Andrew Urquhart
wolfeagle1989.bsky.social
Andrew Urquhart
@wolfeagle1989.bsky.social
PhD in Space Physics. Hobbyist SARS-CoV-2 lineage hunter. I will block trolls, misinformers, and disinformers at my personal discretion.
Major US airports in Denver and Newark were previously reported as impacted by the US Government shutdown. Houston is now expected to be added to the list. www.khou.com/article/news....
Government shutdown to impact travelers at both Houston airports, FAA website shows
Traveling soon? Get ready to start feeling the impact of the federal government shutdown at Houston airports.
www.khou.com
October 7, 2025 at 8:15 PM
Oops. I found a typo in the second post. Correct “TRS-B was is found” to “TRS-B is found”.

I’ll also note that few B.1.1 with N:G204P, especially KP.3.3, actually have the N* TRS-B broken. So *all* B.1.1 having the N* TRS-B is an overstatement. But most B.1.1 do have it. (4/3)
August 26, 2025 at 3:58 AM
More on N.iORF3 aka N*M210 aka N* can be found in Mears et al doi.org/10.1371/jour... and the Mulloy et al preprint doi.org/10.1101/2025.... Enhanced transcription of this protein may enhance XFG fitness. (3/3)
Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion
Coronaviruses can evolve novel transcription regulatory sequences, generating new RNA transcripts during human infection. This study identifies a prevalent subgenomic RNA in SARS-CoV-2, which produces...
doi.org
August 26, 2025 at 3:49 AM
These mutations were previously seen in Gamma (P.1). The base N.iORF3 aka N*M210 aka N* TRS-B was is found in all B.1.1 including Alpha, Gamma, and Omicron, and this protein is known to enhance SARS-CoV-2 fitness including through innate immune evasion. (2/3)
August 26, 2025 at 3:48 AM
That’s my point: If “COVID-AIDS” occurs, most likely there would also be “SARS-AIDS”. And SARS acute infections were two decades ago giving plenty of time for a “SARS-AIDS” to emerge. But has such a thing emerged? As best I know, no. So the probability of “COVID-AIDS” emerging is greatly diminished.
August 6, 2025 at 2:00 PM
I think I missed an important point on this thread: Some people are concerned that after several years COVID will lead to an HIV-like immune collapse.

My point is that SARS1 is quite similar to COVID. Not the same, but quite similar. And an HIV-like immune collapse has not happened with SARS1.
August 6, 2025 at 1:37 PM
There are some who worry that COVID is “Airborne AIDS” with a near-100% occurrence nasty post-acute syndrome. That’s the motive behind my comparison with SARS.
August 5, 2025 at 8:51 PM
For comparison of post-acute SARS risks with post-acute HIV risks aka AIDS, the post-acute sample size for SARS probably is big enough. In the absence of treatment, what is the rate of immune collapse within 15 years post acute HIV infection? Just shy of 100%?
August 5, 2025 at 8:22 PM
As far as I’m aware, most antibodies to SARS-CoV-2 target the Spike, N, and ORF8. And many of those aren’t neutralizing especially outside the Spike RBD and NTD targets. So yeah, there’s not much antibody response against the main protease or other replication complex proteins.
August 5, 2025 at 2:55 PM
I haven’t heard of significant antibody responses to the main protease, and I’ve only heard of significant neutralizing responses to the spike.

However, the main protease is the target of Paxlovid and some other antivirals.
August 4, 2025 at 9:26 PM
Finally, quoting from Strauss and Howe’s older “The Fourth Turning” (p. 318): “Classic virtues that didn’t necessarily pay off in an Unraveling (traits like trust, reliability, patience, perseverance, thrift, and selflessness) will become hard currency in a Crisis.” 6/6
July 29, 2025 at 9:32 PM
As the world is highly interconnected now, and foreign dignitaries may well be implicated in the Epstein Files, this realignment may start in America but spread throughout the world. 5/6
July 29, 2025 at 9:32 PM
I’m in that 89% and 92%. And anyone who wants the Epstein Files released is my ally. If you want the Epstein Files released, you’re my ally whether you’re MAGA, or you’re Never Trumper, or you’re a Democrat, or you’re Progressive/Socialist/Leftist. 4/6
July 29, 2025 at 9:31 PM
A July 16-18, 2025 CBS News YouGov poll found 89% of Americans wanted the Epstein Files released and 92% thought those files likely implicated powerful or wealthy people (Source Q40 and 41 at d3nkl3psvxxpe9.cloudfront.net/documents/cb...) In a badly divided America, this agreement is remarkable. 3/6
d3nkl3psvxxpe9.cloudfront.net
July 29, 2025 at 9:30 PM
Quoting Neil Howe’s “The Fourth Turning Is Here” (p. 190): “In every other case, society’s first regeneracy, after giving birth to two or more dominant groups, eventually weakens. These groups then fragment and reassemble during a second regeneracy.” 2/6
July 29, 2025 at 9:28 PM