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Epilepsia Journal @epilepsiajournal.bsky.social · 1d

Long-term memory trajectories after epilepsy surgery for TLE/HS show a tendency toward delayed decline, even in seizure-free patients.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #epilepsysurgery #hippocampalsclerosis #memory #temporallobeepilepsy

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Epilepsia Journal @epilepsiajournal.bsky.social · 1d

These results reflect that abnormalities gathered from T1w MRI is useful in delineation of response groups to VNS, and, specifically, that hippocampal damage could be considered when offering VNS to individuals with DRE.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #biomarker #MRI

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Epilepsia Journal @epilepsiajournal.bsky.social · 2d

PEH had a higher burden of psychiatric symptomatology than housed people with epilepsy. Once psychiatric symptomatology was controlled for, there was no difference in quality of life.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #homelessness #mentalhealth

Epilepsia Journal @epilepsiajournal.bsky.social · 2d

Proteomic and phosphoproteomic analyses reveal dysregulated pathways linked to axonal development and synaptic function.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #BRSK1 #lossoffunction #neurodevelopmentaldisorders

Epilepsia Journal @epilepsiajournal.bsky.social · 3d

To advance procedures to select optimal treatment regimens for patients with SCN8A-related epilepsy, we construct an ML algorithm to recommend ASMs based on caregiver assessments.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #machinelearning #pediatricepilepsy #rarediseases #SCN8A

Epilepsia Journal @epilepsiajournal.bsky.social · 4d

Stereotactic radiofrequency thermocoagulation achieved 60% seizure freedom at 12 months using fewer trajectories than previously reported approaches.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #gelasticseizures #hypothalamichamartoma #refractoryepilepsy #surgicaloutcome

Epilepsia Journal @epilepsiajournal.bsky.social · 4d

New in Epilepsia – October 4, 2025
mailchi.mp/ilae/new-art...

Subscribe - eepurl.com/iLSrNc

#epilepsy #epilepsia #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch

Epilepsia Journal @epilepsiajournal.bsky.social · 4d

γ-Aminobutyric acid B receptor (GABABR)-IgG (immunoglobulin G) autoimmune encephalitis often presents as encephalopathy with seizures in the context of underlying small cell lung carcinoma.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #antiGABABreceptor #autoimmuneencephalitis

Epilepsia Journal @epilepsiajournal.bsky.social · 8d

New Special Issue in Epilepsia: AI, Wearables & Digital Health in Epilepsy⁠
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🔗 onlinelibrary.wiley.com/toc/15281167...
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#Epilepsia #EpilepsyResearch #DigitalHealth #AI #Wearables #SeizureDetection #PatientCare #epilepsy #ILAE

Epilepsia Journal @epilepsiajournal.bsky.social · 8d

In univariate analyses, decreased cortical and subcortical metabolism on FDG-PET was a stronger discriminator of dysplastic cortex than surface-based MRI features.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #artificialintelligence #epilepsysurgery #multimodalneuroimaging #AI

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Epilepsia Journal @epilepsiajournal.bsky.social · 9d

Atenolol reduced heart rate and QTc interval, without affecting seizure load in both mouse models of SUDEP.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #atenolol #cardiacarrhythmia #KCNH2 #longQTsyndrome #SUDEP

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Epilepsia Journal @epilepsiajournal.bsky.social · 9d

A holistic, biopsychosocial approach benefits all seizure patients and reflects modern models of epilepsy care.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #epilepticseizures #functionaldissociativeseizures

Epilepsia Journal @epilepsiajournal.bsky.social · 9d

A significant discrepancy is noted in the availability of cannabinoids for the treatment of epilepsy across different geographic settings.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #cannabidiol #cannabinoids #CBD #plantbasedtherapy

Epilepsia Journal @epilepsiajournal.bsky.social · 9d

Letter to the Editor
Open Access

The epileptic heart: Let's not forget to look at the atria!
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #heart #atria #atrialfibrillation #myocardialstrain

The epileptic heart: Let's not forget to look at the atria!

Click on the article title to read more.

doi.org

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Epilepsia Journal @epilepsiajournal.bsky.social · 11d

PWEs and CGs generally support AI-CLDs for SUDEP prevention but emphasize the need for accuracy, reliability, and user control over interventions.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #artificialintelligence #automatedintervention #closedloopsystem #medicaldevice #SUDEP

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Epilepsia Journal @epilepsiajournal.bsky.social · 11d

Volume electron microscopy revealed ultrastructural synaptic and organelle changes in the cortex of a patient with FCD.
doi.org/10.1111/epi....

#epilepsy #epilepsia #ILAE #cortex #electronmicroscopy #hyperexcitability #mitochondria #synapse

Epilepsia Journal @epilepsiajournal.bsky.social · 11d

Interictal low-entropy activity marks epileptogenic zones even without visible spikes or seizures in intracranial electroencephalography (iEEG).
doi.org/10.1111/epi....

#epilepsy #epilepsia #ILAE #entropy #epilepsysurgery #interictaldata #intracranialEEG #outcomeprediction

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Epilepsia Journal @epilepsiajournal.bsky.social · 11d

New in Epilepsia – September 27, 2025
mailchi.mp/ilae/new-art...

Subscribe - eepurl.com/iLSrNc

#epilepsy #epilepsia #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch

Epilepsia Journal @epilepsiajournal.bsky.social · 17d

KCC2 mitigates ictal-like events and their propagation in supragranular layers of neocortical acute brain slices from the seizure propagation zone of TLE patients.
doi.org/10.1111/epi....

#epilepsy #ILAE #Epilepsia #chloridehomeostasis #KCC2 #microelectrodeArray #seizurepropagation

Potassium–chloride cotransporter 2 activity dampens induced ictal‐like activity in neocortical slices containing the seizure propagation zone of temporal lobe epilepsy patients

The K⁺/Cl− cotransporter (KCC2) limits induced ictal-like events and their spread in the supragranular layer of human neocortical slices from the seizure-propagation zone of temporal lobe epilepsy pa...

doi.org

Epilepsia Journal @epilepsiajournal.bsky.social · 17d

Our findings identify augmented ventilatory chemosensitivity and impaired autoresuscitation as critical pathophysiological features of SUDEP.
doi.org/10.1111/epi....

#epilepsy #ILAE #Epilepsia #anoxia #autoresuscitation #chemosensing #respiration #SUDEP

Epilepsia Journal @epilepsiajournal.bsky.social · 19d

Witness recall was experimentally tested 2 and 7 weeks after seeing a seizure, mirroring typical “first seizure” clinic wait times.
doi.org/10.1111/epi....

#epilepsy #ILAE #Epilepsia #accuratediagnosis #firstseizures #recall #waitingtimes #witnesses

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Epilepsia Journal @epilepsiajournal.bsky.social · 19d

New in Epilepsia – September 20, 2025
mailchi.mp/ilae/new-art...

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#epilepsy #epilepsia #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch

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Epilepsia Journal @epilepsiajournal.bsky.social · 22d

The resulting lesion network causing HKS was aligned with the hypometabolic patterns observed in HKS via positron emission tomography–computed tomography.
doi.org/10.1111/epi....

#epilepsy #ILAE #Epilepsia #DBS #functionalconnectivity #MRI #hyperkineticseizures #lesionnetworkmapping

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Epilepsia Journal @epilepsiajournal.bsky.social · 22d

Task-induced high-frequency activity (HFA) is a marker of cortical processing and a promising functional mapping approach for SEEG.
doi.org/10.1111/epi....

#epilepsy #ILAE #Epilepsia #directcorticalstimulation #epilepsysurgery #functionalmapping #highfrequencyactivity #presurgicalevaluation #SEEG

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Epilepsia Journal @epilepsiajournal.bsky.social · 22d

Annual standardized incidence of SE decreased from 18.0 in 2012 to 15.6 per 100 000 in 2019, reflecting an average annual decrease of 1.9%.
doi.org/10.1111/epi....

#epilepsy #ILAE #Epilepsia #epidemiology #incidence #intensivecareunit #statusepilepticus

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