Nobel prize-winning biologist whose discovery, with Francis Crick, of the structure of DNA solved the mystery of genetic inheritance

Lausanne; London

The synapse may hold the key to treating major depressive disorder and dementia

Chiral, photoswitchable dopants composed of triptycene and azobenzene exhibit exceptionally large helical twisting powers that change dramatically upon isomerization when incorporated into the liquid...

The company is training AI models with data generated by its own technology

The infection mechanism of Colletotrichum capsici on chilli plants was revealed and it was found that the silver nanoparticles can be used to control anthracnose disease in the chilli plants.

Photochemistry and total synthesis are deeply rooted in the history of organic chemistry, each developing independently while also intersecting frequently. Indeed, mild reaction conditions, versatility of transformations, and complementary selectivities to thermal methods make photochemistry an especially powerful tool for the synthesis of complex target molecules. In this Review, we highlight recent examples of total syntheses (from 2020 to 2025) featuring photochemical reactions as pivotal steps. Although the application of photochemistry in total synthesis has been consistently reviewed throughout the past decades, we feel that the wider emergence of photocatalytic methods, together with the continued importance of certain direct irradiation approaches, warrants its own discussion. We hope that our analytical approach and strategic insights will help us to identify cases where photochemical reactions could prove useful, thereby further encouraging their use in total syntheses.

Model links reaction energy to activation energy

Start-up may have a catalyst that finally makes the process work

High-entropy alloy (HEA) nanoparticles, self-supporting HEA aerogels and HEA coatings with up to 11 metal elements and uniform elemental distributions have been synthesized at subzero temperatures usi...

Lapse in federal food aid strains some researchers and undergraduates