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Reposted by Simon Eickhoff

Neurobiology of Aging @neurobiology-aging.bsky.social · 4d

✨ SHINY NEW PAPER ✨

Sleep-disordered breathing is associated with higher Aβ burden, lower rFDG, and worse cognition in Alzheimer's Disease.

@sbe.bsky.social

www.sciencedirect.com/science/article/pii/S0197458025001034

How is self-reported sleep-disordered breathing linked with biomarkers of Alzheimer’s disease?

Sleep-disordered breathing (SDB) is prevalent in Alzheimer’s disease (AD). Here, we assessed how self-reported SDB is linked with AD biomarkers, inclu…

www.sciencedirect.com

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Reposted by Simon Eickhoff

Pascal Grumbach @pascal-grumbach.bsky.social · 24d

Excited to see this work published in @natcomms.nature.com! 🧠📊 In-vivo evidence of E/I alterations underlying functional changes in individuals with autism in the large ABIDE1 dataset AND replication in the independent ABIDE2 dataset.

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Reposted by Simon Eickhoff

Ted Satterthwaite @ted-satterthwaite.bsky.social · Sep 7

New preprint from stellar IRTG PhD student Amelie Rauland + team on white matter bundle reconstruction! Shows that WM bundles can be reliably extracted from simple 32-direction dMRI & features predict cognition - huge potential for legacy and clinical data. Thread 👇

www.biorxiv.org/cgi/content/...

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Reposted by Simon Eickhoff

Meike Hettwer @meikehettwer.bsky.social · Aug 25

The end of a PhD journey 🎓 What a ride - full of lovely people, exciting science, coding tunnels, coffee-brainstorms & amazing conferences! Whole-hearted thank you to all who shared the journey & celebrated with me - especially @sofievalk.bsky.social, @sbe.bsky.social [email protected] 💐🥳❤️

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Reposted by Simon Eickhoff

Thomas Yeo @bttyeo.bsky.social · Jul 17

1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social

AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...

doi.org/10.1038/s415...

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Reposted by Simon Eickhoff

Ted Satterthwaite @ted-satterthwaite.bsky.social · Jun 25

Amelie Rauland (all star via IRTG student w/ @sbe.bsky.social ) will be presenting "Benchmarking Reconstruction Methods for Bundle Segmentation in Single-Shell dMRI" on Friday and Saturday, Poster #1283

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Reposted by Simon Eickhoff

ABCD-J @abcd-j.bsky.social · Jun 6

#ABCD-J #Studienhighlights: Eine kürzlich erschienene Studie zeigt mittels #JTrack Social Unterschiede in Kommunikationsmustern zwischen neurotypischen Erwachsenen und Erwachsenen mit #Autismus-Spektrum-Störung auf. Neugierig geworden? Das ganze Highlight gibt es hier: www.abcd-j.de/de/showcases...

Mehrere Liniendiagramme, die die durchschnittliche tägliche Nutzungsdauer von Smartphones in verschiedenen Kommunikationskategorien zeigen. In Türkis sind jeweils die Daten der Kontrollgruppe mit typischer neurologischer Entwicklung (TD) abgebildet, und in rosa die Daten der Erwachsenen mit Autismus-Spektrum-Störung (ASD). In der Gesamtkommunikation zeigt sich kein Unterschied zwischen den Gruppen (unterste Grafik). Die TD Gruppe nutzt jedoch mehr verbale Kommunikation als die ASD Gruppe (oberste Grafik), während die ASD Gruppe mehr schriftliche Kommunikation nutzt (zweite Grafik).

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Reposted by Simon Eickhoff

Amin Saberi @amnsbr.bsky.social · Jun 5

🧠⚖️📉 How does the cortical excitation-inhibition ratio mature during adolescence?
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️

Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling

Individualized simulations reveal a decrease in excitation-inhibition ratio in association areas throughout adolescence.

www.science.org

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Reposted by Simon Eickhoff

Boris Bernhardt @borismontreal.bsky.social · Jun 5

⭐ new paper

Maturation of cortical excitation-inhibition (EI) in adolescence

now in Science Advances 💥

A true tour de force of multimodal MRI, connectomics & GPU-powered 🤖!! biophysical modelling

by hiball superheroes 🦸‍♂️🦸‍♀️🦸‍♂️
@amnsbr.bsky.social @sofievalk.bsky.social @sbe.bsky.social

Amin Saberi @amnsbr.bsky.social · Jun 5

🧠⚖️📉 How does the cortical excitation-inhibition ratio mature during adolescence?
We asked this in our new paper just out in #ScienceAdvances ✨
“Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling”
📄 www.science.org/doi/full/10....
🧵⤵️

Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling

Individualized simulations reveal a decrease in excitation-inhibition ratio in association areas throughout adolescence.

www.science.org

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Simon Eickhoff @sbe.bsky.social · May 1

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Simon Eickhoff @sbe.bsky.social · Apr 24

Our #metaanalysis (n = 231) in JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus

Short-term sleep deprivation shows a distinct picture, affecting the thalamus

jamanetwork.com/journals/jam...

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Reposted by Simon Eickhoff

Thomas Yeo @bttyeo.bsky.social · Mar 26

It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠

A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications

Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.

www.nature.com

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Reposted by Simon Eickhoff

NeuroecologyLab @neuroecologylab.bsky.social · Mar 18

Always thought we should use connectivity blueprints to investigate differences between human, chimpanzee, and macaque brains? www.jneurosci.org/content/earl... For Katherine Bryant’s latest masterpiece.

Connectivity profile and function of uniquely human cortical areas

Determining the brain specializations unique to humans requires directly comparative anatomical information from other primates, especially our closest relatives. Human ( Homo sapiens ) (m/f), chimpan...

www.jneurosci.org

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Simon Eickhoff @sbe.bsky.social · Mar 14

Analysis Methods: 11:00 – 11:30
Harmonize: Leakage in data harmonization
JuSpace: cross-modal brain map correlation

Applied Concepts: 11:30 – 12:00
Causal modeling for Confounds in ML
Subtypes of major depression

Simon Eickhoff @sbe.bsky.social · Mar 14

NOW, Join if you're interessted
Topic: DGKN Hackroom 2025 — Tool Talks
Time: Mar 14, 2025 10:30 - 12h
fz-juelich-de.zoom.us/j/6792251876...

Data Management: 10:30 – 11:00
Datalad: GPDR conform collaboration
Jtrack: remote wearable assessment

Join our Cloud HD Video Meeting

Zoom is the leader in modern enterprise video communications, with an easy, reliable cloud platform for video and audio conferencing, chat, and webinars across mobile, desktop, and room systems. Zoom ...

fz-juelich-de.zoom.us

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Reposted by Simon Eickhoff

Juergen Dukart @juergendukart.bsky.social · Mar 12

Now out in NPJ Digital Medicine our manuscript on real-world evidence for altered communication preferences in autism: nature.com/articles/s41...
@sbe.bsky.social
@leoschilbach.bsky.social

Real world evidence for altered communication patterns in individuals with autism spectrum disorder - npj Digital Medicine

npj Digital Medicine - Real world evidence for altered communication patterns in individuals with autism spectrum disorder

nature.com

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Reposted by Simon Eickhoff

OHBM Communications Committee (ComCom) @ohbm-com.com · Mar 6

A new #Neurosalience episode is out! 🧠

From Big Data to Biomarkers
with Peter Bandettini @fmri-today.bsky.social and Simon Eickhoff @sbe.bsky.social

youtu.be/z91SiENsgF8

Neurosalience #S5E10 with Simon Eickhoff - From Big Data to Biomarkers

YouTube video by Organization for Human Brain Mapping

youtu.be

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Reposted by Simon Eickhoff

ABCD-J @abcd-j.bsky.social · Mar 4

Dazu integrieren wir – das Institut für Neurowissenschaften und Medizin: Gehirn und Verhalten (INM-7) @fz-juelich.de, und unsere klinischen Partner an den Unikliniken Aachen, Bonn, Köln, und Düsseldorf – verschiedene technische Lösungen zu einer digitalen Plattform und vernetzen uns.

ABCD-J @abcd-j.bsky.social · Mar 4

Hallo Bluesky! Zeit für unsere #Vorstellung. Hier postet das #ABCD-J Projekt. Wir sind eine vom Land NRW geförderte Initiative für die Verbesserung von klinischer Forschung mittels #Biomarkern und #mobileHealth.

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Reposted by Simon Eickhoff

Thomas Yeo @bttyeo.bsky.social · Jan 24

Thanks to everyone's feedback, we have updated our calculator to optimize sample size N & scan time T for fMRI studies: leonoqr.github.io/ORSP_Calcula...

The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵

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Simon Eickhoff @sbe.bsky.social · Dec 16

Fully agreed. This adds another layer of complexity

We likely need to differentiate three aspects here
- "True" changes of the trait
- State-changes due to, e.g., sleep
- Measurement error

All three can and will superimpose

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Simon Eickhoff @sbe.bsky.social · Dec 14

In my view, the take-home message is slightly different from the BWAS paper. The latter argued you need large N.

This paper shows that if your target is unreliable, even very large numbers can’t save you

Also, association vs prediction

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Simon Eickhoff @sbe.bsky.social · Dec 13

The limiting factor for MRI based prediction of behavioral traits may be neither the imaging nor the pipeline or learning algorith but rather the reliability of the target phenotypes

Thought provoking work my Martin Gell et al:

www.nature.com/articles/s41...

How measurement noise limits the accuracy of brain-behaviour predictions - Nature Communications

Our ability to identify associations between behaviour and brain imaging is important for uncovering markers of cognition and disease. Here, the authors illustrate the importance of the reliability of...

www.nature.com

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Simon Eickhoff @sbe.bsky.social · Dec 3

This is what happens if preprints are treated as „scientific literature“

Don’t get me wrong, I am all for preprinting. But unfortunately, it is often ignored that anybody can preprint anything

Mark Pallen @mjpallen.bsky.social · Dec 3

Letter sent in to the Editor of the Guardian on brain microbiome nonsense.

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Reposted by Simon Eickhoff

INCF @incforg.bsky.social · Nov 19

We created a #neuroinformagical (obvs) starter pack! Let us know who else to add!
#openscience #datasharing #neuroskyence 🧪

go.bsky.app/LRqnaMP

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