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@Westermarcklab @westermarcklab.bsky.social · 27d

#careergoals after all these years I was finally rewarded by a whiteboard in my office.😁 Had to start using it immediately.

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@Westermarcklab @westermarcklab.bsky.social · Aug 28

Elias Tillandz Prize awarded at the BioCity Symposium to scientific publications on breast cancer recurrence and cancer gene overactivation www.utu.fi/en/news/pres...

Elias Tillandz Prize awarded at the BioCity Symposium to scientific publications on breast cancer recurrence and cancer gene overactivation

The Elias Tillandz prize for the best scientific publication of 2024 was presented for two groundbreaking cancer studies.

www.utu.fi

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Reposted by @Westermarcklab

EMBO Molecular Medicine @embomolmed.org · Aug 11

August issue now online! ➡️ www.embopress.org/toc/17574684...
The cover highlights the study by X Qiao, J Routila, J Westermarck, S Ventelä & al @westermarcklab.bsky.social showing that LIMA1 detection can be used for #HNSCC patients stratification

Scientific image by M. Peltola, Thestra Oy, Turku

EMBO Molecular Medicine: Vol 17, No 8

EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.

www.embopress.org

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@Westermarcklab @westermarcklab.bsky.social · Aug 11

The beautiful image was taken by senior scientist Mari Peltola as part of Thestra´s R&D process to introduce the EPLINEx (the trade name for proprietary LIMA1 assay) IHC assay for clinical #HNSCC diagnostics.
Stay tuned: thestra.fi

Cancer diagnostics company | Thestra

We are a cancer diagnostics company which translates high quality academic research results to patient specific companion diagnostics and therapy stratification solutions.

thestra.fi

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@Westermarcklab @westermarcklab.bsky.social · Aug 11

We are on the cover! Or what is in the cover is way more important than we, it's evidence that simple IHC assay could be used for recognising #HNSCC patients based on their outcome after surgery-only therapy.
The actual cover and the article can be found here:
www.embopress.org/doi/full/10....

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@Westermarcklab @westermarcklab.bsky.social · Jul 23

The results are currently to be turned to a routine IHC diagnostic assay by our Start-up company Thestra Ltd. and we aim to bring the assay to clinical use by 2026.
Stay tuned!
thestra.fi/scientific-b...

Scientific background of Thestra´s EPLINEx™ method in HNSCC diagnosis reported in EMBO Molecular Medicine | Thestra

Scientific background of Thestra´s EPLINEx™ method is reported in EMBO Molecular Medicine, a leading medical journal.  The findings were validated across all Finnish university hospitals on the use of...

thestra.fi

@Westermarcklab @westermarcklab.bsky.social · Jul 23

Based on two prospective cohorts, none of the LIMA1-alpha negative HNSCC patients with non-metastatic disease upon diagnosis died during the follow-up.

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@Westermarcklab @westermarcklab.bsky.social · Jul 23

Particularly proud of this collaboration with Sami Ventela and all Finnish #HNSCC clinics revealing LIMA1-alpha as translatable biomarker for selection of HNSCC patients for surgery-only therapies.
www.utu.fi/en/news/pres...
www.embopress.org/doi/full/10....

New diagnostic breakthrough predicts which head and neck cancer patients can be cured with surgery alone

Researchers developed a diagnostic test based on the LIMA1-alpha protein to distinguish patients with head and neck squamous cell carcinoma who can be cured with surgery alone, without the need for

www.utu.fi

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@Westermarcklab @westermarcklab.bsky.social · Jul 22

Very nice bioinformatics analysis of the role of #CIP2A in ovarian cancer by @karteris.bsky.social
rdcu.be/exid3

Emerging roles of the cancerous inhibitor of protein phosphatase 2A (CIP2A) in ovarian cancer

Scientific Reports - Emerging roles of the cancerous inhibitor of protein phosphatase 2A (CIP2A) in ovarian cancer

rdcu.be

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@Westermarcklab @westermarcklab.bsky.social · Jun 26

Ps. Some PIs can brag about their 1 million € sequencers, I only got a 100€ sticker printer😅

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@Westermarcklab @westermarcklab.bsky.social · Jun 26

Lab cleaning day is one of the important @westermarcklab.bsky.social traditions. This year the after-cleaning pizzas were enjoyed in sunny Kupittaa park. Thanks Tiina for organization and everyone for your efforts

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Reposted by @Westermarcklab

Johanna Joyce @johannajoyce.bsky.social · Jun 23

Are you looking to start your #lab in a fantastic scientific 🧪environment, with great colleagues, and in a spectacular place to live?

Then check out our open #junior #faculty position at the Department of Oncology, University of Lausanne, Switzerland:
www.unil.ch/dof/en/home/...

⏰ Deadline 27 June

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Reposted by @Westermarcklab

EACR - European Association for Cancer Research @helloeacr.bsky.social · Jun 23

We’ve just marked a major milestone - our community of cancer researchers now numbers 14 000 members, working across 117 countries worldwide 🎉

Thank you to you, our members, for your ongoing support and commitment to advancing cancer research. Your passion and dedication inspire everything we do.

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@Westermarcklab @westermarcklab.bsky.social · Jun 18

Fantastic EACR @helloeacr.bsky.social annual congress in Lisbon. Great talks Great atmosphere Great to meet all old and new friends

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@Westermarcklab @westermarcklab.bsky.social · Jun 3

Lukijoilta | Tohtorintutkinto tulisi ottaa OKM:n ylimmän johdon pätevyysvaatimukseksi www.ts.fi/lukijoilta/6...

Lukijoilta | Tohtorintutkinto tulisi ottaa OKM:n ylimmän johdon pätevyysvaatimukseksi

OKM:n kansliapäällikön pätevyysvaatimusten korottaminen siten, että tiedepolitiikkaamme johdettaisiin vähintäänkin tohtoritutkinnon antaman tutkimuskokemuksen tuella, olisi mielipidekirjoittajien muka...

www.ts.fi

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@Westermarcklab @westermarcklab.bsky.social · Jun 2

Absolutely catapulting quadrable WEKK (Westermarck, Elenius, Kurppa, Kauko) retreat @Villa Wolax. Fantastic science, discussions, sauna, food, wine, colleagues @turkubioscience.bsky.social @medicity.bsky.social

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@Westermarcklab @westermarcklab.bsky.social · May 23

Stunning work! Huge Congrats @kusterlab.bsky.social

@Westermarcklab @westermarcklab.bsky.social · May 21

Want to relocate to Finland as a professor in the fields of basic, clinical, or translational medicine. An exciting funding opportunity. Please be on contact if I can be of any help.
www.sigridjuselius.fi/en/apurahat/...

Professorship (5 years) - Sigrid Jusélius Foundation

With the overall aim of supporting Finnish medical research to combat diseases that are devastating to humankind, the Sigrid Jusélius […]

www.sigridjuselius.fi

Reposted by @Westermarcklab

EACR - European Association for Cancer Research @helloeacr.bsky.social · May 20

Early-stage, curiosity-driven cancer research is the cornerstone of future medical breakthroughs. Let's #KeepResearchCurious ✨

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@Westermarcklab @westermarcklab.bsky.social · May 20

Thanks Guillaume for your very valuable contribution.

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@Westermarcklab @westermarcklab.bsky.social · May 18

The work involves very important contributions from several collaborating laboratories of Saverio Minucci, Andrea Mattevi, Matti Nykter, guillaume Jacquemet, Otto Kauko, Tiziana Bonaldi and others. You can also listen the main conclusions: sciencecast.org/casts/51duqt...

Science Cast

Increase your recognition in the scientific world with short video-casts

sciencecast.org

@Westermarcklab @westermarcklab.bsky.social · May 18

The results both solve the longstanding enigma how LSD1 can function in gene activation in non-hormonal cancers but more generally demonstratehow a single phosphorylation site in a non-histone protein can control epigenetic landscape and thereby shape even tumour immune microenvironment.

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@Westermarcklab @westermarcklab.bsky.social · May 18

New preprint from us.
The study led by Mukund Sharma demonstrates how #PP2A mediated dephosphorylation of serine 166 of LSD1 functions as a phosphorylation switch between gene repression and activation by LSD1 and how this shapes tumor microenvironment.
www.biorxiv.org/content/10.1...

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@Westermarcklab @westermarcklab.bsky.social · May 16

Very exciting program for the next year @helloeacr.bsky.social "Signaling Circuits in Cancer" virtual meeting just published.

Scientific programme | Signalling Circuits in Cancer | The European Association for Cancer Research url:https://eacr.org/conference/signallingcircuits2026/sc

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