ALT: a cartoon character named spongebob is smiling and holding a shovel in his hand

Here they perform a systematic dissection of OCT4 and reveal how intrinsically disordered regions can be used to serve specific functions during reprogramming and embryonic development. This can be exploited to engineer more efficient and specific reprogramming factors.

Here, the authors investigate gene dosage compensation in mouse pluripotent stem cells to better understand the process of X-chromosome upregulation. They report that mammalian cells can sense when segments of one of the two X chromosomes are genetically deleted in cis and compensate gene expression by upregulation in trans.

Signez la pétition maintenant !

Our ‘Featured resource’ series aims to shine a light on the resources that support our research – the unsung heroes of the science world. In this post, we learn about the data and functionalities avai...

Job #AJO30607, WDR-00055221 Assistant Professor, Molecular Biology & Genetics, Cornell University, Ithaca, New York, US