk

Safer Medicines @safermedicines.org · Sep 3

Sign and share this petition to make sure animal testing is REALLY phased out in the UK! #betterscience #humanrelevant you.38degrees.org.uk/petitions/a-...

A real roadmap to phase out animal testing

The government promised to work towards phasing out animal testing. Now they're creating a roadmap to make it happen, but it needs to be an ambitious and detailed plan, with clear milestones to drive ...

you.38degrees.org.uk

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Safer Medicines @safermedicines.org · Jul 24

Defending animal research in the USA - our latest blog

safermedicines.org/blog_post/ho...

How are US organisations that promote animal research responding to recent developments? - Safer Medicines

Recent developments in the US have taken us all by surprise, not only because they were unanticipated, but also due to their breadth and ambition. First the Food and Drug Administration (FDA) declared...

safermedicines.org

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Safer Medicines @safermedicines.org · Jul 18

Will the UK government's forthcoming strategy to reduce the use of animals in science reflect the bold developments in the US?

safermedicines.org/blog_post/fd...

FDA-NIH Workshop: Reducing Animal Testing - Safer Medicines

A cultural shift Much has been written about Nicole Kleinstreuer’s announcement in the joint workshop between the FDA and the National Institutes for Health (NIH), namely that all new NIH funding oppo...

safermedicines.org

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Safer Medicines @safermedicines.org · May 20

Patients would benefit from human-relevant science in place of preclinical animal tests that risk incorrect predictions of safety and efficacy. #betterscience #humanrelevant safermedicines.org/blog_post/on...

On Clinical Trials Day - May 20 2025 - Safer Medicines

May 20th every year marks Clinical Trials Day, to recognise the day in 1747 when James Lind, a ship’s surgeon in the British Royal Navy initiated what is considered to be one of the first ever clinica...

safermedicines.org

Safer Medicines @safermedicines.org · May 2

UK government needs to quickly up its game, or be left in the dirt by the forward-thinking US FDA, NIH and EPA, who now realise that #betterscience is #humanrelevant

safermedicines.org/blog_post/as...

Astonishing April! - Safer Medicines

It all began on 10th April, when the US Food and DrugAdministration (FDA) announced its intention to take ‘a groundbreaking step to advance public health’ by using ‘more effective, human-relevant meth...

safermedicines.org

Safer Medicines @safermedicines.org · Apr 25

Vivodyne human tissues are making human-first drug testing a reality... yielding rich human data without relying on animal vivariums 👏https://www.contractpharma.com/exclusives/advantages-and-impact-of-fdas-plan-to-phase-out-animal-testing-for-mabs-and-other-drugs/

Advantages and Impact of FDA’s Plan to Phase Out Animal Testing for mAbs and Other Drugs

Andrei Georgescu of Vivodyne discusses key advantages of its humanized drug testing platform and the impact of the FDA’s policy shift.

www.contractpharma.com

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Safer Medicines @safermedicines.org · Apr 19

Experimental methods that don’t use animals, like tissue chips and computational models, lead to the development of safer and more effective therapies and pharmaceuticals.

#betterscience #humanrelevant

utahnewsdispatch.com/2025/04/16/k...

Kudos to the FDA and EPA for planning to phase out animal testing • Utah News Dispatch

Commentary: The Food and Drug Administration and the Environmental Protection Agency say they will start backing off of animal testing.

utahnewsdispatch.com

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Reposted by Safer Medicines

Dynamic42 @dynamic42.bsky.social · Feb 18

“This is a lot easier than I thought!” We hear this often after our workshops. And it's true #organonchip doesn't need to be complicated as long as you start with the small questions & increase complexity with time. The video shows our Online Academy, an e-learning platform for learning #ooc tech.

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Reposted by Safer Medicines

Dynamic42 @dynamic42.bsky.social · Feb 19

[𝐍𝐞𝐰 𝐛𝐥𝐨𝐠] Only ~10% of drugs have been tested for safety in pregnant women, risking unexpected side effects. In collaboration with esqLABs, Bayer & Placenta Lab we developed an #organonchip platform to study if small molecules can cross the blood-placenta-barrier. Read it here: shorturl.at/5gfpY

3D Intestine-on-chip model to understand fungal infection

Summary of our recent publication on an intestine-on-chip model for gaining a deeper understanding of the pathogenicity mechanisms of Candida albicans.

shorturl.at

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Reposted by Safer Medicines

Dynamic42 @dynamic42.bsky.social · Mar 13

[𝐍𝐞𝐰 𝐛𝐥𝐨𝐠] The PDAC-on-Chip – A New Dimension in Pancreatic Cancer Research. Read a summary of the most important findings of our recent study with the team of Prof. Dr. Nicole Teusch at the University of Düsseldorf here: zurl.co/7pdot
#drugdevelopment #cancer #spheroids #preclinic

The PDAC-on-Chip - A New Dimension in Pancreatic Cancer Research

A new biochip replicates key aspects of the PDAC microenvironment, providing a powerful tool for drug development and reduction of animal testing.

dynamic42.com

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Reposted by Safer Medicines

Dynamic42 @dynamic42.bsky.social · Apr 14

👏 the good news we all needed! FDA announces to replace animal testing with more effective, human-relevant methods including #organonchip. Below, we've summarized the most important points. Curious about organ models? We help researchers bridge the gap between 2D cell culture and animal models.

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Reposted by Safer Medicines

Dynamic42 @dynamic42.bsky.social · Apr 15

Organ models trump traditional 2D models for studying barrier function. They recreate the complex microenvironments of specific organs and allow for a more consistent and reproducible way of measuring TEER.

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Safer Medicines @safermedicines.org · Apr 16

Dirty tricks campaign by pro-animal research lobby in Germany

www.aerzte-gegen-tierversuche.de/en/news/ques...

Questionable pro-animal testing campaign planned

Science lobby prepares massive PR push against reduction strategy Science lobby prepares massive PR push against reduction strategy In the run-up...

www.aerzte-gegen-tierversuche.de

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Reposted by Safer Medicines

Eurogroup for Animals @eurogroupforanimals.org · Mar 31

👏❤️ The “Patients are human” campaign by @keintierversuch.bsky.social amplifies the voices of those fighting serious illnesses (ex: multiple sclerosis, breast cancer, endometriosis, epilepsy, prostate Cancer, bipolar disorder,...) & opposing animal experiments.

🔗 Learn more:

Patients are human: challenging animal experiments in medical research

A common misconception suggests that patients with severe illnesses support animal experiments in the hope of finding a cure. But the reality is different. Many patients are speaking out against the…

bit.ly

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Safer Medicines @safermedicines.org · Mar 2

Thank you - enjoy!

Safer Medicines @safermedicines.org · Mar 1

Fabulous review of Rat Trap by Carla Owen of
@afruk.bsky.social - thanks Carla 😀👏
Read the e-book or paperback now 🙏

open.substack.com/pub/animalfr...

Rat Trap by Pandora Pound - book review

🐀 The capture of medicine by animal research and how to break free

open.substack.com

Safer Medicines @safermedicines.org · Feb 27

@healthfoundation.bsky.social @cebmoxford.bsky.social @pscommissioner.bsky.social @patientsafetylearning.org @drug-evidence.bsky.social

Safer Medicines @safermedicines.org · Feb 25

A short blog on our new study published in JRSM Open: safermedicines.org/blog_post/ac...

Access to life-saving drugs for seriously ill patients, or easy money for pharmaceutical companies? - Safer Medicines

Can a regulator make it as easy as possible for companies to market their products and at the same time protect the public health?

safermedicines.org

Safer Medicines @safermedicines.org · Feb 26

Worrying trends uncovered in an analysis of 10 years of the UK's Early Access to Medicines Scheme: journals.sagepub.com/doi/10.1177/... - see also our short blog: safermedicines.org/blog_post/ac...

Healthwatch England @healthwatchengland.bsky.social · Feb 24

Most of us spend a lot of time each day scrolling on our phone! You could take just 3 minutes to tell us about your health or social care experiences and help improve these services for everyone. #ShareForBetterCare bit.ly/BetterCareFe...

On average people spend nearly 2 hours a day scrolling on their phone. Photo of a woman scrolling on a digital screen.

Safer Medicines @safermedicines.org · Feb 25

A short blog on our new study published in JRSM Open: safermedicines.org/blog_post/ac...

Access to life-saving drugs for seriously ill patients, or easy money for pharmaceutical companies? - Safer Medicines

Can a regulator make it as easy as possible for companies to market their products and at the same time protect the public health?

safermedicines.org

Reposted by Safer Medicines

Emily R. Trunnell, Ph.D. @ertrunnell.bsky.social · Feb 24

In this blog post, @dynamic42.bsky.social showcases their #OrganOnChip models for #InfectiousDisease research & discusses how these models are instrumental for unraveling infection mechanisms & developing new therapies. dynamic42.com/exploring-in... 🧪

Exploring infectious disease dynamics through organ-on-chip technology

This blog explores established infection models using organ-on-chip technology and their implications for scientific research.

dynamic42.com

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Safer Medicines @safermedicines.org · Feb 24

Are desperate patients, likely unaware of the uncertainty surrounding the risk-benefit profile of fast-tracked drugs, simply a money-making machine for pharmaceutical companies?

journals.sagepub.com/doi/10.1177/...

The UK's Early Access to Medicines Scheme 10 years on: an evaluation using publicly available data - Pandora Pound, Rebecca Ram, Kathy Archibald, 2025

Objectives To investigate the drugs and indications that have passed through the UK's Early Access to Medicines Scheme (EAMS) to date, the type of evidence the ...

journals.sagepub.com

Safer Medicines @safermedicines.org · Feb 19

Animal tests are notoriously bad at identifying liver-toxic drugs. Now is the time to implement predictive complex in vitro models of human livers into routine drug testing #betterscience #humanrelevant

www.frontiersin.org/journals/dru...

Frontiers | Perspective: How complex in vitro models are addressing the challenges of predicting drug-induced liver injury

www.frontiersin.org

Safer Medicines @safermedicines.org · Feb 17

“I’m not a mouse, I’m not even a monkey,” she says. “When we are doing drug testing in animals, and then we take it into a clinical trial in humans we see a lot of drugs fail.” #betterscience #humanrelevant

www.theguardian.com/environment/...

The world is shifting away from using animals in research. Will Australia get left behind?

Australia’s lack of transparency and funding leave it on the outer as researchers worldwide explore alternatives for training, study and testing

www.theguardian.com

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Safer Medicines @safermedicines.org · Feb 14

“We’re not going to be able to replace animals in biomedical research with the meager investments that federal agencies are now making.”

#betterscience #humanrelevant

thehighwire.com/news/house-o...

House Oversight Committee Exposes “Barbaric” Taxpayer-Funded Animal Experiments - The HighWire

Lawmakers detail shocking taxpayer-funded animal experiments, including drugged puppies, transgender lab rats, and gain-of-function research.

thehighwire.com