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Andrew Hardaway @andrewhardaway.bsky.social · 11h

These are terrific ideas.

Aaron Rupar @atrupar.com · 14h

Thune: "If the Democrats had won the majority, they probably would've tried to nuke the filibuster. And then you'd have four new senators from Puerto Rico and DC, you'd have a packed Supreme Court, you'd have abortion on demand ... "

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Andrew Hardaway @andrewhardaway.bsky.social · 1d

Awesome news! Congrats!

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Reposted by Andrew Hardaway

Ann Kennedy @antihebbiann.bsky.social · 1d

Finally out: our recent work with Nick Betley is a view into how the brain reshapes its behavior in the face of competing survival needs- and also a potential angle on treatment targets for enduring pain.

A brief rundown...

www.nature.com/articles/s41...

A parabrachial hub for need-state control of enduring pain - Nature

Activity in a set of parabranchial neurons in the mouse brain is increased during chronic pain, predicts coping behaviour, and can be modulated by circuits activated by survival threats.

www.nature.com

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Reposted by Andrew Hardaway

Patrick Piantadosi @ppiantad.bsky.social · 1d

for anyone interested in the amygdala and risky decision-making, check out our new preprint: biorxiv.org/content/10.1...

amygdala neurons track reward-seeking actions, and punishment risk dramatically alters this function. lots of other (BLA-accumbens!) data included.

Risk reshapes amygdala representation of choice

Modifying behavior in response to changing environmental conditions is a crucial adaptive function. This capacity is exemplified when animals curtail pursuit of a valued outcome that risks being punis...

biorxiv.org

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Reposted by Andrew Hardaway

Loren DeJonge Schulman @lorenraeds.bsky.social · 3d

Former OMB associate director on personnel here: This is blatantly false and inexplicably undermines Congress's authority. Congress made extremely clear in 2019 that furloughed feds are to be paid, full stop, period. There is no question, except why the Speaker would make such a statement.

Aaron Rupar @atrupar.com · 3d

Johnson: "It's true that in previous shutdowns, many or most furloughed employees have been paid for the time they were furloughed, but there is new legal analysis - I don't know the details, I just saw a headline - but there are some legal analysts saying that might not be appropriate or necessary"

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Andrew Hardaway @andrewhardaway.bsky.social · 2d

People who know me know I rarely shill for much, but my experience at UAB as a family member of a patient was amazing. Huge thanks to Neurosurgery and Drs. Kristen Riley, Brad Woodworth, and Harrison Walker (Neurology).

Andrew Hardaway @andrewhardaway.bsky.social · 2d

Context here. In August, my mom developed a CSF leak and subsequent pneumocephalus. Her initial ENT and neurosurgeon were unable to identify the leak and were suggesting a full and bilateral craniotomy to go in and fix it. I moved her to UAB and she got the care she needed. She is recovering well.

Andrew Hardaway @andrewhardaway.bsky.social · 2d

Flip side, you can also have n = 1 patient like my mom being treated by a highly trained neurosurgeon who was suggesting a highly risky and invasive surgery that is no longer the standard of care and it was only by me (not an MD) challenging the surgeon that she got the procedure she needed.

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Andrew Hardaway @andrewhardaway.bsky.social · 2d

Completely agree. And I hate that we are in an age where armchair podcasters seem to have more influence than those with actual expertise. I think my mom's was a rare case, but it's one where me being a salty questioner of authority paid off and the authority had it wrong.

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Andrew Hardaway @andrewhardaway.bsky.social · 2d

Context here. In August, my mom developed a CSF leak and subsequent pneumocephalus. Her initial ENT and neurosurgeon were unable to identify the leak and were suggesting a full and bilateral craniotomy to go in and fix it. I moved her to UAB and she got the care she needed. She is recovering well.

Andrew Hardaway @andrewhardaway.bsky.social · 2d

Flip side, you can also have n = 1 patient like my mom being treated by a highly trained neurosurgeon who was suggesting a highly risky and invasive surgery that is no longer the standard of care and it was only by me (not an MD) challenging the surgeon that she got the procedure she needed.

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Andrew Hardaway @andrewhardaway.bsky.social · 2d

I wanna be clear that I am not trying to dump on all MDs and that I value data and expertise.

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Andrew Hardaway @andrewhardaway.bsky.social · 2d

Clearly there is a role for expertise. I am not suggesting otherwise and I also don't like it when individuals overextrapolate from a limited sample of experience. What was helpful in my case was being connected with multiple physicians and being a neuroscientist - privilege.

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Andrew Hardaway @andrewhardaway.bsky.social · 2d

Mostly I agree with you, but I experienced this last month. The doc was not up to date on the standard of care to deal with her issue. Docs are people too and sometimes they just don't know. The good ones acknowledge when they don't know.

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Andrew Hardaway @andrewhardaway.bsky.social · 2d

Flip side, you can also have n = 1 patient like my mom being treated by a highly trained neurosurgeon who was suggesting a highly risky and invasive surgery that is no longer the standard of care and it was only by me (not an MD) challenging the surgeon that she got the procedure she needed.

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Andrew Hardaway @andrewhardaway.bsky.social · 3d

a picture of darth vader with the words most impressive written below him

Alt: a picture of darth vader with the words most impressive written below him

media.tenor.com

Reposted by Andrew Hardaway

Dr Kat Day (she/her) @chronicleflask.katday.com · 4d

Daughter of Robin Williams, Zelda Williams 💔

zeldawilliams
20m
From Create Mode
••
Please, just stop sending me AI videos of Dad. Stop believing I wanna see it or that I'll understand, I don't and I won't. If you're just trying to troll me, I've seen way worse, i'll restrict and move on. But please, if you've got any decency, just stop doing this to him and to me, to everyone even, full stop. It's dumb, it's a waste of time and energy, and believe me, it's NOT what he'd want.
To watch the legacies of real people be condensed down to 'this vaguely looks and sounds like them so that's enough,
, just so
other people can churn out horrible TikTok slop puppeteering them is maddening. You're not making art, you're making disgusting, over-processed hotdogs out of the lives of human beings, out of the history of art and music, and then shoving them down someone else's throat hoping they'll give you a little thumbs up and like it.
Gross.

And for the love of EVERYTHING, stop calling it 'the future. Al is just badly recycling and regurgitating the past to be reconsumed. You are taking in the Human Centipede of content, and from the very very end of the line, all while the folks at the front laugh and laugh, consume and consume.

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Andrew Hardaway @andrewhardaway.bsky.social · 5d

You can do worse, BUT Vrabel teams will not be particularly innovative or novel. He is a Parcells throwback without a Parcells track record. For sure Belichick is an influence too. The rep doesn't match the record.