Honored to join @adamdourson.bsky.social and brilliant colleagues for an insightful discussion about immune system's role in chronic pain. Great exchange of ideas with @geoffroylaumey.bsky.social, Luda Diachenko, and Thiago Cunha! Listen here @iasp.bsky.social: www.iasp-pain.org/publications...

🔬 Exciting discovery! We've been curious about the function of unique IBA1+ cell staining we observed around healthy human DRG neurons in the lab (indicated by red arrows). A new paper @cellpress.bsky.social finally provides some answers. Link: www.cell.com/cell/fulltex...

Our latest research with Prof. Zhang is out in @cp-neuron.bsky.social. We've uncovered how blood vessel motion in sensory ganglia triggers spontaneous pain through Piezo2. Our findings open new therapeutic possibilities for treating episodic neuropathic pain. Link: www.cell.com/neuron/fullt...

Excited to share our latest findings with Dr. Park's team @Gachon University! We've uncovered how amyloid beta modulates heat pain sensitivity via the LRP1-SHP2 pathway in DRG neurons. This could open new therapeutic avenues for age-related chronic pain. Read more: pubmed.ncbi.nlm.nih.gov/40054577/

Proud to be part of this exciting study from our fantastic collaborator Prof. Chul-Kyu Park (Gachon University) about how the transcription factors Ascl1 and Lhx6 could help treat diabetic neuropathic pain by modulating GABAergic peripheral neurons. Link: pubmed.ncbi.nlm.nih.gov/39741412/

Excited to share a press release from @leedsunimedia.bsky.social about our joint work with Drs. Gamper and Du. Our body produces its own "sleeping pills" to control pain signals -a new non-opioid pain treatment? #SatelliteGlialCells #NIH_HEALinitiative Read more: www.leeds.ac.uk/main-index/n...

Out of curiosity, I used @notion.com and Napkin AI to visualize the first chapter of my upcoming review on satellite glial cells and chronic pain. The graphical summary turned out quite well, though you'll need to read the full review when it's published for all the details ;-) #SatelliteGlialCells

6/6 Translational research is one of our priorities, partially inspired by Drs. Price @tedpricethepainguy.bsky.social and Dougherty's work characterizing neuropathic pain in human dorsal root ganglion neurons - a great example of this research's potential impact. pubmed.ncbi.nlm.nih.gov/30887021/

5/6 Together with my postdoctoral work on resolvins and pain, Dr. Kavelaars's publication on CD8 T-cells' contribution to pain progression has shaped our research on how immune cells aid pain resolution - the focus of our new HEAL initiative grant (NS136108). pubmed.ncbi.nlm.nih.gov/27798187/

4/6 Since the beginning of our lab in 2016, we've had a keen eye for cellular heterogeneity and various methods to study it, thanks to the seminal work from Dr. Ernfors's lab @patrikernfors.bsky.social. pubmed.ncbi.nlm.nih.gov/25420068/

3/6 While our lab focuses on non-neuronal pain mechanisms, we also study sensory neurons and pain resolution. Our recent work shows DJ-1/PARK7 regulates neuronal excitability in mouse and human models, suggesting potential neuropathy treatments. pubmed.ncbi.nlm.nih.gov/39486088/

2/6 We are also interested in sex-specific effects in chronic pain. Our findings reveal interferon-signaling microglia can reduce established neuropathic pain in male mice, but not females. pubmed.ncbi.nlm.nih.gov/38190983/

1/6 First, we are a highly collaborative lab interested in non-neuronal cell contributions to chronic pain, such as the role of satellite glial cells in neuronal health and pain mechanisms. Grateful for amazing collaborations with Drs. Gamper (UK) and Du (China). pubmed.ncbi.nlm.nih.gov/38888973/

Thrilled to join the vibrant neuroscience community on @bsky.app ! Looking forward to sharing insights and discussing groundbreaking research. For my lab introduction, I'll share a thread showcasing three of our recent publications and three studies that have greatly inspired our work ...