yileifu.bsky.social
Yilei Fu
@yileifu.bsky.social
46 followers 51 following 4 posts
Ph.D. Candidate @ Computer Science Department, Rice University
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smahtnetwrk.bsky.social
smahtnetwrk.bsky.social @smahtnetwrk.bsky.social · Jul 3
The SMaHT marker paper is now live in @nature.com 🧬

This landmark study characterizes somatic variation across 19 tissue types from 150 nondiseased donors, laying the groundwork for future discoveries in health, aging, and disease.

Read the full paper: www.nature.com/articles/s41...
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Reposted by Yilei Fu
sedlazeck.bsky.social
Fritz Sedlazeck @sedlazeck.bsky.social · Apr 3
Long reads such as @nanoporetech.com or @pacbio.bsky.social can provide insights into epigenetic. We
@yileifu.bsky.social & @timp0.bsky.social )summarize the latest #Bioinformatics approaches & why this matters! Out now @natrevgenet.bsky.social at:
bit.ly/4cjxUtl
@bcmhouston.bsky.social @jhu.edu
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yileifu.bsky.social
Yilei Fu @yileifu.bsky.social · Mar 29
We summarized state-of-the-art computational methods for DNA methylation analysis using long-read sequencing, covering everything from base calling to sample-level, cell-type-level, and even population-scale analysis. Huge thanks to @sedlazeck.bsky.social and @timp0.bsky.social for this great work!
natrevgenet.nature.com
Nature Reviews Genetics @natrevgenet.nature.com · Mar 28
New online! Computational analysis of DNA methylation from long-read sequencing
Computational analysis of DNA methylation from long-read sequencing
Nature Reviews Genetics, Published online: 28 March 2025; doi:10.1038/s41576-025-00822-5Long-read sequencing technologies can directly profile methylation modifications across the genome. In this Review, Fu et al. overview the long-read computational tools to identify and compare methylation signals, as well as tools that use these methylation signals to analyse cell-type diversity and gain additional genomic insights.
www.nature.com
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Reposted by Yilei Fu
natrevgenet.nature.com
Nature Reviews Genetics @natrevgenet.nature.com · Jan 21
New online! Diversity and consequences of structural variation in the human genome
Diversity and consequences of structural variation in the human genome
Nature Reviews Genetics, Published online: 21 January 2025; doi:10.1038/s41576-024-00808-9Collins and Talkowski provide a broad overview of structural variation in the human genome that covers their mutational properties, the dynamics of population…
go.nature.com
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Reposted by Yilei Fu
sedlazeck.bsky.social
Fritz Sedlazeck @sedlazeck.bsky.social · Apr 29
Had a great lab retreat on Saturday at rice together with @svillapol.bsky.social and @treangen.bsky.social lab. Amazing talks, discussions and overlap of interests. Won't be the last one :)
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yileifu.bsky.social
Yilei Fu @yileifu.bsky.social · Mar 11
www.sciencedirect.com/science/arti... Check out our newest paper about comparing long- and short- read metagenome sequencing and EpicPCR when it comes to ARG detection in wastewater. Great collab with Esther Lou and Lauren Stadler lab @RiceCEE and my former lab Qi Wang, @treangen.bsky.social
Sensitivity and consistency of long- and short-read metagenomics and epicPCR for the detection of antibiotic resistance genes and their bacterial hosts in wastewater
Wastewater surveillance is a powerful tool to assess the risks associated with antibiotic resistance in communities. One challenge is selecting which …
www.sciencedirect.com
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yileifu.bsky.social
Yilei Fu @yileifu.bsky.social · Nov 30
Thank you Daniel!
yileifu.bsky.social
Yilei Fu @yileifu.bsky.social · Nov 28
Great day in my life!! Finally defended my Ph.D.!
I can’t do this without the guidance of my Ph.D. advisor
@treangen.bsky.social and my co-advisor @sedlazeck.bsky.social ! I’ll soon join @sedlazeck.bsky.social ’s group at as an postdoc focusing on cancer genetics and cancer epigenetics.
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