Siyuan Ding
@sding88.bsky.social
26 followers 36 following 6 posts
Assistant Professor of Molecular Microbiology at WashU
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sding88.bsky.social
My first graduate student so it is truly a milestone for our lab! @washumicrobiology.bsky.social
sding88.bsky.social
Congratulations to Juhee on a stellar thesis defense! Clear, thoughtful, and thorough. Your work on rotavirus and SARS-CoV-2 reflects incredible perseverance. It's been a privilege watching you grow into an independent scientist. Wishing you all the best in your next chapter!🎓👏
sding88.bsky.social
Great collaborations with lots of people including folks from the Sibley, Liu, Shen, and Dermody labs. @washumicrobiology.bsky.social @natcommag.bsky.social
sding88.bsky.social
Its function is highly conserved in multiple cell types including primary human intestinal epithelial cells and hepatocytes and many vertebrate species.

I presented part of this data at ASV2023 almost two years ago! Very happy to see it comes to fruition! Truly a heroic effort by Gaopeng.
sding88.bsky.social
First post on Bluesky! Excited to share the first paper from our lab in 2025! cell.com/cell-host-mi.... Our study demonstrates that UV-inactivated replication-defective rotaviruses can cause diarrhea in neonatal mice, suggesting the host response also contributes to diarrhea to flush out the virus.
Innate immune sensing of rotavirus by intestinal epithelial cells leads to diarrhea
Hou et al. demonstrate in an infant mouse model that innate immune sensing of enteric viruses induces IFN-λ signaling, which downregulates an apical chloride exchanger that leads to increased intestin...
cell.com