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Reposted by Alexandre Djiane

University of Cambridge @cam.ac.uk · 5d

It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social

Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r

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Reposted by Alexandre Djiane

EDRC2025 @edrc2025.bsky.social · 14d

We have had a great final morning at #EDRC2025 with three fantastic keynote lectures by Maria Gambetta, Tor Erik Rusten and Silke Sachse

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Reposted by Alexandre Djiane

EDRC2025 @edrc2025.bsky.social · 17d

3, 2, 1 and we are on!!! #EDRC2025 is starting! Welcome to our more than 740 participants from more than 40 countries! Thank you to all our sponsors!

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Reposted by Alexandre Djiane

Development @dev-journal.bsky.social · 20d

Read the article ‘Mushroom bodies tiny regulates Sidekick localization to tricellular adherens junctions’ here: doi.org/10.1242/dev....

Mushroom bodies tiny regulates Sidekick localization to tricellular adherens junctions

Highlighted Article: Localization of the cell-adhesion molecule Sidekick to tricellular adherens junctions requires specific extracellular domains and its intracellular binding partner, the PAK4 kinas...

doi.org

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Alexandre Djiane @adjiane.bsky.social · 27d

Congratulations!
So Sunday notifications are good. Nice!
My experience is that Friday notifications just before WE or holidays are bad, really bad...

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Reposted by Alexandre Djiane

Hadi Boukhatmi @muscleflylab.bsky.social · Aug 30

Our new preprint is out !
We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles.
Check it out and please share
@igdrennes.bsky.social

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Alexandre Djiane @adjiane.bsky.social · Aug 29

BTW, same goes for grant reviews...

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Alexandre Djiane @adjiane.bsky.social · Aug 29

Shame on the reviewers to be that lazy and disrespectful. I had similar suspicion with another publisher. Some claims of the reviewers were completely wrong. Discussed with editors about the issues without actually calling them AI generated. Is there a way to prove it was AI generated?

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Alexandre Djiane @adjiane.bsky.social · Aug 14

But it is a fraction of the price, and extremely robust (ours is a shared equipment for the institute).

Alexandre Djiane @adjiane.bsky.social · Aug 14

My point is it is great to count objects and have a pretty picture with less background and blur (even though confocal remains way better), but I would be extremely cautious for intensity quantification.

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Alexandre Djiane @adjiane.bsky.social · Aug 14

We use it daily on Drosophila tissues. It gives pretty images, but it remains epifluorescence (more bleed through) and one must remain extremely careful with the "levels" seen on the screen.

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Alexandre Djiane @adjiane.bsky.social · Aug 11

Bravo!

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Alexandre Djiane @adjiane.bsky.social · Jul 17

After manuscript reviews full of inaccuracies which appear AI generated, and final grant rejection (despite excellent reviews), I will let the disappointment and anger pass, and will not review your manuscript tonight. I apologise for the potential delay, but you might thank me later.

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Alexandre Djiane @adjiane.bsky.social · Jul 12

Great ressource!

Reposted by Alexandre Djiane

jakbosch.bsky.social @jakbosch.bsky.social · Jul 11

I’m thrilled to share a @biorxivpreprint for my postdoc work in the @PerrimonLab🎉. Together with our collaborators, we built a tissue-specific atlas of circulating secreted proteins in Drosophila 🧬🪰🧪🗺️.
Thread below🧵
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www.biorxiv.org/content/10.1...

Multi-omic mapping of Drosophila protein secretomes reveals tissue-specific origins and inter-organ trafficking

Secreted proteins regulate many aspects of animal biology and are attractive targets for biomarkers and therapeutics. However, comprehensively identifying the "secretome", along with their tissues of ...

www.biorxiv.org

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Alexandre Djiane @adjiane.bsky.social · Jul 5

That is a tough one to beat... But sometimes it is better these obviously bitter reviews that can be dismissed with the editors (once you have let the anger pass), than those who want to kill your paper by asking an endless list of unfeasible experiments (to which editors rarely, hum never, say no)

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Alexandre Djiane @adjiane.bsky.social · Jun 23

Congratulations!

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Reposted by Alexandre Djiane

Bardin Lab @bardinlab.bsky.social · Jun 5

Very happy to share our latest lab publication!
The hard work of @bboumard.bsky.social, Gwenn Le Meur and collaborators!
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila: Developmental Cell
authors.elsevier.com/a/1lDFi_Yv6z...

Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila

Boumard et al. demonstrate gap-junction-dependent tissue-scale nucleotide sharing, which impacts cellular sensitivity to perturbation of nucleotide homeostasis and replication stress. Drosophila wing ...

www.cell.com

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Reposted by Alexandre Djiane

fly paper broadcast @fly-broadcast.bsky.social · Jun 4

Serotonergic neurons regulate the Drosophila vascular niche to control immune stress hematopoiesis
#Drosophila

Serotonergic neurons regulate the Drosophila vascular niche to control immune stress hematopoiesis #Drosophila

PubMed link

pubmed.ncbi.nlm.nih.gov

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Reposted by Alexandre Djiane

Lucas Waltzer @lucaswaltzer.bsky.social · Jun 3

#drosophila @flybase.bsky.social request emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!

www.philanthropy.cam.ac.uk/give-to-camb...

Drosophila Genetic Database

The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

www.philanthropy.cam.ac.uk

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Reposted by Alexandre Djiane

Dmitri Petrov @petrovadmitri.bsky.social · Jun 3

Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...

Drosophila Genetic Database

The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

www.philanthropy.cam.ac.uk

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Alexandre Djiane @adjiane.bsky.social · May 24

At the end of a seminar part of an interview process, after 15 minutes of question and a good exchange waiting to be last to talk: "What you propose is exactly what not to do..."

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Reposted by Alexandre Djiane

Levayer Lab @levayerr.bsky.social · May 21

Many cells during development are exposed to caspase activation and yet survive. Why some die and not others ? We found out that the memory of previous caspase activation bias significantly later death comitment and bias death distribution and single cell decision
www.biorxiv.org/content/10.1...

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Reposted by Alexandre Djiane

Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · May 15

📣 Junior PI Opportunity
Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰
450k€ package | Drosophila, RNA, immunity
IBMC + Labex NetRNA network
📅 Apply by June 30, 2025
🔗 ibmc.cnrs.fr/en/laboratoi...
#RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert

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Alexandre Djiane @adjiane.bsky.social · May 13

PS: would be very interested to have your feed back on the specificity of these TRE / mRE-DsRed in muscles. Thanx

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