A new review of multicancer early detection tests (MCED). Without any controlled studies in people without symptoms (and at increased risk), they are "not ready for popular use." @annalsofim.bsky.social
www.acpjournals.org/doi/10.7326/...
www.acpjournals.org/doi/epdf/10....
www.acpjournals.org/doi/10.7326/...
www.acpjournals.org/doi/epdf/10....
September 15, 2025 at 10:46 PM
A new review of multicancer early detection tests (MCED). Without any controlled studies in people without symptoms (and at increased risk), they are "not ready for popular use." @annalsofim.bsky.social
www.acpjournals.org/doi/10.7326/...
www.acpjournals.org/doi/epdf/10....
www.acpjournals.org/doi/10.7326/...
www.acpjournals.org/doi/epdf/10....
A paper using RRID:SCR_021137 was just published in Clinical Cancer Research see "Noninvasive Multicancer Detection Using DNA Hypomethylation of LINE-1 Retrotransposons". We appreciate the author's support of reproducibility. #OpenScience #methodsmatter
doi.org
February 26, 2025 at 8:02 AM
A paper using RRID:SCR_021137 was just published in Clinical Cancer Research see "Noninvasive Multicancer Detection Using DNA Hypomethylation of LINE-1 Retrotransposons". We appreciate the author's support of reproducibility. #OpenScience #methodsmatter
Time for my first post on bluesky.
Our DIAMOND paper on multicancer detection from blood using LINE-1 hypomethylation is now available in its peer-reviewed version at clinical cancer research @CCR_AACR aacrjournals.org/clincancerre...
Wishing everyone blue skies in 2025 ;)
Our DIAMOND paper on multicancer detection from blood using LINE-1 hypomethylation is now available in its peer-reviewed version at clinical cancer research @CCR_AACR aacrjournals.org/clincancerre...
Wishing everyone blue skies in 2025 ;)
Noninvasive Multicancer Detection Using DNA Hypomethylation of LINE-1 Retrotransposons
AbstractPurpose:. The detection of ctDNA, which allows noninvasive tumor molecular profiling and disease follow-up, promises optimal and individualized management of patients with cancer. However, det...
aacrjournals.org
January 29, 2025 at 5:42 PM
Time for my first post on bluesky.
Our DIAMOND paper on multicancer detection from blood using LINE-1 hypomethylation is now available in its peer-reviewed version at clinical cancer research @CCR_AACR aacrjournals.org/clincancerre...
Wishing everyone blue skies in 2025 ;)
Our DIAMOND paper on multicancer detection from blood using LINE-1 hypomethylation is now available in its peer-reviewed version at clinical cancer research @CCR_AACR aacrjournals.org/clincancerre...
Wishing everyone blue skies in 2025 ;)
For a second week in a row, our top trending #AJVR article was "High-sensitivity multicancer detection of stage 1 cancer in dogs": doi.org/10.2460/ajvr...
Our top trending AJVR article last week was "High-sensitivity multicancer detection of stage 1 cancer in dogs": doi.org/10.2460/ajvr...
A blood-based test may address the challenges in detecting stage 1 canine cancers, creating opportunities for improved treatment outcomes. 🐕 Open access article: jav.ma/multicancer
June 30, 2025 at 2:44 PM
For a second week in a row, our top trending #AJVR article was "High-sensitivity multicancer detection of stage 1 cancer in dogs": doi.org/10.2460/ajvr...
Clinical Validation of a Noninvasive Multi-Omics Method for Multicancer Early Detection in Retrospective and Prospective Cohorts.
Free #OpenAccess text: www.jmdjournal.org/article/S152...
Free #OpenAccess text: www.jmdjournal.org/article/S152...
Clinical Validation of a Noninvasive Multi-Omics Method for Multicancer Early Detection in Retrospective and Prospective Cohorts
Recent studies highlight the promise of blood-based multicancer early detection (MCED)
tests for identifying asymptomatic patients with cancer. However, most focus on a
single cancer hallmark, thus li...
www.jmdjournal.org
July 21, 2025 at 3:33 PM
Clinical Validation of a Noninvasive Multi-Omics Method for Multicancer Early Detection in Retrospective and Prospective Cohorts.
Free #OpenAccess text: www.jmdjournal.org/article/S152...
Free #OpenAccess text: www.jmdjournal.org/article/S152...
In depth analysis re #multicancer detection tests - subscription required. https://cancerletter.com/clinical/20241025_1/
November 27, 2024 at 9:31 PM
In depth analysis re #multicancer detection tests - subscription required. https://cancerletter.com/clinical/20241025_1/
Blood-based multicancer detection (MCD) tests have emerged as a potentially transformative approach for cancer screening. The findings of a new systematic review assessing benefits, accuracy, and harms of MCD tests can inform focus areas for additional research. Read here: bit.ly/4n2Sz9x
September 16, 2025 at 3:47 PM
Blood-based multicancer detection (MCD) tests have emerged as a potentially transformative approach for cancer screening. The findings of a new systematic review assessing benefits, accuracy, and harms of MCD tests can inform focus areas for additional research. Read here: bit.ly/4n2Sz9x
💉 US scientists say there's a lack of evidence around the accuracy, benefits and potential harms of commercially available blood tests that claim to be able to detect many different types of cancer (multicancer detection [MCD] tests)
buff.ly/H6jhENM
#science #research #cancer #bloodtest
buff.ly/H6jhENM
#science #research #cancer #bloodtest
September 16, 2025 at 7:07 AM
💉 US scientists say there's a lack of evidence around the accuracy, benefits and potential harms of commercially available blood tests that claim to be able to detect many different types of cancer (multicancer detection [MCD] tests)
buff.ly/H6jhENM
#science #research #cancer #bloodtest
buff.ly/H6jhENM
#science #research #cancer #bloodtest
Bill Alert!
US House Bill HR 842 - Nancy Gardner Sewell Medicare Multi-Cancer Early Detection Screening Coverage Act
Full Details: https://hozzl.com/p/bill/119-hr-bill-number-842-nancy-gardner-sewell-medicare-multicancer-early-detection-screening-coverage-act?utm_source=bluesky&utm_medium=autop...
US House Bill HR 842 - Nancy Gardner Sewell Medicare Multi-Cancer Early Detection Screening Coverage Act
Full Details: https://hozzl.com/p/bill/119-hr-bill-number-842-nancy-gardner-sewell-medicare-multicancer-early-detection-screening-coverage-act?utm_source=bluesky&utm_medium=autop...
April 25, 2025 at 3:17 AM
Bill Alert!
US House Bill HR 842 - Nancy Gardner Sewell Medicare Multi-Cancer Early Detection Screening Coverage Act
Full Details: https://hozzl.com/p/bill/119-hr-bill-number-842-nancy-gardner-sewell-medicare-multicancer-early-detection-screening-coverage-act?utm_source=bluesky&utm_medium=autop...
US House Bill HR 842 - Nancy Gardner Sewell Medicare Multi-Cancer Early Detection Screening Coverage Act
Full Details: https://hozzl.com/p/bill/119-hr-bill-number-842-nancy-gardner-sewell-medicare-multicancer-early-detection-screening-coverage-act?utm_source=bluesky&utm_medium=autop...
Excited to be presenting on #insurance coverage at @theNASEM Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests: A Workshop https://www.nationalacademies.org/event/42236_10-2024_opportunities-and-challenges-for-the-development-and-adoption-of-multicancer...
November 27, 2024 at 9:31 PM
Excited to be presenting on #insurance coverage at @theNASEM Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests: A Workshop https://www.nationalacademies.org/event/42236_10-2024_opportunities-and-challenges-for-the-development-and-adoption-of-multicancer...
GWAS and 3D chromatin mapping identifies multicancer risk genes associated with hormone-dependent cancers https://www.medrxiv.org/content/10.1101/2024.07.14.24310389v1
GWAS and 3D chromatin mapping identifies multicancer risk genes associated with hormone-dependent cancers https://www.medrxiv.org/content/10.1101/2024.07.14.24310389v1
Hormone-dependent cancers (HDCs) share several risk factors, suggesting a common aetiology. Using da
www.medrxiv.org
July 16, 2024 at 5:40 AM
GWAS and 3D chromatin mapping identifies multicancer risk genes associated with hormone-dependent cancers https://www.medrxiv.org/content/10.1101/2024.07.14.24310389v1
What are your takeaways from the session “Multicancer Early Detection—Are There Cures Without Costs?”
Let us know your thoughts in the comments #ASCO25
Let us know your thoughts in the comments #ASCO25
June 2, 2025 at 3:35 PM
What are your takeaways from the session “Multicancer Early Detection—Are There Cures Without Costs?”
Let us know your thoughts in the comments #ASCO25
Let us know your thoughts in the comments #ASCO25
Efficient Cancer Biomarker Screening and Multicancer Detection Enabled by a Multidimensional Serum Proteomic Strategy pubs.acs.org/doi/abs...
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#proteomics #prot-paper
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#proteomics #prot-paper
November 24, 2024 at 9:00 AM
Efficient Cancer Biomarker Screening and Multicancer Detection Enabled by a Multidimensional Serum Proteomic Strategy pubs.acs.org/doi/abs...
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#proteomics #prot-paper
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#proteomics #prot-paper
That full body MRI advertised to you? Tests pushed by influencers result in stress, unnecessary diagnoses and treatments.
Also problematic: multicancer early detection (MCED) test, antimullerian hormone (AMH), gut microbiome, testosterone.
jamanetwork.com/journals/jam...
Also problematic: multicancer early detection (MCED) test, antimullerian hormone (AMH), gut microbiome, testosterone.
jamanetwork.com/journals/jam...
Social Media Posts About Medical Tests With Potential for Overdiagnosis
This cross-sectional study examines the tone and content of social media posts that discuss popular medical tests with potential for overdiagnosis or overuse.
jamanetwork.com
March 6, 2025 at 4:09 PM
That full body MRI advertised to you? Tests pushed by influencers result in stress, unnecessary diagnoses and treatments.
Also problematic: multicancer early detection (MCED) test, antimullerian hormone (AMH), gut microbiome, testosterone.
jamanetwork.com/journals/jam...
Also problematic: multicancer early detection (MCED) test, antimullerian hormone (AMH), gut microbiome, testosterone.
jamanetwork.com/journals/jam...
Excited to be speaking at @theNASEM Workshop on #insurance & #MCD: Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests https://www.nationalacademies.org/event/42236_10-2024_opportunities-and-challenges-for-the-development-and-adoption-of-multicancer-de...
January 9, 2025 at 8:26 PM
Excited to be speaking at @theNASEM Workshop on #insurance & #MCD: Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests https://www.nationalacademies.org/event/42236_10-2024_opportunities-and-challenges-for-the-development-and-adoption-of-multicancer-de...
Researchers found genetic signs of cancer in the blood up to three years before diagnosis.
The study, funded in part by NIH, highlights the promise of multicancer early detection tests to give patients more time for treatment and better outcomes. #ResearchSavesLives
hub.jhu.edu/2025/06/04/n...
The study, funded in part by NIH, highlights the promise of multicancer early detection tests to give patients more time for treatment and better outcomes. #ResearchSavesLives
hub.jhu.edu/2025/06/04/n...
Cancers can be detected in bloodstream three years prior to diagnosis
Detection of cancer before a clinical diagnosis could give patients and caregivers more time for intervention and may lead to better outcomes because tumors are more likely to be curable
hub.jhu.edu
June 11, 2025 at 2:43 AM
Researchers found genetic signs of cancer in the blood up to three years before diagnosis.
The study, funded in part by NIH, highlights the promise of multicancer early detection tests to give patients more time for treatment and better outcomes. #ResearchSavesLives
hub.jhu.edu/2025/06/04/n...
The study, funded in part by NIH, highlights the promise of multicancer early detection tests to give patients more time for treatment and better outcomes. #ResearchSavesLives
hub.jhu.edu/2025/06/04/n...
Psychosocial impacts associated with GRAIL, a multicancer early detection test
New data on patient-reported outcomes at 12 months from the PATHFINDER study
www.thelancet.com/journals/lan...
#GastroSky #MedSky #OncSky @oncoalert.bsky.social
New data on patient-reported outcomes at 12 months from the PATHFINDER study
www.thelancet.com/journals/lan...
#GastroSky #MedSky #OncSky @oncoalert.bsky.social
January 14, 2025 at 2:49 PM
Psychosocial impacts associated with GRAIL, a multicancer early detection test
New data on patient-reported outcomes at 12 months from the PATHFINDER study
www.thelancet.com/journals/lan...
#GastroSky #MedSky #OncSky @oncoalert.bsky.social
New data on patient-reported outcomes at 12 months from the PATHFINDER study
www.thelancet.com/journals/lan...
#GastroSky #MedSky #OncSky @oncoalert.bsky.social
Multicancer analyses of short tandem repeat variations reveal shared gene regulatory mechanisms https://www.biorxiv.org/content/10.1101/2025.01.06.629343v1
January 7, 2025 at 11:47 PM
Multicancer analyses of short tandem repeat variations reveal shared gene regulatory mechanisms https://www.biorxiv.org/content/10.1101/2025.01.06.629343v1
I CELEBRATED MY HEALTHY 70 MULTICANCER GENETIC PANEL REPORT BY EATING PEPPER JACK CHEESE STICKS, MY FAVE SNACK:)
May 10, 2025 at 10:50 AM
I CELEBRATED MY HEALTHY 70 MULTICANCER GENETIC PANEL REPORT BY EATING PEPPER JACK CHEESE STICKS, MY FAVE SNACK:)
Multicancer Detection Tests Not Ready for Prime Time, Review Suggests
(MedPage Today) -- The jury is still out on the merits of multicancer detection (MCD) tests in asymptomatic adults, according to results from a systematic review. Across 20 studies reporting on the accuracy of 19 tests, test…
(MedPage Today) -- The jury is still out on the merits of multicancer detection (MCD) tests in asymptomatic adults, according to results from a systematic review. Across 20 studies reporting on the accuracy of 19 tests, test…
Multicancer Detection Tests Not Ready for Prime Time, Review Suggests
(MedPage Today) -- The jury is still out on the merits of multicancer detection (MCD) tests in asymptomatic adults, according to results from a systematic review. Across 20 studies reporting on the accuracy of 19 tests, test sensitivity ranged... Source link
n24usa.com
September 15, 2025 at 10:03 PM
Multicancer Detection Tests Not Ready for Prime Time, Review Suggests
(MedPage Today) -- The jury is still out on the merits of multicancer detection (MCD) tests in asymptomatic adults, according to results from a systematic review. Across 20 studies reporting on the accuracy of 19 tests, test…
(MedPage Today) -- The jury is still out on the merits of multicancer detection (MCD) tests in asymptomatic adults, according to results from a systematic review. Across 20 studies reporting on the accuracy of 19 tests, test…
High-sensitivity multicancer detection of stage 1 cancer in dogs. avmajournals.avma.org/view/journal...
avmajournals.avma.org
June 24, 2025 at 3:26 AM
High-sensitivity multicancer detection of stage 1 cancer in dogs. avmajournals.avma.org/view/journal...
From the National Human Genome Research Institute:
Evaluating Stacked Methylation Markers for Blood-Based Multicancer Detection
www.preprints.org/manuscript/2...
Evaluating Stacked Methylation Markers for Blood-Based Multicancer Detection
www.preprints.org/manuscript/2...
www.preprints.org
January 29, 2025 at 2:08 PM
From the National Human Genome Research Institute:
Evaluating Stacked Methylation Markers for Blood-Based Multicancer Detection
www.preprints.org/manuscript/2...
Evaluating Stacked Methylation Markers for Blood-Based Multicancer Detection
www.preprints.org/manuscript/2...
#PrimaryCareUpdate Episode 184: new UTI antibiotic, drugs for fibromyalgia, trial of a multicancer detection test for screening, and the best time for HTN meds #EBM #InfoPOEMs #EssentialEvidencePlus #STFM #NAPCRG #PrimaryCare #FamilyMedicine
creators.spotify.com/pod/show/pri...
creators.spotify.com/pod/show/pri...
Episode 184: new UTI antibiotic, fibromyalgia tx, trial of an MCED, and the best time for HTN meds by Primary Care Update
Join Mark, Kate, Henry and Gary as they discuss 4 new POEMs: a new and very hard to pronounce antibiotic for uncomplicated UTI, the best drugs for relieving pain in adults with fibromyalgia, a clinica...
creators.spotify.com
July 2, 2025 at 6:39 PM
#PrimaryCareUpdate Episode 184: new UTI antibiotic, drugs for fibromyalgia, trial of a multicancer detection test for screening, and the best time for HTN meds #EBM #InfoPOEMs #EssentialEvidencePlus #STFM #NAPCRG #PrimaryCare #FamilyMedicine
creators.spotify.com/pod/show/pri...
creators.spotify.com/pod/show/pri...
#multicancer - ранното откриване на рака е от ключово значение за оп-добра прогноза- www.linkedin.com/posts/lifesc... - @nmgenomix.bsky.social - една от компаниите, в които съм инвестирал, предлага такъв тест в България, базиран на протеомен анализ и изкуствен интелект
Transforming cancer screening: the potential of multi-cancer early… | Dimitar Georgiev
Много хубава статия с отворен достъп за т.нар. #multicancer early #detection тестове- https://lnkd.in/diqV67De -потенциалът е голям, но все още има за доизкусуряване. Нашата компания NM Genomix зае...
www.linkedin.com
April 13, 2025 at 5:12 AM
#multicancer - ранното откриване на рака е от ключово значение за оп-добра прогноза- www.linkedin.com/posts/lifesc... - @nmgenomix.bsky.social - една от компаниите, в които съм инвестирал, предлага такъв тест в България, базиран на протеомен анализ и изкуствен интелект
MUST READ @dallasnews story on how #multicancer early detection saved a life. @RepScottPeters @RepJuanVargas @RepSaraJacobs @repdarrellissa @RepMikeLevin let’s pass #MCEDAct NOW and ensure more people can have access to these technologies....
March 22, 2025 at 1:34 AM
MUST READ @dallasnews story on how #multicancer early detection saved a life. @RepScottPeters @RepJuanVargas @RepSaraJacobs @repdarrellissa @RepMikeLevin let’s pass #MCEDAct NOW and ensure more people can have access to these technologies....