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Seychelle Vos
@voslab.org
· 19d
Seychelle Vos
@voslab.org
· Jul 19
Seychelle Vos
@voslab.org
· Apr 28
Seychelle Vos
@voslab.org
· Apr 26
Seychelle Vos
@voslab.org
· Mar 28
Reposted by Seychelle Vos
Seychelle Vos
@voslab.org
· Jan 1
The structural basis for RNA slicing by human Argonaute2
Mohamed et al. report the cryoelectron microscopy structure of human AGO2 with fully paired guide RNA. Their analysis reveals the structural basis for the slicing activity that drives RNAi, showing that the slicing-competent conformation is achieved by domain movements and RNA-protein contacts distinct from those of conformational intermediates and prokaryotic homologs.
tinyurl.com
Seychelle Vos
@voslab.org
· Dec 31