Hope Welhaven, PhD
@thehopefulscie1.bsky.social
180 followers 160 following 21 posts
PhD in Biochemistry | Postdoc UCSF ortho | #massspec meets #ortho | she/her
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Reposted by Hope Welhaven, PhD
bethanyandoko.bsky.social
In @JOrthopRes.bsky.social, the Christiansen Lab (UC Davis) reports sex differences in mice post-femur fracture:
🦴 Males show greater systemic bone loss & TNF-α elevation
💪 Females trend toward greater muscle loss in the injured limb
buff.ly/LfFQjGn
#ORSxDerby #ORSSMC
@ORSsociety.bsky.social
thehopefulscie1.bsky.social
@kelseyhcollins.bsky.social and I are kicking off the USASP Annual Scientific Meeting with a trip to the iconic Bean! Excited to be in Chicago, present my work this afternoon at poster B28, and join the Pain & Aging SIG tonight! 🎉

@usasp.bsky.social
thehopefulscie1.bsky.social
It’s out! Powerhouse team and a powerhouse paper with exciting and novel findings. Honored and proud to be part of this one - check it out! ⬇️🎉
kelseyhcollins.bsky.social
Excited to share the latest chapter of our work on fat-joint interorgan crosstalk in knee OA, featuring the role of complement factor D secreted by fat in knee pain. Link here: bit.ly/42Og5hJ

Thanks to @farsh-g.bsky.social for all of your support - @thehopefulscie1.bsky.social and all coauthors!
Reposted by Hope Welhaven, PhD
kelseyhcollins.bsky.social
Excited to share the latest chapter of our work on fat-joint interorgan crosstalk in knee OA, featuring the role of complement factor D secreted by fat in knee pain. Link here: bit.ly/42Og5hJ

Thanks to @farsh-g.bsky.social for all of your support - @thehopefulscie1.bsky.social and all coauthors!
Reposted by Hope Welhaven, PhD
cripple-vs-stem.bsky.social
#labdaptations alert🚨! This tube opener is great for individuals with limited hand strength/mobility or tremors. I use it to keep my joints from hyperextending/dislocating, which helps to decrease pain.
A sky blue tube rack contains a clear eppendorf tube. A teal gloved hand uses a dark blue lever to open the eppendorf tube with minimal force/strength.
Reposted by Hope Welhaven, PhD
satanikm.bsky.social
Many congratulations to the newly elected chairs @thehopefulscie1.bsky.social , @jackbroberts.bsky.social for GRS Cartilage 2027.. Great to see the GRS is in safe hands..
Reposted by Hope Welhaven, PhD
kelseyhcollins.bsky.social
Hey #CartilageGRS2025 trainees! Defending soon, looking for a postdoc, and/or want to live in beautiful San Francisco, CA? We're looking for motivated folks to solve complex puzzles involving systemic factors, fat, aging, the gut microbiome and MSK health. DMs open! @thehopefulscie1.bsky.social
thehopefulscie1.bsky.social
Feeling incredibly honored to be elected as a GRS Co-Chair AND to receive a podium award! Grateful for this opportunity to present some of our recent findings throughout the week and to be surrounded by such inspiring work and scientists at this conference 🎉
kelseyhcollins.bsky.social
Having lots of fun at #CartilageGRC2025 - Congrats to @thehopefulscie1.bsky.social on her election as the 2027 Cartilage GRS Co-Chair and her GRS Podium Award! Her work on aging and sex differences is awesome and so we are proud to share this work at the GRC meeting. Way to go, Hope! 🥂
Reposted by Hope Welhaven, PhD
kelseyhcollins.bsky.social
Excited for our workshop on interdisciplinary solutions to study mechanisms of musculoskeletal pain at #USASP2025 in Chicago, featuring talks from Nadeen Chahine, Hang Lin, Rachel Miller, and Allan Basbaum @usasp.bsky.social. #painresearch

Would love to see you there!
Reposted by Hope Welhaven, PhD
standupforscience.bsky.social
SO MANY STAND UP FOR SCIENCE EVENTS TO CHOOSE FROM—153 and COUNTING!

To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
List of Stand Up for Science events—official events in red, solidarity events in blue.
thehopefulscie1.bsky.social
Proud to be a scientist today and everyday. Science belongs to everyone and is for everyone ❤️🧬 #StandUpForScience
Reposted by Hope Welhaven, PhD
beebrookshire.bsky.social
At @standupforscience.bsky.social and the signs are statistically significantly excellent
A person in a mask holding a painting that says “hands off my transgenic mice”
Reposted by Hope Welhaven, PhD
plantnerd.bsky.social
🚨🧪 We’ve been talking to scientists at rallies today across the country in DC, Boston, Seattle, and NJ. Here’s why scientists are “Dismayed, depressed, disgusted” and what they’re doing about it

🧵 ⤵️ for more
#StandUpforScience #StandUpforScience2025
@nature.com
‘Scientists will not be silenced’: thousands protest Trump research cuts
Researchers at Stand Up for Science rallies voice defiance against the policies of US President Donald Trump’s administration.
www.nature.com
thehopefulscie1.bsky.social
#ORS2025 was one of the books! Loved sharing my science, volunteering at #ORSOpenDoor, seeing old friends and making new ones ❤️

See you next year in Charlotte, NC!
Reposted by Hope Welhaven, PhD
jasoncmarvin.bsky.social
Stellar presentation on student outcomes of the 2024 #ORSOpenDoor event by @mmcgeelawrence.bsky.social!

It was great to see how much the program has grown and thrived in its revival during her tenure as @orssociety.bsky.social Advocacy Council Chair.

Can’t wait to share 2025’s data with y’all!
A picture of Meghan at the podium for her talk entitled “Early Middle School Students are Highly Impressionable to Diversity-, General STEM-, and MSK Research-Related Awareness and Interests” during the ORS Annual Meeting.
Reposted by Hope Welhaven, PhD
dremilygoldberg.bsky.social
I am starting this morning by reaching outside of my science echo chamber (posting on facebook) to explain why the NIH matters and why the new indirect rate policy will be catastrophic to everyone
𝐖𝐡𝐚𝐭 𝐚𝐫𝐞 "𝐢𝐧𝐝𝐢𝐫𝐞𝐜𝐭𝐬"?
When I write a grant, I provide a budget of the estimated "direct" costs that it will take to complete the project. These direct costs include things like salaries (mine + my lab members), student tuition, lab supplies, computing, and specialized equipment. The "indirect" costs on NIH grants are added on top of this and they pay for things like building infrastructure, utilities (water, electricity, internet), and salaries of administrative support staff like people who help us submit the grants, safety personnel, and janitors. The description that NIH is subsidizing universities with indirects is false. These are costs that are essential to perform the research that the government has agreed to fund. Indirects are negotiated with the government ahead of time so these are mutually agreed upon numbers and can't be changed by universities (or the government) on a whim.
𝐖𝐡𝐚𝐭 𝐢𝐬 𝐭𝐡𝐞 𝐢𝐦𝐩𝐚𝐜𝐭 𝐨𝐟 𝐬𝐮𝐝𝐝𝐞𝐧𝐥𝐲 𝐥𝐨𝐰𝐞𝐫𝐢𝐧𝐠 𝐍𝐈𝐇 𝐢𝐧𝐝𝐢𝐫𝐞𝐜𝐭𝐬?
For this, I think some numbers are helpful. If I write a $100,000 grant, my institution's indirect rate is 62.5% so the university submits a total budget of $162,500 to the NIH for the project (100k for me, 62.5k for indirect costs). The new 15% rate is supposed to be effective immediately and applied to current grants (where we already agreed on the costs) such that suddenly instead of $62,500, the NIH will only pay the university $15,000. This will simply not cover the costs of actually performing the proposed research. Remember, the government set these indirect cost numbers - they were negotiated with universities that had to prove how this money is spent and follow very strict rules about what it can be used for. Let me be clear: these changes will destroy biomedical research in the US. 
𝐖𝐡𝐲 𝐬𝐡𝐨𝐮𝐥𝐝 𝐲𝐨𝐮 𝐜𝐚𝐫𝐞?
Most people are not scientists, so why should they care about research? Universities are often among the top employers in their cities. Even …
thehopefulscie1.bsky.social
Another amazing talk at #ORS2025 from @carolynchlebek.bsky.social !
👏🏼👏🏼

It was so fun to collaborate and bring #metabolomics into this well designed study centering around the effects of #obesity and weight loss on bone 🦴
thehopefulscie1.bsky.social
Starting #ORS2025 with a phenomenal talk from @sadewill.bsky.social on how #aging and the immune system alter and magnify IVD in both males and females, and more so, how #pain fits into this complex relationship 👏🏼🧬
Reposted by Hope Welhaven, PhD
kelseyhcollins.bsky.social
Hey @orssociety.bsky.social members! Are you at #ors2025? The board needs your feedback on the strategic plan. Please visit the focus groups in person today and tomorrow, or DM me for the QR code to submit feedback online.

Your voice matters!
thehopefulscie1.bsky.social
And that’s a wrap on #ORSOpenDoor!🎉🎉🎉

It was such a fun day for students, teachers, and volunteers. Huge thanks to our leaders @jasoncmarvin.bsky.social and Paula Hernandez, amazing volunteers, and @orssociety.bsky.social staff who made this event possible!
thehopefulscie1.bsky.social
The students had excellent questions for our awesome panel. One student asked “what is one piece of advice you would give us as middle schoolers?” We love Lance’s great piece of advice!
⬇️👂🏼

#ORSOpenDoor @orssociety.bsky.social
thehopefulscie1.bsky.social
Next up is @sadewill.bsky.social teaching us about the #spine, the immune system, and her journey in #ortho. She even put us all to the test guessing the animal based off their #skeleton 🦴🐴🐠

#ORSOpenDoor @orssociety.bsky.social
thehopefulscie1.bsky.social
@jasoncmarvin.bsky.social is our first speaker at #ORSOpenDoor educating us on #orthopaedics and #biomedical engineering! Importantly, Jason discussed that it is the only discipline to teach #equality in degrees earned with #women earning half of the bachelors degrees! 🏆
thehopefulscie1.bsky.social
Your #ORSOpenDoor 2025 volunteers!

We are so excited to engage students and teachers in short career talks, a discussion panel, and hands on workshops - it’ll be a fun day full of #stemoutreach! 🎉🧬🦴 @orssociety.bsky.social