Brilliant work by Xinpei Jiang, the first PhD student of the #CañadasLab! #proud
Super excited that our paper is out in Cell Reports @cp-cellreports.bsky.social! We show that spliceosome inhibitors trigger ZBP1-driven necroptosis in small cell lung cancer #SCLC enhancing immunotherapy responses! #CañadasLab! #FoxChaseCancer www.sciencedirect.com/science/arti...
Spliceosome inhibition induces Z-RNA and ZBP1-driven cell death in small cell lung cancer
Spliceosome inhibitors emerged as promising anticancer agents. Recent studies have demonstrated that spliceosome-targeted therapies (STTs) trigger ant…
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