The Daily Pub
@thedailypub.bsky.social
140 followers 620 following 3K posts
Posting bioinformatics-related publications daily Sourced from PubMed: https://pubmed.ncbi.nlm.nih.gov/ A product of MAB: https://midauthorbio.com/ Follow us at: https://bsky.app/profile/midauthorbio.bsky.social
Posts Media Videos Starter Packs
thedailypub.bsky.social
Flavonoids are great for meds and cosmetics but tough to use due to solubility issues. This study shows E. coli W is a superstar in making flavonoids more usable by using sugar efficiently. It beats the standard lab E. coli K12 by handling flavonoids better. With tweaks, E. coli W ramps up produc...
Engineering a Robust Escherichia coli W Platform for Scalable Production of Flavonoid-O-Glucosides.
Published in Microbial biotechnology
doi.org
thedailypub.bsky.social
Reducing soil heavy metals just got a boost! Researchers developed a new material from iron tailings and sodium alginate that locks in toxic metals like lead, copper, and nickel in the soil, making them less harmful. It even tweaks the soil's bacterial balance and boosts plant growth. A promising...
Investigation of the modulation and co-stabilization mechanism on sodium alginate-modified ball-milled iron tailings on the deposition pathways of Pb(II), cu(II), Ni(II) in soil.
Published in International journal of biological macromolecules
doi.org
thedailypub.bsky.social
Scientists figured out a way to speed up plastic breakdown by evolving microbial communities. They ran experiments with bacteria on polyethylene, a tough plastic, as the sole food source. After 40 cycles, these microbes got better at creating biofilms, helping each other degrade the plastic more...
Synergistic biodegradation of polyethylene by experimentally evolved bacterial biofilms.
Published in The ISME journal
doi.org
thedailypub.bsky.social
Scientists explored the gut microbiome of a 936-year-old mummy dubbed the Zimapán man. Through advanced DNA techniques, they discovered typical human bacteria families and an abundance of the Clostridiaceae group, similar to other mummies. They also found Romboutsia hominis, a unique microbe not...
Microbiome characterization of a pre-Hispanic man from Zimapán, Mexico: Insights into ancient gut microbial communities.
Published in PloS one
doi.org
thedailypub.bsky.social
Babies in the womb get an immune crash course from their mothers! This clever system helps them not reject mom, all while gearing up for life outside. It's now thought that mom’s diet and microbes play a key role, preparing babies' immune systems for challenges like germs and allergens, potential...
A mother's touch: microbial guardians of early immune imprinting.
Published in Trends in immunology
doi.org
thedailypub.bsky.social
Surface soil fractures can worsen soil stability and speed up groundwater contamination by PFOA, a harmful chemical. Bigger fractures mean much faster PFOA spread. However, the introduction of a mix of microbes and minerals can slash contaminant levels significantly, especially in certain groundw...
Fracture-mediated transport and bio-mineral synergistic attenuation of PFOA plumes: Implications prediction for reactive remediation in heterogeneous field coupling with various groundwater environment.
Published in Journal of hazardous materials
doi.org
thedailypub.bsky.social
The study dives into how desert plants host specific bacteria and fungi on their leaves. By examining 734 leaf samples from Central Asia, it was uncovered that a plant's family ties and traits mainly determine the types of microbes present, more than the environment or location. Interestingly, fu...
Host phylogeny and traits shape the composition and network structure of the phyllosphere microbial communities in temperate desert plants.
Published in Microbiological research
doi.org
thedailypub.bsky.social
Researchers have cracked the secret codes of some plant-invading bad guys! By using advanced tech, they found that different pathogens, despite being unrelated by sequence, share similar 3D shapes to help them sneak past plant defenses. A particular discovery includes ankyrin proteins in some pat...
Structure-guided secretome analysis of gall-forming microbes offers insights into effector diversity and evolution.
Published in eLife
doi.org
thedailypub.bsky.social
Microbes play a big role in how organisms evolve, and their method of passing from one host to another can change this impact. Week and team created a model showing these effects depend on the host’s life history. This new approach helps us better grasp host-microbe relationships, offering a clea...
Digest: Theoretical advances in studying selection via microbiome-mediated traits.
Published in Evolution; international journal of organic evolution
doi.org
thedailypub.bsky.social
Yeast can now turn waste lipids into valuable chemicals more efficiently. By tweaking genes in Candida viswanathii and evolving its metabolism, researchers boosted production of a key compound called TAL by up to 50 times. This breakthrough offers a greener and cost-effective way to use waste fat...
Production of triacetic acid lactone from oleic acid by engineering the yeast Candida viswanathii.
Published in Microbial cell factories
doi.org
thedailypub.bsky.social
Bacteria swap genes like social networks swap memes, through mobile genetic elements (MGEs). These swaps can either boost or slow down bacterial evolution, depending on clashes between different MGEs and their hosts. This process impacts how microbes adapt, especially when facing challenges like...
Horizontal gene transfer, segregation loss, and the speed of microbial adaptation.
Published in Evolution letters
doi.org
thedailypub.bsky.social
Introducing MicroDFBEST, a breakthrough dual-function base editor for microbes that expands precise genome editing. It fuses powerful deaminases with a specialized Cas enzyme, allowing the widest editing window yet for microbial systems. This innovation paves the way for tweaking gene expression...
MicroDFBEST: A dCas12b-derived dual-function base editor with programmable editing characteristics for microbial genetic engineering.
Published in Synthetic and systems biotechnology
doi.org
thedailypub.bsky.social
Turns out, fungi have a fascinating party scene high up in the forest canopy! Different heights on trees and types of bryophytes (like mosses) impact fungal diversity. Living bryophytes host a vibrant fungal community, richer than dead ones. This research sheds light on the curious world of canop...
Canopy Height and Epiphytic Bryophytes Shape Fungal Communities in a Temperate Rainforest.
Published in Ecology and evolution
doi.org
thedailypub.bsky.social
Using bacteria for medical treatments is getting a sci-fi upgrade! Instead of traditional methods, scientists are exploring how to use bacteria's natural abilities to deliver drugs more safely and effectively. Imagine bacteria acting like tiny delivery bots, targeting diseases like cancer with le...
Repurposing the bacterial surface display technology for drug delivery.
Published in Advanced drug delivery reviews
doi.org
thedailypub.bsky.social
Researchers explored how to tackle algae blooms in urban rivers using natural processes. They found sulfur-driven denitrification and anammox to be more effective when combined. Adding calcium nitrate improved nitrogen removal by up to 93.89%. Key players like Thiobacillus shone, showing promise...
Comparison of sulfur cyclings coupled with anaerobic ammonium oxidation in response to different river remediations.
Published in Journal of environmental management
doi.org
thedailypub.bsky.social
Pharmaceutically Active Compounds (PhACs) can build up on farmlands from human activities, potentially disturbing ecosystems. An experiment showed that soil microbes break down organic matter, reducing its ability to hold PhACs. Initially, certain chemical properties of PhACs were key in how they...
Soil organic matter decomposition as a key driver of pharmaceutical retention.
Published in Journal of environmental management
doi.org
thedailypub.bsky.social
E. coli just got cooler—or hotter, rather! Scientists pushed these bacteria to thrive at 45.3°C, a normally deadly heat for them. Key to survival? They fine-tuned stress responses, tapped into anaerobic metabolism, and relied on new heat-fighting genes. Understanding these tweaks could unlock sec...
Laboratory Evolution Reveals Transcriptional Mechanisms Underlying Thermal Adaptation of Escherichia coli.
Published in Genome biology and evolution
doi.org
thedailypub.bsky.social
Vineyards shake up the environment, creating a playground for microbes. A study of over 4,000 yeast strains found that while many vineyard yeasts also hang out in nearby trees, only *Saccharomyces cerevisiae* has developed superpowers to resist common vineyard chemicals, making it a unique vineya...
Colonization of vineyards by non- Saccharomyces yeast species without evolution of copper and sulfite resistance.
Published in bioRxiv : the preprint server for biology
doi.org
thedailypub.bsky.social
Research from 1995 to 2025 shows drought stress is a big problem for ornamental plants. Fewer studies focus on them compared to crops, but interest is growing in understanding their response. Top studies cover plant gas exchange, photosynthesis, and molecular-level changes. Despite some internati...
Blossoms amid drought: a bibliometric mapping of research on drought stress in ornamental plants (1995-2025).
Published in Frontiers in plant science
doi.org
thedailypub.bsky.social
Rising antibiotic resistance is a huge issue, but mixing silver nanoparticles with chiral antibiotics might be making things worse, especially in wastewater. A new study shows that silver nanoparticles can change how bacteria resist antibiotics by boosting resistance gene exchange and affecting b...
Enantioselective interactions of silver nanoparticles and chiral antibiotics in driving resistance evolution in activated sludge.
Published in Water research
doi.org
thedailypub.bsky.social
Imagine a world where bacteria help fight cancer and infections! Scientists are using naturally occurring sugars from bacteria to make tiny, eco-friendly particles that could revolutionize the way we treat diseases. These nanoparticles, made from metals like silver and gold, are effective against...
Advances in metal nanofabrication using microbial exopolysaccharides: Emerging biomedical applications.
Published in International journal of pharmaceutics
doi.org
thedailypub.bsky.social
This study dives deep into the soil and water below our feet, revealing that pollutants like PFAS and CAHs significantly affect the tiny microbial communities. In soil, bugs like Bacillus thrive, whereas in groundwater, Oxalobacteraceae flourish. Intriguingly, groundwater pollution impacts these...
Effects of concurrent PFASs and CAHs on microbial communities in soil and groundwater: an insight for their ecological niches and implications for bioremediation.
Published in Environmental pollution (Barking, Essex : 1987)
doi.org
thedailypub.bsky.social
Baby guts are fascinating! The study found that C-section babies had more DNA swaps between gut bacteria at birth than those born vaginally, but it evened out by two months. For vaginal births, these swaps boosted genes tied to sugar processing and immunity, while C-sections saw increases in meta...
Horizontal gene transfers differentially shape the functional potential of the infant gut metagenome.
Published in Life sciences
doi.org
thedailypub.bsky.social
East China sika deer have a genius way of adapting to the seasons. In summer, they munch on a wide variety of plants, while in winter, they focus on fewer, more specialized options. This switch helps them keep their diet balanced all year. Clever gut microbes team up with the deer to enhance thei...
Diet, nutrient characteristics and gut microbiome between summer and winter drive adaptive strategies of East China sika deer (Cervus nippon kopschi) in the Yangtze River basin.
Published in BMC microbiology
doi.org
thedailypub.bsky.social
Imagine turning sludge into something useful with heat-loving microbes! These microbes help break down sludge by heating it up over 65°C, which shrinks particles and loosens up its structure. Water trapped in the sludge is cleverly moved and turned into vapor. Thanks to these microbes, moisture l...
Mechanistic insights into the sludge biodrying process: the evolution of sludge structure and microbial community.
Published in Environmental technology
doi.org