the ultimate carcinogens are epoxides formed in metabolism, that escape, to alkylate DNA before being rearranged. Any structural feature that stabilizes the epoxides typically results in more carcinogenicity, unless it opens up a different pathway for metabolism. So benzene is weakly (2/n)
November 7, 2025 at 1:37 AM
the ultimate carcinogens are epoxides formed in metabolism, that escape, to alkylate DNA before being rearranged. Any structural feature that stabilizes the epoxides typically results in more carcinogenicity, unless it opens up a different pathway for metabolism. So benzene is weakly (2/n)
So I've read into this quite extensively, after using PAH compounds in ligands (some still unpublished), and not wanting to inadvertently make something dangerous. I can summarize: The carcinogenicity really depends on structure. There's a "bay theory" of carcinogenicity, where essentially (1/n)
November 7, 2025 at 1:36 AM
So I've read into this quite extensively, after using PAH compounds in ligands (some still unpublished), and not wanting to inadvertently make something dangerous. I can summarize: The carcinogenicity really depends on structure. There's a "bay theory" of carcinogenicity, where essentially (1/n)
Carcinogenic effects of long-term exposure from prenatal life to glyphosate and glyphosate-based herbicides in Sprague-Dawley rats - PubMed bit.ly/3JfzP8l
![Text Shot: Conclusions: Glyphosate and GBHs at exposure levels corresponding to the EU ADI and the EU NOAEL caused dose-related increases in incidence of multiple benign and malignant tumors in SD rats of both sexes. Early-life onset and mortality were observed for multiple tumors. These results provide robust evidence supporting IARC's conclusion that there is "sufficient evidence of carcinogenicity [of glyphosate] in experimental animals". Furthermore, our data are consistent with epidemiological evidence on the carcinogenicity of glyphosate and GBHs.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:tewmicyycecxzeogol5xtafs/bafkreigdvdwwze7j5e5cx5vasrsdvb5zcrwqlqrupeea47r7s5t6omarre@jpeg)
November 1, 2025 at 7:57 AM
Carcinogenic effects of long-term exposure from prenatal life to glyphosate and glyphosate-based herbicides in Sprague-Dawley rats - PubMed bit.ly/3JfzP8l
IN ONE HOUR: Hear about current frameworks and the state of the science in understanding and testing chemical carcinogenicity with NAMs and discuss new horizons in the field during a free #SOTWebinar. Learn more and register: toxchange.toxicology.org/events/event...
October 27, 2025 at 2:00 PM
IN ONE HOUR: Hear about current frameworks and the state of the science in understanding and testing chemical carcinogenicity with NAMs and discuss new horizons in the field during a free #SOTWebinar. Learn more and register: toxchange.toxicology.org/events/event...
TOMORROW: Hear about current frameworks and the state of the science in understanding and testing chemical carcinogenicity with NAMs and discuss new horizons in the field during a free #SOTWebinar. Learn more and register: toxchange.toxicology.org/events/event...
October 26, 2025 at 5:38 PM
TOMORROW: Hear about current frameworks and the state of the science in understanding and testing chemical carcinogenicity with NAMs and discuss new horizons in the field during a free #SOTWebinar. Learn more and register: toxchange.toxicology.org/events/event...
Same.
Sausages have varying amounts too, plus they'll have varying amounts of nitrites, which pushes up the carcinogenicity.
I don't eat formed mock meats often as I don't view them as a frequent food. Meat is viewed differently and I did before veganism. The health outcome data is important!
Sausages have varying amounts too, plus they'll have varying amounts of nitrites, which pushes up the carcinogenicity.
I don't eat formed mock meats often as I don't view them as a frequent food. Meat is viewed differently and I did before veganism. The health outcome data is important!
The Salty Truth: Uncovering the Amount of Salt in the Average Sausage - KitchenJournal
Sausages are a staple in many cuisines around the world, and their savory flavor is a major contributor to their popularity. However, have you ever stopped to
kitchenjournal.net
October 22, 2025 at 11:31 AM
Same.
Sausages have varying amounts too, plus they'll have varying amounts of nitrites, which pushes up the carcinogenicity.
I don't eat formed mock meats often as I don't view them as a frequent food. Meat is viewed differently and I did before veganism. The health outcome data is important!
Sausages have varying amounts too, plus they'll have varying amounts of nitrites, which pushes up the carcinogenicity.
I don't eat formed mock meats often as I don't view them as a frequent food. Meat is viewed differently and I did before veganism. The health outcome data is important!
"Rethinking Chemical Carcinogenicity Assessment in the Context of NAMs: Current Frameworks, State of the Science, and New Horizons" is the title of a joint #SOTWebinar taking place October 27. Learn more: toxchange.toxicology.org/events/event...
October 13, 2025 at 7:56 PM
"Rethinking Chemical Carcinogenicity Assessment in the Context of NAMs: Current Frameworks, State of the Science, and New Horizons" is the title of a joint #SOTWebinar taking place October 27. Learn more: toxchange.toxicology.org/events/event...
Quantifying the impact of perceived cancer risk on housing values using widely advertised national reclassifications of chemical carcinogenicity in the US, from Jules H. van Binsbergen, João F. Cocco, Marco Grotteria, and S. Lakshmi Naaraayanan https://www.nber.org/papers/w34305
October 5, 2025 at 5:00 PM
Quantifying the impact of perceived cancer risk on housing values using widely advertised national reclassifications of chemical carcinogenicity in the US, from Jules H. van Binsbergen, João F. Cocco, Marco Grotteria, and S. Lakshmi Naaraayanan https://www.nber.org/papers/w34305
/3
* Chronic health issues are linked to exposure to nano- and microplastics, including respiratory diseases, reproductive issues, neurotoxicity, and carcinogenicity.
* Do not use plastic bottles.
more in Optimisticstorm.com
pubmed.ncbi.nlm.nih.gov/40555020/
* Chronic health issues are linked to exposure to nano- and microplastics, including respiratory diseases, reproductive issues, neurotoxicity, and carcinogenicity.
* Do not use plastic bottles.
more in Optimisticstorm.com
pubmed.ncbi.nlm.nih.gov/40555020/
Commercialising Innovative Technologies - Optimistic Storm
Commercialising Innovative Technologies is an area of work by Dr Hugh Butler for the past 40 years. IT, Renewable Energy, Health.
Optimisticstorm.com
October 1, 2025 at 7:42 AM
/3
* Chronic health issues are linked to exposure to nano- and microplastics, including respiratory diseases, reproductive issues, neurotoxicity, and carcinogenicity.
* Do not use plastic bottles.
more in Optimisticstorm.com
pubmed.ncbi.nlm.nih.gov/40555020/
* Chronic health issues are linked to exposure to nano- and microplastics, including respiratory diseases, reproductive issues, neurotoxicity, and carcinogenicity.
* Do not use plastic bottles.
more in Optimisticstorm.com
pubmed.ncbi.nlm.nih.gov/40555020/
Avobenzone, a common UV filter, has a strong safety profile. Despite concerns, extensive research shows minimal toxicity, low absorption, and no evidence of carcinogenicity, supporting it...
🧵 Thread below
Full analysis: https://helixbrief.com/article/1b5d8d1d-6a6a-45e8-afa4-0b7e807d6620
🧵 Thread below
Full analysis: https://helixbrief.com/article/1b5d8d1d-6a6a-45e8-afa4-0b7e807d6620
September 29, 2025 at 7:35 PM
Avobenzone, a common UV filter, has a strong safety profile. Despite concerns, extensive research shows minimal toxicity, low absorption, and no evidence of carcinogenicity, supporting it...
🧵 Thread below
Full analysis: https://helixbrief.com/article/1b5d8d1d-6a6a-45e8-afa4-0b7e807d6620
🧵 Thread below
Full analysis: https://helixbrief.com/article/1b5d8d1d-6a6a-45e8-afa4-0b7e807d6620
« The authors noted that extant research identified "respiratory diseases, reproductive issues, neurotoxicity, and carcinogenicity" among the chronic conditions and health impacts associated with exposure to microplastics and nanoplastics. »
September 21, 2025 at 5:50 PM
« The authors noted that extant research identified "respiratory diseases, reproductive issues, neurotoxicity, and carcinogenicity" among the chronic conditions and health impacts associated with exposure to microplastics and nanoplastics. »
i put this in the YouTube comments too, but if you ever want to do a follow-up episode, one of the biggest things contributing to cigarette carcinogenicity is the natural radionucleides on the tobacco leaf
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Waking a Sleeping Giant: The Tobacco Industry’s Response to the Polonium-210 Issue
The major tobacco manufacturers discovered that polonium was part of tobacco and tobacco smoke more than 40 years ago and attempted, but failed, to remove this radioactive substance from their product...
pmc.ncbi.nlm.nih.gov
September 14, 2025 at 4:06 AM
i put this in the YouTube comments too, but if you ever want to do a follow-up episode, one of the biggest things contributing to cigarette carcinogenicity is the natural radionucleides on the tobacco leaf
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
When a wildfire destroys much of your city, how do you know if your house is too contaminated with toxins to move back in?
Ask emmarcourt.bsky.social
www.bloomberg.com/news/feature...
Ask emmarcourt.bsky.social
www.bloomberg.com/news/feature...
September 11, 2025 at 4:18 PM
When a wildfire destroys much of your city, how do you know if your house is too contaminated with toxins to move back in?
Ask emmarcourt.bsky.social
www.bloomberg.com/news/feature...
Ask emmarcourt.bsky.social
www.bloomberg.com/news/feature...
Hear about current frameworks and the state of the science in understanding and testing chemical carcinogenicity with NAMs and discuss new horizons in the field during a free #SOTWebinar on October 27. Learn more and register: toxchange.toxicology.org/events/event...
September 10, 2025 at 3:22 PM
Hear about current frameworks and the state of the science in understanding and testing chemical carcinogenicity with NAMs and discuss new horizons in the field during a free #SOTWebinar on October 27. Learn more and register: toxchange.toxicology.org/events/event...
The findings will provide a comprehensive understanding of PFOA's hepatotoxicity and carcinogenicity, enabling the identification of potential targets for risk assessment and intervention strategies related to environmental exposure.
September 9, 2025 at 4:50 AM
The findings will provide a comprehensive understanding of PFOA's hepatotoxicity and carcinogenicity, enabling the identification of potential targets for risk assessment and intervention strategies related to environmental exposure.
Great documentary about the unethical tactics of Monsanto and the carcinogenicity of glyphosate
youtu.be/CxVXvFOPIyQ?...
youtu.be/CxVXvFOPIyQ?...
Exposing Why Farmers Can't Legally Replant Their Own Seeds
YouTube video by Veritasium
youtu.be
September 7, 2025 at 7:05 PM
Great documentary about the unethical tactics of Monsanto and the carcinogenicity of glyphosate
youtu.be/CxVXvFOPIyQ?...
youtu.be/CxVXvFOPIyQ?...
These are so refreshing compared to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) symbols.
September 6, 2025 at 1:58 PM
These are so refreshing compared to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) symbols.
I've seen the stuff about interactions with chemotherapy, but haven't seen good evidence of carcinogenicity. Happy to learn more if you have a source.
September 4, 2025 at 1:29 PM
I've seen the stuff about interactions with chemotherapy, but haven't seen good evidence of carcinogenicity. Happy to learn more if you have a source.
A woman with an immune defect developed #betaHPV–integrated skin cancer. Stem-cell transplant restored T-cell function and cleared all HPV diseases — revealing the direct #carcinogenicity of β-HPV under immune deficiency. ➡️ bit.ly/3HwYRis
Paper highlights have been summarized ⬇️
#IPVSPaperoftheWeek
Paper highlights have been summarized ⬇️
#IPVSPaperoftheWeek
August 29, 2025 at 5:15 AM
A woman with an immune defect developed #betaHPV–integrated skin cancer. Stem-cell transplant restored T-cell function and cleared all HPV diseases — revealing the direct #carcinogenicity of β-HPV under immune deficiency. ➡️ bit.ly/3HwYRis
Paper highlights have been summarized ⬇️
#IPVSPaperoftheWeek
Paper highlights have been summarized ⬇️
#IPVSPaperoftheWeek
.
Micro-Projects
#c3_MP0017 PFAS Exploration
.
Curation Projects
#c3_CP012 Pollution
#C3_Cp061 PFAS Pollution
#C3_Cp060 IndustReality+DeGeneration
.
Notes
THE LANCET - Oncology:
Carcinogenicity of perfluorooctanoic acid and perfluorooctanesulfonic acid
www.thelancet.com/journals/lan...
Micro-Projects
#c3_MP0017 PFAS Exploration
.
Curation Projects
#c3_CP012 Pollution
#C3_Cp061 PFAS Pollution
#C3_Cp060 IndustReality+DeGeneration
.
Notes
THE LANCET - Oncology:
Carcinogenicity of perfluorooctanoic acid and perfluorooctanesulfonic acid
www.thelancet.com/journals/lan...
Carcinogenicity of perfluorooctanoic acid and perfluorooctanesulfonic acid
In November, 2023, a Working Group of 30 scientists from 11 countries met at the International
Agency for Research on Cancer (IARC) in Lyon, France, to finalise their evaluation
of the carcinogenicity...
www.thelancet.com
August 26, 2025 at 12:16 AM
.
Micro-Projects
#c3_MP0017 PFAS Exploration
.
Curation Projects
#c3_CP012 Pollution
#C3_Cp061 PFAS Pollution
#C3_Cp060 IndustReality+DeGeneration
.
Notes
THE LANCET - Oncology:
Carcinogenicity of perfluorooctanoic acid and perfluorooctanesulfonic acid
www.thelancet.com/journals/lan...
Micro-Projects
#c3_MP0017 PFAS Exploration
.
Curation Projects
#c3_CP012 Pollution
#C3_Cp061 PFAS Pollution
#C3_Cp060 IndustReality+DeGeneration
.
Notes
THE LANCET - Oncology:
Carcinogenicity of perfluorooctanoic acid and perfluorooctanesulfonic acid
www.thelancet.com/journals/lan...
A two year carcinogenicity study in rats reports increased benign and malignant tumor rates after continuous exposure to glyphosate or glyphosate-based herbicides
The exposure levels studied in this research are considered low or acceptable, including 0.5, 5, and 50 mg/kg of body weight per day
The exposure levels studied in this research are considered low or acceptable, including 0.5, 5, and 50 mg/kg of body weight per day
Most widely used herbicide in the world is now linked to leukemia and tumors
A two-year study in rats links glyphosate to tumors, even at acceptable doses; prenatal and adult exposure concerns regulatory authorities.
www.earth.com
August 24, 2025 at 7:48 PM
A two year carcinogenicity study in rats reports increased benign and malignant tumor rates after continuous exposure to glyphosate or glyphosate-based herbicides
The exposure levels studied in this research are considered low or acceptable, including 0.5, 5, and 50 mg/kg of body weight per day
The exposure levels studied in this research are considered low or acceptable, including 0.5, 5, and 50 mg/kg of body weight per day
STUPID HUMANS STRIKE AGAIN!
"A 2yr carcinogenicity study in rats reports increased benign & malignant tumor rates after continuous exposure to glyphosate or glyphosate-based herbicides.
The exposure levels studied in this research are considered low or acceptable"
www.earth.com/news/most-wi... .
"A 2yr carcinogenicity study in rats reports increased benign & malignant tumor rates after continuous exposure to glyphosate or glyphosate-based herbicides.
The exposure levels studied in this research are considered low or acceptable"
www.earth.com/news/most-wi... .
Most widely used herbicide in the world is now linked to leukemia and tumors
A two-year study in rats links glyphosate to tumors, even at acceptable doses; prenatal and adult exposure concerns regulatory authorities.
www.earth.com
August 23, 2025 at 4:22 PM
STUPID HUMANS STRIKE AGAIN!
"A 2yr carcinogenicity study in rats reports increased benign & malignant tumor rates after continuous exposure to glyphosate or glyphosate-based herbicides.
The exposure levels studied in this research are considered low or acceptable"
www.earth.com/news/most-wi... .
"A 2yr carcinogenicity study in rats reports increased benign & malignant tumor rates after continuous exposure to glyphosate or glyphosate-based herbicides.
The exposure levels studied in this research are considered low or acceptable"
www.earth.com/news/most-wi... .
The results indicate that the majority of participants had a good understanding of the facilities required for cytotoxic reconstitution and were highly concerned about the potential risks, such as carcinogenicity and reproductive toxicity.
August 12, 2025 at 4:48 AM
The results indicate that the majority of participants had a good understanding of the facilities required for cytotoxic reconstitution and were highly concerned about the potential risks, such as carcinogenicity and reproductive toxicity.
No doubt you've heard activists claiming that the Global Glyphosate Study provides definitive proof that glyphosate is a carcinogen.
Of course the NGOs would say that.
Bob Tarone, who wrote the guidance on animal carcinogenicity studies, found flaws and bias.
www.thefirebreak.org/p/the-global...
Of course the NGOs would say that.
Bob Tarone, who wrote the guidance on animal carcinogenicity studies, found flaws and bias.
www.thefirebreak.org/p/the-global...
August 8, 2025 at 4:27 PM
No doubt you've heard activists claiming that the Global Glyphosate Study provides definitive proof that glyphosate is a carcinogen.
Of course the NGOs would say that.
Bob Tarone, who wrote the guidance on animal carcinogenicity studies, found flaws and bias.
www.thefirebreak.org/p/the-global...
Of course the NGOs would say that.
Bob Tarone, who wrote the guidance on animal carcinogenicity studies, found flaws and bias.
www.thefirebreak.org/p/the-global...
The Ramazzini Institute published its #GlobalGlyphosateStudy with heavy promotion from NGOs and tort lawyers.
Guest writer Robert Tarone, who coauthored the IARC guidance on animal carcinogenicity studies, criticizes the GGS as seriously faulty and biased.
www.thefirebreak.org/p/the-global...
Guest writer Robert Tarone, who coauthored the IARC guidance on animal carcinogenicity studies, criticizes the GGS as seriously faulty and biased.
www.thefirebreak.org/p/the-global...
The Global Glyphosate Study: Another Ramazzini Travesty of Science
Serious Flaws in the GGS Sprague Dawley Rat Carcinogenicity Findings
www.thefirebreak.org
August 6, 2025 at 11:08 AM
The Ramazzini Institute published its #GlobalGlyphosateStudy with heavy promotion from NGOs and tort lawyers.
Guest writer Robert Tarone, who coauthored the IARC guidance on animal carcinogenicity studies, criticizes the GGS as seriously faulty and biased.
www.thefirebreak.org/p/the-global...
Guest writer Robert Tarone, who coauthored the IARC guidance on animal carcinogenicity studies, criticizes the GGS as seriously faulty and biased.
www.thefirebreak.org/p/the-global...