T.T. Cooper
@ttcooper.bsky.social
Assistant Professor @ UdeM/CR-CHUM
Dad-of-4 Humans| Big Dogs 🐺
Coffee Addict☕
🇨🇦&🇺🇸
#SteelersNation
Scientist for Humanity👨🔬
Proteomics , EVs, and Machine Learning 🔬
thecooperlab.com
Dad-of-4 Humans| Big Dogs 🐺
Coffee Addict☕
🇨🇦&🇺🇸
#SteelersNation
Scientist for Humanity👨🔬
Proteomics , EVs, and Machine Learning 🔬
thecooperlab.com
Reposted by T.T. Cooper
I've been very impressed with the Ceres Nano-Trap enrichment beads so far. www.ceresnano.com/nanotrap-peak . I just quantified over 2200 proteins from Dog Plasma. Including reliably seeing KITLG (Stem Cell Factor) which is in the pg/ml range I think. Let's see O-link do that in in dog ...Pfft.
Nanotrap Protein Enrichment Affinity Kit | Ceres Nano
Nanotrap® Protein Enrichment Affinity Kits (PEAK) use the Nanotrap hydrogel particle technology to capture and concentrate low abundance, low molecular weight proteins and peptides while simultaneousl...
www.ceresnano.com
December 4, 2025 at 6:17 PM
I've been very impressed with the Ceres Nano-Trap enrichment beads so far. www.ceresnano.com/nanotrap-peak . I just quantified over 2200 proteins from Dog Plasma. Including reliably seeing KITLG (Stem Cell Factor) which is in the pg/ml range I think. Let's see O-link do that in in dog ...Pfft.
If our research doesn't interest you, I know our view from the graduate student desks will.
December 4, 2025 at 3:19 PM
If our research doesn't interest you, I know our view from the graduate student desks will.
You`re giving me PTSD from our first year with the Neo Vanquish. If you run auto-startup script with diagnostics in direct inject mode it has more verbose.
December 4, 2025 at 3:06 PM
You`re giving me PTSD from our first year with the Neo Vanquish. If you run auto-startup script with diagnostics in direct inject mode it has more verbose.
Just recieved 3 quotes from 3 different mass spec vendors.... let the games begin.
December 4, 2025 at 3:03 PM
Just recieved 3 quotes from 3 different mass spec vendors.... let the games begin.
Looking for students who are interested in the intersection of molecular biology and mass spectometry. Bioinformatic students, please consider applying, we are happy provide hands-on cell biology training. Biology or Biochemistry students, this is your chance to gain hands-on multi-omics experience.
🚀 Two MSc opportunities at CR-CHUM!
Join our lab to study:
🔬 Early-stage ovarian cancer biomarkers
🧬 EV-mediated communication in the tumour microenvironment
Offered through UdeM (Biologie moléculaire / Biochimie).
Start Jan/May.
DM or email: [email protected]
Join our lab to study:
🔬 Early-stage ovarian cancer biomarkers
🧬 EV-mediated communication in the tumour microenvironment
Offered through UdeM (Biologie moléculaire / Biochimie).
Start Jan/May.
DM or email: [email protected]
December 3, 2025 at 5:58 PM
Looking for students who are interested in the intersection of molecular biology and mass spectometry. Bioinformatic students, please consider applying, we are happy provide hands-on cell biology training. Biology or Biochemistry students, this is your chance to gain hands-on multi-omics experience.
Yay! After a month of waiting, my article finally has two reviewers who have agreed. Now time to wait another 1-2 months for review. 😅
December 2, 2025 at 5:28 PM
Yay! After a month of waiting, my article finally has two reviewers who have agreed. Now time to wait another 1-2 months for review. 😅
🚀 Two MSc opportunities at CR-CHUM!
Join our lab to study:
🔬 Early-stage ovarian cancer biomarkers
🧬 EV-mediated communication in the tumour microenvironment
Offered through UdeM (Biologie moléculaire / Biochimie).
Start Jan/May.
DM or email: [email protected]
Join our lab to study:
🔬 Early-stage ovarian cancer biomarkers
🧬 EV-mediated communication in the tumour microenvironment
Offered through UdeM (Biologie moléculaire / Biochimie).
Start Jan/May.
DM or email: [email protected]
December 2, 2025 at 5:27 PM
🚀 Two MSc opportunities at CR-CHUM!
Join our lab to study:
🔬 Early-stage ovarian cancer biomarkers
🧬 EV-mediated communication in the tumour microenvironment
Offered through UdeM (Biologie moléculaire / Biochimie).
Start Jan/May.
DM or email: [email protected]
Join our lab to study:
🔬 Early-stage ovarian cancer biomarkers
🧬 EV-mediated communication in the tumour microenvironment
Offered through UdeM (Biologie moléculaire / Biochimie).
Start Jan/May.
DM or email: [email protected]
I have 2 MSc positions in my lab. Please inquire for more information.
December 2, 2025 at 3:21 PM
I have 2 MSc positions in my lab. Please inquire for more information.
I am interviewing a research associate tomorrow and also teach a class. Is wearing a Halloween costume a no-no?
October 30, 2025 at 11:59 PM
I am interviewing a research associate tomorrow and also teach a class. Is wearing a Halloween costume a no-no?
Not sure if I get more email from predatory journals or my kids school. I almost need a seperate email just to keep up with the events and pizza days.
October 30, 2025 at 6:51 PM
Not sure if I get more email from predatory journals or my kids school. I almost need a seperate email just to keep up with the events and pizza days.
Right now, I have the issue of too many good candidates for one position. I wish I could hire them all. Any advice how to narrow it down at this point? Cost of salary vs time to train is what stands out.
October 29, 2025 at 3:33 PM
Right now, I have the issue of too many good candidates for one position. I wish I could hire them all. Any advice how to narrow it down at this point? Cost of salary vs time to train is what stands out.
I am still looking for a research coordinator or associate. Please contact me if interested.
October 21, 2025 at 10:03 AM
I am still looking for a research coordinator or associate. Please contact me if interested.
Hosting 12 interviews for the lab manager position in my laboratory. Does anyone have advice on what makes a great candidate? I am a new PI so the majority of applications are fresh out of school. I want to give some the benefit of the doubt without it becoming the "blind leading the blind" 😅
September 5, 2025 at 4:14 PM
Hosting 12 interviews for the lab manager position in my laboratory. Does anyone have advice on what makes a great candidate? I am a new PI so the majority of applications are fresh out of school. I want to give some the benefit of the doubt without it becoming the "blind leading the blind" 😅
#TeamMassSpec Does anyone have advice on manual pipette companies?
August 28, 2025 at 7:03 PM
#TeamMassSpec Does anyone have advice on manual pipette companies?
Proteomic review has been submitted. I won't tell you the topic yet 🙃
August 5, 2025 at 6:46 PM
Proteomic review has been submitted. I won't tell you the topic yet 🙃
First task as a new PI. Submitted my LOI for NSERC - Discovery Grant. 🥳
August 1, 2025 at 10:12 PM
First task as a new PI. Submitted my LOI for NSERC - Discovery Grant. 🥳
Job Posting – Research Assistant
Location: CR-CHUM
Supervisor: Dr. Tyler Cooper
Dr. Cooper’s lab at the CR-CHUM is recruiting a research technician or assistant to our team focusing on proteomics and cancer EVs.
If interested, please send your CV and cover letter to [email protected].
Location: CR-CHUM
Supervisor: Dr. Tyler Cooper
Dr. Cooper’s lab at the CR-CHUM is recruiting a research technician or assistant to our team focusing on proteomics and cancer EVs.
If interested, please send your CV and cover letter to [email protected].
August 1, 2025 at 2:28 PM
Job Posting – Research Assistant
Location: CR-CHUM
Supervisor: Dr. Tyler Cooper
Dr. Cooper’s lab at the CR-CHUM is recruiting a research technician or assistant to our team focusing on proteomics and cancer EVs.
If interested, please send your CV and cover letter to [email protected].
Location: CR-CHUM
Supervisor: Dr. Tyler Cooper
Dr. Cooper’s lab at the CR-CHUM is recruiting a research technician or assistant to our team focusing on proteomics and cancer EVs.
If interested, please send your CV and cover letter to [email protected].
Le laboratoire du Dr Tyler Cooper au CR-CHUM recrute un·e technicien·ne ou assistant·e de laboratoire motivé·e pour se joindre à une équipe dynamique spécialisée en protéomique et EVs.
Si ce poste vous intéresse, veuillez envoyer votre CV et lettre de motivation à [email protected].
Si ce poste vous intéresse, veuillez envoyer votre CV et lettre de motivation à [email protected].
August 1, 2025 at 2:22 PM
Le laboratoire du Dr Tyler Cooper au CR-CHUM recrute un·e technicien·ne ou assistant·e de laboratoire motivé·e pour se joindre à une équipe dynamique spécialisée en protéomique et EVs.
Si ce poste vous intéresse, veuillez envoyer votre CV et lettre de motivation à [email protected].
Si ce poste vous intéresse, veuillez envoyer votre CV et lettre de motivation à [email protected].
Off to the next chapter. It's been unreal.
July 31, 2025 at 2:55 PM
Off to the next chapter. It's been unreal.
This is me at 11pm, after kids in bed, 2 days from becoming an assistant professor. Last experiment of my postdoc. Working on last fist author during centrifuge steps. Publish or perish. It's been a ride.
July 30, 2025 at 2:58 AM
This is me at 11pm, after kids in bed, 2 days from becoming an assistant professor. Last experiment of my postdoc. Working on last fist author during centrifuge steps. Publish or perish. It's been a ride.
If you have been trying to reach me by my Queen's email, and I have not responded yet. Please DM me here.
July 24, 2025 at 10:32 AM
If you have been trying to reach me by my Queen's email, and I have not responded yet. Please DM me here.
Reposted by T.T. Cooper
🚀 Check out our preprint on the new Thermo Scientific Orbitrap Astral Zoom MS 💫👇🏼
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Higher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technolo...
www.biorxiv.org
July 19, 2025 at 9:22 AM
🚀 Check out our preprint on the new Thermo Scientific Orbitrap Astral Zoom MS 💫👇🏼
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Yay! Congrats to the authors.
The Mag-Net paper is out! We've now put 1000s of plasma samples through this protocol and we know others have too. We've used it to study dozens of diseases. Looking forward to seeing what others apply this towards. The preprint already has >39 citations. www.nature.com/articles/s41...
Enrichment of extracellular vesicles using Mag-Net for the analysis of the plasma proteome - Nature Communications
Authors report MagNet, a plasma extracellular vesicle (EV) enrichment strategy using magnetic beads. Proteomic interrogation of this plasma EV fraction enables the detection of proteins that are beyon...
www.nature.com
July 1, 2025 at 9:11 PM
Yay! Congrats to the authors.
Reposted by T.T. Cooper
Boosting Orbitrap MS/MS speed to ∼70 Hz? 🚀
Read how we did it in our latest paper 👇
pubs.acs.org/doi/10.1021/...
Read how we did it in our latest paper 👇
pubs.acs.org/doi/10.1021/...
Enhancing Tandem MS Sensitivity and Peptide Identification via Ion Preaccumulation in an Orbitrap Mass Spectrometer
High-throughput mass spectrometry-based proteomics has gained increasing interest for both academic and industrial applications. As implementation of faster gradients has facilitated higher sample thr...
pubs.acs.org
July 1, 2025 at 12:29 PM
Boosting Orbitrap MS/MS speed to ∼70 Hz? 🚀
Read how we did it in our latest paper 👇
pubs.acs.org/doi/10.1021/...
Read how we did it in our latest paper 👇
pubs.acs.org/doi/10.1021/...
