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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 5d

We’ve reached 319 participants in the BIGKiDs Study! 🎉 Each participant brings us closer to unlocking answers for nephrotic syndrome. Thank you for being part of the journey! 💙🧬
💙Be part of the discovery ➡️ buff.ly/DxYs1qw

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 7d

Meet Victoria!
Victoria joins us from Heidelberg University, Germany, where she studied Mathematics with a thesis in high-dimensional statistics applied to medical research. As a Visiting Researcher in the Lab, Victoria is investigating the genetic causes of nephrotic syndrome!🧬 💙

Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 25d

✨ This week’s team meeting had a new twist. Our newest members took the spotlight! Choah, Victoria, and Beomsu shared a few slides about their backgrounds, interests, and hobbies, giving us a chance to get to know them beyond the lab bench. We’re excited to have them on board!!

Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 26d

Nephrotic syndrome doesn’t just cause swelling; it can lead to infections, blood clots, kidney damage, and many other complications. 💧🩸🦠

📌 Learn more about our research and how you can support families affected by kidney disease at the link in our bio. #nephrology #genomics

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 28d

The Sampson Lab is growing! We’re thrilled to welcome new faces to the team! Keep an eye on our socials as we spotlight each of them and share the exciting projects they’ll be diving into. Big things are ahead, and we can’t wait to share the journey with you! 💙🔬

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Sep 5

Ever Googled “What is the Sampson Lab doing?” 👀 We’ve got the answers ready for you. ➡️ Swipe through to learn more! #SampsonLab #BIGKiDsStudy #howrareisrare #NephroticSyndrome #KidneyHealth #RareDiseaseResearch #PediatricNephrology #sampsonlab #BIGKiDs

Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Sep 2

💌 A little note from Sampson Lab 💙
Sometimes we all need a gentle nudge: 👉 Which reminder did you need today? Share it in the comments! #nephrology #genomics #kidneyomics #pediatrics #pediatricnephrology #nephroticsyndrome

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Aug 29

🔎 Ever Googled “What does the Sampson Lab actually do?” You’re not alone; these are the BIG questions we hear all the time.
At the Sampson Lab, we’re on a mission to:
✨ Discover genetic causes of nephrotic syndrome
✨ Bring precision medicine closer to children around the world

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Aug 26

⏰ Today’s Reminder from Sampson Lab
You can still join the BIGKiDs Study! 💙
Your participation helps us uncover the genetic causes of nephrotic syndrome and move closer to better treatments for kids worldwide. 👉 Sign up through the link in bio.

Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Aug 20

🩵 Nephrotic syndrome can look very different in kids vs. adults. 📊 Understanding these differences is key to early detection and better care.#KidneyHealth #NephroticSyndrome #PediatricCare #Nephrology #sampsonlab #raredisease

Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Aug 18

Congratulations to Kristen Gibson, a post-doctoral fellow in our lab, for two recent awards from the Canadian Kidney Research Scientist Core Education and National Training Program and the Children’s Hospital of Philadephia Pediatric Center of Excellence in Nephrology Program! Go Kristen!

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Aug 15

Your kidneys filter 50 gallons of blood every single day. Drinking enough water helps support kidney function and reduce the risk of kidney stones and other complications. So yes, staying hydrated? It’s a love letter to your kidneys.#sampsonlab #kidneyhelalth #nephrology

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Aug 13

Dr. Sampson’s lab is leading the Data Science curriculum for research fellows who are part of the NIH Training Grant. Michelle McNulty and Kristen Gibson are kicking it off with a two-class series on the fundamentals of R. It’s so exciting that even Dr. Bonventre is taking it!

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Aug 11

Not all research studies mean lab coats and hospital visits. Some start with a simple question... and a shipping label.

💡 Think you need to live in Boston to participate?
💡 Think research is only for scientists?

🔗 Learn more at www.sampsonlab/getinvolved.com

Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Aug 4

What is nephrotic syndrome, and what’s actually causing it? Nephrotic syndrome isn’t one disease; it’s a group of symptoms caused by damage to the kidney’s filters. Follow along as we break down the most common root causes of nephrotic syndrome one post at a time. #nephroticsyndrome #sampsonlab

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Aug 1

The first 4–6 weeks of treatment help doctors understand how a child’s body is responding to steroids. This early response helps determine if the nephrotic syndrome is steroid-sensitive or steroid-resistant, a key step in guiding next steps for care.

Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Aug 1

On Tuesday, we had the pleasure of hearing Dr. Dongwon Lee, Principal Investigator, share his experience at the 2025 Gordon Research Conference on Human Genetics and Genomics in Portland, ME. We’re always proud to see our team contributing to such impactful scientific spaces!

Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Jul 30

The line between MCD and FSGS isn’t always obvious. Both can cause nephrotic syndrome, but the body’s response to steroid treatment helps tell them apart. This is why treatment response and sometimes biopsy results are so important.
#NephroticSyndrome #sampsonlab #raredisease

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Jul 29

Today, our intern Aaheli gave her final presentation during lab meeting. It was great to see how she evaluated gene variants to help determine whether they were benign or pathogenic. We’ll miss her and wish her all the best as she begins her first semester at UMASS this fall!

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Jul 26

Last week, Dr. Dongwon Lee represented the lab at the 2025 Gordon Research Conference on Human Genetics and Genomics in Portland, Maine. This year’s theme focused on bridging gaps between statistical, molecular, and clinical genetics, something at the heart of our work.

Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Jul 25

Every trial, every study, every sample matters. Because behind the data, there are real people, real families, and real futures at stake.#research #raredisease #sampsonlab #genomics #MedicalResearch #ScienceToSolutions #BIGKiDsStudy #nephroticsyndrome #NephrologyResearch

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Jul 24

Your kidneys are working hard for you every day, every hour. Return the favor with these small habits that lead to lifelong health. 💬 Which of these do you already do? Which one could you start this week? #KidneyFacts #HealthyKidneys #NephrologyTips #BIGKiDsStudy #KidneyHealthAwareness #sampsonlab

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Jul 19

Our summer interns are finishing up at the end of July, and it's been great having them around the lab. From helping with current projects to fostering new collaborations, they've been a big part of the team these past few months. We'll miss having them around! #internship #summerintern #sampsonlab

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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Jul 15

We’re proud to team up with The Nephrotic Syndrome Foundation, a nonprofit supporting families impacted by nephrotic syndrome 💛 It’s a pleasure to stand alongside a mission so deeply rooted in empathy, advocacy, and action.

Get involved at nephroticsyndromefoundation.org

Nephrotic Syndrome Foundation

Working to support families and raise money to fight nephrotic syndrome

www.nephroticsyndromefoundation.org

Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · Jul 11

What lies beyond GWAS? 🧬
Last Wednesday Sidhant Puntambekar, computational biologist in the Sampson Lab gave a presentation breaking down the complexity of mapping mechanisms that go beyondunderlie pediatric steroid-sensitive nephrotic syndrome GWAS associations.#kidneyomics #RareDisease