Andrew Hardaway
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andrewhardaway.bsky.social
Andrew Hardaway
@andrewhardaway.bsky.social
Nerd, Husband, Dad, and Neuroscientist in Alabama. Flawed. Occasionally opines on football, cats, and beer. He/him
"Forth Eorlingas!"
https://hardawaylab.org/
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Today we celebrate the 34th anniversary of one of the greatest films of all time: "Teenage Mutant Ninja Turtles: The Movie"

A thread.
Reposted by Andrew Hardaway
So excited to see our latest paper out today in @natcomms.nature.com! Studies led by the amazing @margestelzner.bsky.social www.nature.com/articles/s41.... VTA GABA neurons have a unique role in economic decision making - they integrate reward seeking motivation and the current cost of seeking
Ventral tegmental area GABA neurons integrate positive and negative valence - Nature Communications
The role of ventral tegmental area GABA neurons in behavior is unclear. Here, authors show that VTA GABA but not dopamine neurons integrate positive and negative valence to encode motivational conflic...
www.nature.com
November 24, 2025 at 4:18 PM
Reposted by Andrew Hardaway
My favorite from an @hhmi.org scientist: “the great thing about optogenetics is it keeps the riff raff out of the field.”
Heard an established successful neuroscientist dismissing junior scientists as "people at the bottom" 🤦‍♀️

You folks with lots of research funds & power: young scientists more than ever need our respect and support even if you don't agree with their ideas and approaches
#sfn2025
November 23, 2025 at 3:27 PM
Reposted by Andrew Hardaway
Vaccines save lives.

And no, they do not cause autism.
November 22, 2025 at 5:00 PM
Reposted by Andrew Hardaway
BATTLE AWAITS. DO YOUR STRETCHES.
November 22, 2025 at 4:40 AM
Reposted by Andrew Hardaway
And now we cut to a live shot of Stephen Miller.
November 21, 2025 at 9:09 PM
Show me you want to look like you you're implementing new policy without actually implementing new policy.
November 21, 2025 at 9:13 PM
Reposted by Andrew Hardaway
And all of this connects directly to the discussion here.

Right now, NIH institute directors are civil servants and experienced, top-expert scientists. That is the way NIH has run for decades.

It looks like Trump and Vought are planning to politicize those positions.
A bad thing is unfolding at NIH this week: It looks like the Trump administration is trying to replace key civil servant scientific leaders, the Institute Directors, with political hires. These directors control the NIH budget, tens of billions.

A bit of a video explainer here: 1/ 🧪
November 20, 2025 at 11:14 PM
Reposted by Andrew Hardaway
An entire argument dismantled in two words.
CNN: What if there are more names connected to the Democratic Party that come out in the files?

CHRIS MURPHY: So what?
November 20, 2025 at 1:11 PM
Reposted by Andrew Hardaway
We knew this regulation was going into effect, but we didn't yet know whether and how NIH might seek to use it.

Yesterday, we found out. NIH will indeed add specific language to new grant terms and, in doing so, it'll preserve the option to use this new power.

grants.nih.gov/grants/guide...

2/
November 19, 2025 at 1:35 PM
Reposted by Andrew Hardaway
And the full segment that aired last night!
The lab is at the end but the whole segment is interesting. Never stand next to me at a party, I will at some point rant about gras…

abcnews.go.com/Health/globa...
November 20, 2025 at 1:39 PM
Reposted by Andrew Hardaway
Luke nails it, this just tells us the bubble isn't in the process of popping not that it isn't a bubble.
“Nvidia Gives Strong Forecast, Countering Fears of AI Bubble”

I very much disagree with this framing. People buying lots of Nvidia GPUs tells us nothing about the eventual ROI on those GPUs.

In fact, a bubble effectively <requires> “too many” of these to be bought.
November 19, 2025 at 10:08 PM
Reposted by Andrew Hardaway
Alright, I guess I will start the Grants - 2026 subfolder.
night of champions wwe GIF
night of champions wwe GIF
giphy.com
November 13, 2025 at 5:24 PM
When I use the word bespoke in a grant.
a man with curly hair wearing a grey sweater and a yellow sweatshirt
Alt: a man with curly hair wearing a grey sweater and a yellow sweatshirt
media.tenor.com
November 18, 2025 at 11:19 PM
Reposted by Andrew Hardaway
The lab was on Good Morning America! Absolutely surreal. Everyone did so great on the filming day. I work with the best people ever.
November 18, 2025 at 1:29 PM
Reposted by Andrew Hardaway
I am so tired of “full responsibility” that involves no action and “shame” that kicks in only upon public disclosure.
SUMMERS: “.. I am deeply ashamed of my actions and recognize the pain they have caused. I take full responsibility for my misguided decision to continue communicating with Mr. Epstein.”

@politico.com
www.politico.com/news/2025/11...
November 18, 2025 at 1:35 AM
Life as a #Titans fan.
Hello Darkness My Old Friend GIF
ALT: Hello Darkness My Old Friend GIF
media.tenor.com
November 17, 2025 at 12:03 AM
This is probably the most shilling I have ever done for UAB but campus was fall flexing today.
November 15, 2025 at 1:03 AM
Reposted by Andrew Hardaway
Hearing a rumor that NIH/HHS may now plan to retaliate against other Bethesda Declaration signers.

I am one, but it’s not about me: we have been speaking out because of the ongoing damage to US medical research, cancer and Alzheimer’s research.

As @jenna-m-norton.bsky.social put well: 1/
November 14, 2025 at 4:17 PM
Seems bad. The backlog of high quality but yet unfunded grants cometh.
Just got an email from my SRO for the study section that was missed in October. Good news is that they are trying to reschedule ASAP (Dec/Jan). The bad news is that CSR is mandating that only the the top third (not half) of applications will get discussed for the next 2 rounds.
November 13, 2025 at 11:52 PM
Reposted by Andrew Hardaway
Trump’s HHS put me on “non-disciplinary” admin leave today. This was retaliation for speaking up. Moves like this are designed to silence us. Let’s not let.

www.tiktok.com/t/ZP8Dteoop/
I guess I am hitting a nerve, because they just put me on admin leave.
TikTok video by Jenna
www.tiktok.com
November 13, 2025 at 11:18 PM
Alright, I guess I will start the Grants - 2026 subfolder.
night of champions wwe GIF
night of champions wwe GIF
giphy.com
November 13, 2025 at 5:24 PM
Reposted by Andrew Hardaway
every few years it's revealed that the NYT was sitting on information about some horrific thing that public knowledge of would have changed the country's course and for some reason a ton of people still give them money. you can play those games on other sites
November 12, 2025 at 10:41 PM
Reposted by Andrew Hardaway
While the government was shut down, 379 NIH study section meetings (containing 24,380 grant applications) were postponed. NIH is committed to getting these reviewed, but please be patient and understanding with staff, as this is a complex and heavy lift.
November 13, 2025 at 1:25 PM
Reposted by Andrew Hardaway
The Gowrishankar lab will be opening its doors @neuro_MUSC on Dec 1, 2025! We will be hiring at all levels. I will also be at @SfNtweets presenting my lab's vision on Wednesday, Nov 19, 8AM-12PM at poster board GG7. If you're interested, please reach out!

www.raajgowrishankarlab.org
Gowrishankar Lab
www.raajgowrishankarlab.org
November 12, 2025 at 10:23 PM