Kahlil Lawless
@synthesisconduit.bsky.social
Genomics industry professional, molecular biologist, Dad, adventurer, amateur author/musician/athlete, employed by Illumina but opinions are my own
Reposted by Kahlil Lawless
Registration for the Physalia online course "eDNA Metabarcoding" is now open (Feb 23-27, 2026). Learn biodiversity assessment techniques. More info: https://www.physalia-courses.org/courses-workshops/course4/ #course
eDNA metabarcoding
23-27 February 2026 To foster international participation, this course will be held online
www.physalia-courses.org
November 13, 2025 at 2:54 PM
Registration for the Physalia online course "eDNA Metabarcoding" is now open (Feb 23-27, 2026). Learn biodiversity assessment techniques. More info: https://www.physalia-courses.org/courses-workshops/course4/ #course
Reposted by Kahlil Lawless
I’ve been in Toronto at the #astmh meeting these past few days and last night some very good news was presented here: A new malaria drug has proven efficacious in a large trial and could soon be approved.🧪
My story in @science.org (and 🧵on why it's important to come):
www.science.org/content/arti...
My story in @science.org (and 🧵on why it's important to come):
www.science.org/content/arti...
‘A sigh of relief’: New malaria drug succeeds in large clinical trial
As existing drugs falter because of resistance, the world gets a backup—but hard choices loom on how to use it
www.science.org
November 13, 2025 at 1:27 PM
I’ve been in Toronto at the #astmh meeting these past few days and last night some very good news was presented here: A new malaria drug has proven efficacious in a large trial and could soon be approved.🧪
My story in @science.org (and 🧵on why it's important to come):
www.science.org/content/arti...
My story in @science.org (and 🧵on why it's important to come):
www.science.org/content/arti...
Reposted by Kahlil Lawless
‼️ There are an unprecedented number of Institute Director vacancies at the NIH and many of the application windows close this week or next, including ones that are essential to genomics research in the US including NHGRI, NLM/NCBI, and NIGMS. Please spread the word: hr.nih.gov/careers/open...
hr.nih.gov
November 10, 2025 at 4:08 PM
‼️ There are an unprecedented number of Institute Director vacancies at the NIH and many of the application windows close this week or next, including ones that are essential to genomics research in the US including NHGRI, NLM/NCBI, and NIGMS. Please spread the word: hr.nih.gov/careers/open...
Reposted by Kahlil Lawless
Explore the origins, patterns and consequences of mutations across biological systems! #MITS26
🗓️ Conference dates: 13-15 April 2026
Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬
Check out our exciting speakers ➡️ bit.ly/4hmbnyr
#Genomics
🗓️ Conference dates: 13-15 April 2026
Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬
Check out our exciting speakers ➡️ bit.ly/4hmbnyr
#Genomics
October 27, 2025 at 8:00 AM
Explore the origins, patterns and consequences of mutations across biological systems! #MITS26
🗓️ Conference dates: 13-15 April 2026
Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬
Check out our exciting speakers ➡️ bit.ly/4hmbnyr
#Genomics
🗓️ Conference dates: 13-15 April 2026
Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬
Check out our exciting speakers ➡️ bit.ly/4hmbnyr
#Genomics
Reposted by Kahlil Lawless
📢 We’re hiring!
The DSMZ is looking for a Scientific Lead for the SILVA Database — a unique opportunity to shape one of the world’s most important scientific resources for microbial taxonomy and ecology.
Apply now and help us shape the future of microbial research.
👉 www.dsmz.de/dsmz/career/...
The DSMZ is looking for a Scientific Lead for the SILVA Database — a unique opportunity to shape one of the world’s most important scientific resources for microbial taxonomy and ecology.
Apply now and help us shape the future of microbial research.
👉 www.dsmz.de/dsmz/career/...
November 3, 2025 at 9:52 AM
📢 We’re hiring!
The DSMZ is looking for a Scientific Lead for the SILVA Database — a unique opportunity to shape one of the world’s most important scientific resources for microbial taxonomy and ecology.
Apply now and help us shape the future of microbial research.
👉 www.dsmz.de/dsmz/career/...
The DSMZ is looking for a Scientific Lead for the SILVA Database — a unique opportunity to shape one of the world’s most important scientific resources for microbial taxonomy and ecology.
Apply now and help us shape the future of microbial research.
👉 www.dsmz.de/dsmz/career/...
Proteomic Biomarker Discovery and Analysis in Complex Diseases - upcoming webinar
event.on24.com/wcc/r/510138...
event.on24.com/wcc/r/510138...
Proteomic Biomarker Discovery and Analysis in Complex Diseases
Wednesday, November 19, 2025 at 2:00 PM Eastern Standard Time.
event.on24.com
October 29, 2025 at 1:18 PM
Proteomic Biomarker Discovery and Analysis in Complex Diseases - upcoming webinar
event.on24.com/wcc/r/510138...
event.on24.com/wcc/r/510138...
The Road to Diagnosis: Why Genetic Testing Matters in Rare Diseases
youtu.be/ofqVTzdeshs?...
youtu.be/ofqVTzdeshs?...
The Road to Diagnosis: Why Genetic Testing Matters in Rare Diseases
YouTube video by Illumina
youtu.be
October 27, 2025 at 4:09 PM
The Road to Diagnosis: Why Genetic Testing Matters in Rare Diseases
youtu.be/ofqVTzdeshs?...
youtu.be/ofqVTzdeshs?...
Reposted by Kahlil Lawless
My institution---the Sloan Kettering Institute, the basic science arm of the Memorial Sloan Kettering Cancer Center---is hiring new faculty this cycle! Applications close Nov 15.
www.mskcc.org/research/ski...
www.mskcc.org/research/ski...
Faculty Positions
The Sloan Kettering Institute is seeking innovative scientists to join our faculty.
www.mskcc.org
October 27, 2025 at 2:45 PM
My institution---the Sloan Kettering Institute, the basic science arm of the Memorial Sloan Kettering Cancer Center---is hiring new faculty this cycle! Applications close Nov 15.
www.mskcc.org/research/ski...
www.mskcc.org/research/ski...
Reposted by Kahlil Lawless
🎉 This month we celebrate an important milestone for @biogeneurope.bsky.social: more than 100 genomes have been sequenced as part of the project!!
👏 Congratulations & thanks to all project partners for their dedicated work!
www.erga-biodiversity.eu/post/celebra... @ebpgenome.bsky.social
👏 Congratulations & thanks to all project partners for their dedicated work!
www.erga-biodiversity.eu/post/celebra... @ebpgenome.bsky.social
Celebrating 100+ BGE genomes!
In October 2025, Biodiversity Genomics Europe (BGE) reached a milestone: over one hundred genomes have been sequenced and publicly released as part of the project. More than simply collecting samples ...
www.erga-biodiversity.eu
October 27, 2025 at 2:56 PM
🎉 This month we celebrate an important milestone for @biogeneurope.bsky.social: more than 100 genomes have been sequenced as part of the project!!
👏 Congratulations & thanks to all project partners for their dedicated work!
www.erga-biodiversity.eu/post/celebra... @ebpgenome.bsky.social
👏 Congratulations & thanks to all project partners for their dedicated work!
www.erga-biodiversity.eu/post/celebra... @ebpgenome.bsky.social
Reposted by Kahlil Lawless
For over 20 years, the mouse model organism has helped scientists uncover the biology behind human health and disease.
But the mouse reference genomes still have missing pieces.
The first collection of telomere-to-telomere mouse genomes are now available for two key mouse strains.
🧬💻
But the mouse reference genomes still have missing pieces.
The first collection of telomere-to-telomere mouse genomes are now available for two key mouse strains.
🧬💻
October 27, 2025 at 11:51 AM
For over 20 years, the mouse model organism has helped scientists uncover the biology behind human health and disease.
But the mouse reference genomes still have missing pieces.
The first collection of telomere-to-telomere mouse genomes are now available for two key mouse strains.
🧬💻
But the mouse reference genomes still have missing pieces.
The first collection of telomere-to-telomere mouse genomes are now available for two key mouse strains.
🧬💻
70 companies have been started by Illumina veterans, and those companies have raised over $5 billion in capital - per Jay Flatley
www.genomeweb.com/sequencing/q...
www.genomeweb.com/sequencing/q...
Q&A: Jay Flatley on His Biggest Business Decisions and the Future of Sequencing
The former Illumina executive shared highlights from his tenure at the firm as well as his thoughts on the seeds he and other company alumni have planted in the field.
www.genomeweb.com
October 23, 2025 at 9:42 PM
70 companies have been started by Illumina veterans, and those companies have raised over $5 billion in capital - per Jay Flatley
www.genomeweb.com/sequencing/q...
www.genomeweb.com/sequencing/q...
Reposted by Kahlil Lawless
VERY proud to release the first version of the OceanOmics per-site #eDNA reports: every site we sampled over the past 4 years, summarised and visualised. We have >5,500 samples over 950 sites, so eventually we will have 950 reports.
Features:
(Thread: 1/6)
Features:
(Thread: 1/6)
October 23, 2025 at 11:06 AM
VERY proud to release the first version of the OceanOmics per-site #eDNA reports: every site we sampled over the past 4 years, summarised and visualised. We have >5,500 samples over 950 sites, so eventually we will have 950 reports.
Features:
(Thread: 1/6)
Features:
(Thread: 1/6)
Reposted by Kahlil Lawless
Monty Python understood p-hacking
October 23, 2025 at 8:43 AM
Monty Python understood p-hacking
Constellation illuminates rare disease genetics
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Constellation illuminates rare disease genetics
Despite significant advances in genomic sequencing, the resolution of many rare disease cases is still hindered by variant detection limitations. Short reads struggle in homologous regions, and long r...
www.medrxiv.org
October 20, 2025 at 5:22 PM
Constellation illuminates rare disease genetics
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
"The platform, called Mystra, named for the goddess of magic in the Forgotten Realms setting of the Dungeons & Dragons role-playing game"
Genomics Ltd Aims to De-Risk Drug Development With New AI-Enabled Biomarker, Drug Target Platform
www.genomeweb.com/biomarker-di...
Genomics Ltd Aims to De-Risk Drug Development With New AI-Enabled Biomarker, Drug Target Platform
www.genomeweb.com/biomarker-di...
a group of cartoon characters standing next to each other with the words what the dm doin '
ALT: a group of cartoon characters standing next to each other with the words what the dm doin '
media.tenor.com
October 17, 2025 at 11:50 AM
"The platform, called Mystra, named for the goddess of magic in the Forgotten Realms setting of the Dungeons & Dragons role-playing game"
Genomics Ltd Aims to De-Risk Drug Development With New AI-Enabled Biomarker, Drug Target Platform
www.genomeweb.com/biomarker-di...
Genomics Ltd Aims to De-Risk Drug Development With New AI-Enabled Biomarker, Drug Target Platform
www.genomeweb.com/biomarker-di...
Reposted by Kahlil Lawless
Just FYI if you are not familiar with Academia, it is at least 50% this
October 16, 2025 at 2:25 PM
Just FYI if you are not familiar with Academia, it is at least 50% this
Reposted by Kahlil Lawless
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 15, 2025 at 12:22 PM
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 16, 2025 at 11:53 AM
Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health
Nice new work from the UK Biobank
www.nature.com/articles/s41...
Nice new work from the UK Biobank
www.nature.com/articles/s41...
Client Challenge
www.nature.com
October 14, 2025 at 12:38 PM
Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health
Nice new work from the UK Biobank
www.nature.com/articles/s41...
Nice new work from the UK Biobank
www.nature.com/articles/s41...
I tried to retrain a MS CoPilot agent, playfully named it Igor to my Dr Frankenstein, asked it to call me "Master", and BOY did MS shut me down so fast... It errored out, complained, crashed, and then they would not let me delete it. Some forensic analyst must now be poring over its seizured code...
October 11, 2025 at 6:33 PM
I tried to retrain a MS CoPilot agent, playfully named it Igor to my Dr Frankenstein, asked it to call me "Master", and BOY did MS shut me down so fast... It errored out, complained, crashed, and then they would not let me delete it. Some forensic analyst must now be poring over its seizured code...
Frankfurt airport is almost comically German, with everyone wandering around with steins of beer, pretzels, and sausages
October 11, 2025 at 6:21 PM
Frankfurt airport is almost comically German, with everyone wandering around with steins of beer, pretzels, and sausages
Reposted by Kahlil Lawless
15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵
October 10, 2025 at 4:47 PM
15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵
My colleagues in the new Bio-Insight division kicking goals. Pharma are an unexpected force in the diversification of ethnicities in genomic research.
Illumina-led Consortium Draws Interest From Pharma Companies Seeking Diverse Genomes
www.genomeweb.com/business-new...
Illumina-led Consortium Draws Interest From Pharma Companies Seeking Diverse Genomes
www.genomeweb.com/business-new...
Illumina-led Consortium Draws Interest From Pharma Companies Seeking Diverse Genomes
The Alliance for Genomic Discovery offers a peek at what it looks like when Illumina controls all aspects of generating genomic — and soon, multiomic — data.
www.genomeweb.com
October 11, 2025 at 6:03 PM
My colleagues in the new Bio-Insight division kicking goals. Pharma are an unexpected force in the diversification of ethnicities in genomic research.
Illumina-led Consortium Draws Interest From Pharma Companies Seeking Diverse Genomes
www.genomeweb.com/business-new...
Illumina-led Consortium Draws Interest From Pharma Companies Seeking Diverse Genomes
www.genomeweb.com/business-new...
Benchmarking performance across HTS systems
sapac.illumina.com/science/geno...
sapac.illumina.com/science/geno...
Ultima Genomics UG 100 platform vs. Illumina NovaSeq X Series whole-genome sequencing benchmarking
In 2024, Ultima Genomics launched the UG 100 sequencing platform with bold performance and accuracy claims. To evaluate these claims, Illumina conducted a comparative analysis of the NovaSeq X Series ...
sapac.illumina.com
October 10, 2025 at 2:12 PM
Benchmarking performance across HTS systems
sapac.illumina.com/science/geno...
sapac.illumina.com/science/geno...
Thank you @ga4gh.org - our pleasure!
We want to thank Illumina for being a Supporting Funder of GA4GH and a Silver Sponsor of the GA4GH 13th Plenary meeting. Thank you for your commitment to GA4GH and supporting global collaborative genomic standards development.
October 8, 2025 at 1:11 PM
Thank you @ga4gh.org - our pleasure!