@theidealhuman.bsky.social
which people do u follow?
December 11, 2024 at 7:26 PM
which people do u follow?
4) btw cell fusion has been used to fertilize an egg while preserving sperm organelles, which leads to surprising non DNA based inheritances with consequences
December 8, 2024 at 3:51 PM
4) btw cell fusion has been used to fertilize an egg while preserving sperm organelles, which leads to surprising non DNA based inheritances with consequences
3)
en.wikipedia.org/wiki/Hybrido...
Cell fusion has multiple roles in healthy humans, from organogenesis to tissue repair, and can be a advantage for tumors
pubmed.ncbi.nlm.nih.gov/27136533/
most cell to cell fusions instances in adulthood are unknown because the topic is unknown hence understudied
en.wikipedia.org/wiki/Hybrido...
Cell fusion has multiple roles in healthy humans, from organogenesis to tissue repair, and can be a advantage for tumors
pubmed.ncbi.nlm.nih.gov/27136533/
most cell to cell fusions instances in adulthood are unknown because the topic is unknown hence understudied
Hybridoma technology - Wikipedia
en.wikipedia.org
December 8, 2024 at 3:50 PM
3)
en.wikipedia.org/wiki/Hybrido...
Cell fusion has multiple roles in healthy humans, from organogenesis to tissue repair, and can be a advantage for tumors
pubmed.ncbi.nlm.nih.gov/27136533/
most cell to cell fusions instances in adulthood are unknown because the topic is unknown hence understudied
en.wikipedia.org/wiki/Hybrido...
Cell fusion has multiple roles in healthy humans, from organogenesis to tissue repair, and can be a advantage for tumors
pubmed.ncbi.nlm.nih.gov/27136533/
most cell to cell fusions instances in adulthood are unknown because the topic is unknown hence understudied
2) because this has permanent consequences (dna integration, organelles inheritance, etc)
Fusion can also be used in the lab to immortalize a cell that produce a given protein. Historically this has only been used for antibodies production, but in theory it could be used to produce any protein
Fusion can also be used in the lab to immortalize a cell that produce a given protein. Historically this has only been used for antibodies production, but in theory it could be used to produce any protein
December 8, 2024 at 3:46 PM
2) because this has permanent consequences (dna integration, organelles inheritance, etc)
Fusion can also be used in the lab to immortalize a cell that produce a given protein. Historically this has only been used for antibodies production, but in theory it could be used to produce any protein
Fusion can also be used in the lab to immortalize a cell that produce a given protein. Historically this has only been used for antibodies production, but in theory it could be used to produce any protein
Cell to cell fusion is distinct from tunnelling nanotube, extracellular vesicles and endocytosis exchanges of material between cells. (I am not familiar with tunnelling nanotube research btw)
Cells do fuse together, the actual rate and relevance is unknown but probably relevant because
Cells do fuse together, the actual rate and relevance is unknown but probably relevant because
December 8, 2024 at 3:44 PM
Cell to cell fusion is distinct from tunnelling nanotube, extracellular vesicles and endocytosis exchanges of material between cells. (I am not familiar with tunnelling nanotube research btw)
Cells do fuse together, the actual rate and relevance is unknown but probably relevant because
Cells do fuse together, the actual rate and relevance is unknown but probably relevant because
there is also the understudied question of cell to cell fusion
December 8, 2024 at 3:20 PM
there is also the understudied question of cell to cell fusion
That's kinda the plot of this horror manga:
www.instagram.com/manga.tetsu/...
www.instagram.com/manga.tetsu/...
Tetsu on Instagram: "𝗧𝗵𝗲 𝗯𝗶𝘁𝘁𝗲𝗿𝘀𝘄𝗲𝗲𝘁 𝗲𝗻𝗱𝗶𝗻𝗴 𝗼𝗳 𝗨𝘇𝘂𝗺𝗮𝗸𝗶
Manga: Uzumaki
You all know I'm a big fan of Junji Ito's work. But Uzumaki surpass every other horror manga I've ever read. Especially the dist...
770 likes, 16 comments - manga.tetsu on October 26, 2023: "𝗧𝗵𝗲 𝗯𝗶𝘁𝘁𝗲𝗿𝘀𝘄𝗲𝗲𝘁 𝗲𝗻𝗱𝗶𝗻𝗴 𝗼𝗳 𝗨𝘇𝘂𝗺𝗮𝗸𝗶
Manga: Uzumaki
You all know I'm a big fan of Junji Ito's work. But Uzumaki surpass every other horror man...
www.instagram.com
November 28, 2024 at 10:59 PM
That's kinda the plot of this horror manga:
www.instagram.com/manga.tetsu/...
www.instagram.com/manga.tetsu/...
The most potent T cell upregulator is thymalin btw
November 28, 2024 at 12:38 AM
The most potent T cell upregulator is thymalin btw
global warming empirically shows a deficit in raining globally
November 26, 2024 at 1:27 AM
global warming empirically shows a deficit in raining globally
While the beta lactam selectivity in theory should make beta lactams have low eukaryotic cytotoxicity, in practice for unclear reasons that is far from the case. Beta lactams induce significant oxidative stress which is lower in some other classes.
BTW humans have beta lactam proteins but niche role
BTW humans have beta lactam proteins but niche role
November 25, 2024 at 1:29 PM
While the beta lactam selectivity in theory should make beta lactams have low eukaryotic cytotoxicity, in practice for unclear reasons that is far from the case. Beta lactams induce significant oxidative stress which is lower in some other classes.
BTW humans have beta lactam proteins but niche role
BTW humans have beta lactam proteins but niche role
The field and translational state of antibiotic research is in a very poor state. It is criminal that nobody is attempting a dumb lipophillic version of fusidic acid in order to considerably improve cure rates AND reduce antibiotic resistance
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Reversing the Natural Drug Resistance of Gram-Negative Bacteria to Fusidic Acid via Forming Drug–Phospholipid Complex
Drug resistance substantially compromises antibiotic therapy and poses a serious threat to public health. Fusidic acid (FA) is commonly used to treat staphylococcal infections, such as pneumonia, oste...
pmc.ncbi.nlm.nih.gov
November 25, 2024 at 1:26 PM
The field and translational state of antibiotic research is in a very poor state. It is criminal that nobody is attempting a dumb lipophillic version of fusidic acid in order to considerably improve cure rates AND reduce antibiotic resistance
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
2) Also even if the universe is black per se, the total flux of light is 100% in excess of what is predicted
arxiv.org/abs/2203.11236
arxiv.org/abs/2203.11236
The cosmic optical background excess, dark matter, and line-intensity mapping
Recent studies using New Horizons LORRI images have returned the most precise measurement of the cosmic optical background to date, yielding a flux that exceeds that expected from deep galaxy counts b...
arxiv.org
November 24, 2024 at 12:14 PM
2) Also even if the universe is black per se, the total flux of light is 100% in excess of what is predicted
arxiv.org/abs/2203.11236
arxiv.org/abs/2203.11236
There are multiple alternative explanations to the olber paradox, the main one being tired light.
BTW the main competing expanding universe cosmology nowadays are rh=ct and coasting expansion
BTW the main competing expanding universe cosmology nowadays are rh=ct and coasting expansion
November 24, 2024 at 12:13 PM
There are multiple alternative explanations to the olber paradox, the main one being tired light.
BTW the main competing expanding universe cosmology nowadays are rh=ct and coasting expansion
BTW the main competing expanding universe cosmology nowadays are rh=ct and coasting expansion
how do those percentages compare to an equal weight loss induced through mere caloric restriction?
November 23, 2024 at 12:49 AM
how do those percentages compare to an equal weight loss induced through mere caloric restriction?
btw D-ribose is underatted in bioenergetics and even more so is the ultimate discovery of the century: Skq1
November 23, 2024 at 12:48 AM
btw D-ribose is underatted in bioenergetics and even more so is the ultimate discovery of the century: Skq1
the mitochondria fuel ratio research is a mess.
ALCAR is very interesting but so is its inhibitor: meldonium
wether improving glucose versus lipid oxidation is preferable is far from clear.
specifically for cardioproection meldonium should be better though
ALCAR is very interesting but so is its inhibitor: meldonium
wether improving glucose versus lipid oxidation is preferable is far from clear.
specifically for cardioproection meldonium should be better though
November 23, 2024 at 12:46 AM
the mitochondria fuel ratio research is a mess.
ALCAR is very interesting but so is its inhibitor: meldonium
wether improving glucose versus lipid oxidation is preferable is far from clear.
specifically for cardioproection meldonium should be better though
ALCAR is very interesting but so is its inhibitor: meldonium
wether improving glucose versus lipid oxidation is preferable is far from clear.
specifically for cardioproection meldonium should be better though
interesting!
November 23, 2024 at 12:43 AM
interesting!
hlahore.substack.com/p/48-x-more-...
vit d does not lower cardiac mortality but wonder if it does on emergencies
vit d does not lower cardiac mortality but wonder if it does on emergencies
4.8 times more likely to die within 28 days of entering ICU if low Vitamin D
4.8 X more likely to die within 28 days of ICU if low Vitamin D - Jan 2024
hlahore.substack.com
November 23, 2024 at 12:42 AM
hlahore.substack.com/p/48-x-more-...
vit d does not lower cardiac mortality but wonder if it does on emergencies
vit d does not lower cardiac mortality but wonder if it does on emergencies
Vitamin D does not reduce CV mortality but does reduce all cause mortality
pubmed.ncbi.nlm.nih.gov/37111028/
moreover those trials are limited by their durations, some effects even if rare, can accumulate over the whole lifespan
pubmed.ncbi.nlm.nih.gov/37111028/
moreover those trials are limited by their durations, some effects even if rare, can accumulate over the whole lifespan
Vitamin D Supplementation and Its Impact on Mortality and Cardiovascular Outcomes: Systematic Review and Meta-Analysis of 80 Randomized Clinical Trials - PubMed
The emerging results of our meta-analysis present evidence that vitamin D supplementation appears to decrease the risk of ACM (especially convincing in the fair- and good-quality RCTs), while not show...
pubmed.ncbi.nlm.nih.gov
November 23, 2024 at 12:38 AM
Vitamin D does not reduce CV mortality but does reduce all cause mortality
pubmed.ncbi.nlm.nih.gov/37111028/
moreover those trials are limited by their durations, some effects even if rare, can accumulate over the whole lifespan
pubmed.ncbi.nlm.nih.gov/37111028/
moreover those trials are limited by their durations, some effects even if rare, can accumulate over the whole lifespan
there are countless benefits of vitamin D
vitamindwiki.com
vitamindwiki.com
VitaminDWiki | VitaminDWiki
Science-based Vitamin D
vitamindwiki.com
November 23, 2024 at 12:34 AM
there are countless benefits of vitamin D
vitamindwiki.com
vitamindwiki.com
iirc SLGT2i are better here
November 23, 2024 at 12:26 AM
iirc SLGT2i are better here
the insane cost-benefit of glp1 to society must be compared to alternatives such as pubmed.ncbi.nlm.nih.gov/29641571/
Still reduced cardiovascular mortality 12 years after supplementation with selenium and coenzyme Q10 for four years: A validation of previous 10-year follow-up results of a prospective randomized doub...
Clinicaltrials.gov NCT01443780.
pubmed.ncbi.nlm.nih.gov
November 23, 2024 at 12:26 AM
the insane cost-benefit of glp1 to society must be compared to alternatives such as pubmed.ncbi.nlm.nih.gov/29641571/
RCTs are often inferior to observational studies, it is not intuitive but well eplained in the literature
November 23, 2024 at 12:22 AM
RCTs are often inferior to observational studies, it is not intuitive but well eplained in the literature
Extremely interesting, I wonder if this included neurofilament light chain.
BTW you might be interested in this study pubmed.ncbi.nlm.nih.gov/29641571/
BTW you might be interested in this study pubmed.ncbi.nlm.nih.gov/29641571/
Still reduced cardiovascular mortality 12 years after supplementation with selenium and coenzyme Q10 for four years: A validation of previous 10-year follow-up results of a prospective randomized doub...
Clinicaltrials.gov NCT01443780.
pubmed.ncbi.nlm.nih.gov
November 23, 2024 at 12:19 AM
Extremely interesting, I wonder if this included neurofilament light chain.
BTW you might be interested in this study pubmed.ncbi.nlm.nih.gov/29641571/
BTW you might be interested in this study pubmed.ncbi.nlm.nih.gov/29641571/
There was a recent study though about cardiac atrophy.
BTW here is one of the most interesting study in cardiology pubmed.ncbi.nlm.nih.gov/29641571/
BTW here is one of the most interesting study in cardiology pubmed.ncbi.nlm.nih.gov/29641571/
Still reduced cardiovascular mortality 12 years after supplementation with selenium and coenzyme Q10 for four years: A validation of previous 10-year follow-up results of a prospective randomized doub...
Clinicaltrials.gov NCT01443780.
pubmed.ncbi.nlm.nih.gov
November 23, 2024 at 12:14 AM
There was a recent study though about cardiac atrophy.
BTW here is one of the most interesting study in cardiology pubmed.ncbi.nlm.nih.gov/29641571/
BTW here is one of the most interesting study in cardiology pubmed.ncbi.nlm.nih.gov/29641571/