Author | Lightnews

Fluorochem Ltd @fluorochemltd.bsky.social · 29d

We’re proud to highlight the pioneering research and manufacturing organisations we collaborate with, all working at the forefront of chemistry.

On our Insights page, you’ll learn how their products integrate seamlessly into your research🧪
#ScienceSky #Collaboration #ChemSky #LifeSciences

Collaborations Posts | Fluorochem

fluorochem.co.uk

Fluorochem Ltd @fluorochemltd.bsky.social · Oct 2

VHL ligands engage the VHL E3 ligase, a highly validated recruiter in PROTAC design, offering robust degradation profiles. Their structural diversity supports fine-tuning of ternary complex stability and pharmacological properties.

fluorochem.co.uk/product-cate...

🧪 #TargetedProteinDegradation

Fluorochem Ltd @fluorochemltd.bsky.social · Oct 1

Targeted Protein Degradation

Fluorochem is here to support you as you build PROTACs or other heterobifunctional molecules with an excellent range of target-binding ligands, linkers and E3 ubiquitin ligase ligands.

🧪 #ChemicalBiology #LifeSciences #TPD

fluorochem.co.uk/product-cate...

Fluorochem Ltd @fluorochemltd.bsky.social · Sep 25

Cereblon (CRBN) ligands the most extensively used ligase recruiters in targeted protein degradation. The CRL4 CRBN E3 ligase complex is recruited to tag proteins for ubiquitination & degradation. 🧪
#TargetedMedicine #MedicinalChemistry #ProteinDegradation #PharmaResearch #TranslationalResearch #TPD

Fluorochem Ltd @fluorochemltd.bsky.social · Sep 24

Cool cement is helping to keep surfaces cooler. It’s both strong and durable, meaning it can be incorporated into conventional concrete help cities moderate extreme summer temperatures.
#ClimateChange #SustainableConstruction #MaterialsScience #Chemistry 🧪

Scalable metasurface-enhanced supercool cement

Reengineered cement enables scalable radiative cooling for energy-efficient, low-carbon construction.

www.science.org

Fluorochem Ltd @fluorochemltd.bsky.social · Sep 23

Tertrazines are ideal for pre-targeted imaging, drug delivery, and bioorthogonal chemistry. browse our range of click chemistry reagents and much much more on our site!

#Chemistry #ClickChemistry #Imaging #MolecularBiology #MedChem
fluorochem.co.uk/product-cate...
🧪

Fluorochem Ltd @fluorochemltd.bsky.social · Sep 16

There's till time to talk to our rep in Cambridge and find out how Fluorochem can support your ADC and PROTAC synthesis, library development or custom projects!🧪

#CamMedChem25 #ADC #PROTAC #Pharma #ChemSky #BioSky #AcademicSky

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Fluorochem Ltd @fluorochemltd.bsky.social · Sep 15

Another medicinal chemistry symposium this week! Drop by to hear the latest developments at Fluorochem and new ranges in chemical building blocks, biological reagents and complex medicinal agents like ADCs OR heterobifunctional protein degraders!

#CamMedChem25
#ADCs
#ChemSky
#AcademicSky
🧪

Fluorochem Ltd @fluorochemltd.bsky.social · Sep 11

Click chemistry is ideal for fast, selective and modular reactions that simplify complex molecule assembly. In biological systems, copper free reagents are ideal - find them on our site!🧪

fluorochem.co.uk/product-cate...
#ChemSky #BioSky #Biochem #ClickChem #ClickReactions #MolecularBio #MedChem

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Fluorochem Ltd @fluorochemltd.bsky.social · Sep 9

How did click reactions become common practise in synthesis?
🧪

#ClickChem #Chemistry #Biochemistry #ChemSky #clickreactions #Syntheticchem

Fluorochem Ltd @fluorochemltd.bsky.social · Sep 5

Find everything for chemical synthesis, delivered fast, with uncompromising quality 🚚

Click chemistry simplifies complex molecule assembly with fast, selective and modular reactions. Find click reagents & more on our site!🧪
fluorochem.co.uk/product-cate...
#ChemSky #Biochem #Synthesis #Clickchem

Fluorochem Ltd @fluorochemltd.bsky.social · Sep 2

Come and speak to us about all things #peptides #smallmolecules and #medicinalchemistry at the EFMC-ASMC x International Symposium on advances in synthetic and medicinal chemistry.

#medchem #ASMC #EFMCASMC2025 #EFMC

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Fluorochem Ltd @fluorochemltd.bsky.social · Aug 28

Click chemistry has become a go-to strategy for fast, selective and modular reactions that simplify complex molecule assembly. 🧩

Find everything you need to assemble your molecules with Fluorochem’s high quality click reagents!🧪

#ChemSky #ClickChem #Synthesis

fluorochem.co.uk/product-cate...

Fluorochem Ltd @fluorochemltd.bsky.social · Aug 27

Kinases contribute to regulation of cellular signalling and drive many diseases when dysregulated. Small molecule kinase inhibitors allow precise control over these enzymes, enabling pathway dissection, biomarker discovery and therapeutic targeting.🧪
#Kinase #MedChem
fluorochem.co.uk/product-cate...

Fluorochem Ltd @fluorochemltd.bsky.social · Aug 21

Ion channels control the flow of ions across membranes, governing everything from nerve impulses to cardiac rhythms. With small molecule activators and inhibitors, researchers can modulate channel activity with precision. 🧪
#ChemSky #BioSky #MedChem #IonChannel
fluorochem.co.uk/product-cate...

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Fluorochem Ltd @fluorochemltd.bsky.social · Aug 14

Proteases are involved in processes like immunity, cancer progression, and viral replication. Small molecule protease inhibitors help control these enzymes with high specificity, useful in both research and therapeutic applications. 🧪
fluorochem.co.uk/product-cate...
#SMI #protease #ChemSky #cancer

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Fluorochem Ltd @fluorochemltd.bsky.social · Aug 12

Lunar soil is revealing unexpected potential. A team led by Lu Wang has developed a solar-powered photothermal reactor that simultaneously extracts water from regolith and converts exhaled CO₂ into oxygen, hydrogen, and carbon monoxide, with ilmenite as a catalyst. 🧪
#Chemsky #AstroSky #Sciencenews

Simple device can produce water, oxygen and fuel from lunar soil

Using samples collected by the Chinese Chang’e 5 mission, researchers have discovered a new way to release water from lunar regolith and process the carbon dioxide breathed out by astronauts

www.newscientist.com

Fluorochem Ltd @fluorochemltd.bsky.social · Aug 7

GPCRs are highly druggable yet complex. Fluorochem’s small molecules, including agonists & antagonists, help tune signalling processes, study ligand-receptor interactions & explore disease pathways. Perfect tools for #Biochem #DrugDiscovery #MedChem #Protein #Signalling research!

Selection of structures and product details of GPCR modulators available in the Fluorochem catalogue.

Fluorochem Ltd @fluorochemltd.bsky.social · Aug 5

PFAS (“forever chemicals”) are everywhere — water, soil, even our blood. A new study finds they can build up in gut bacteria without harming them. In mice, these PFAS-loaded microbes were later excreted, opening the door to probiotic-based ways to remove PFAS.

#PFAS #PublicHealth #Microbiome

Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances - Nature Microbiology

Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances (PFAS), commonly known as forever chemicals, in intracellular aggregates. Colonization of gnotobiotic mice with bioaccumulating bac...

www.nature.com

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Fluorochem Ltd @fluorochemltd.bsky.social · Jul 31

Phase Transfer Catalysts 🧪

Transporting reaction components between phases, our phase-transfer catalysts efficiently accelerate synthetic and industrial processes while improving solvent economy.

#ChemSky #LabLife #OrgChem #OrganicChemistry #SustainableChemistry

fluorochem.co.uk/product-cate...

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Fluorochem Ltd @fluorochemltd.bsky.social · Jul 29

Researchers have achieved stable devices with 25.5% energy efficiency when combining self-assembling molecules (EPA and MEPA) with Nickel oxide PSCs. Continuous improvement will make solar energy an economically viable answer to energy demand.🧪
#SolarEnergy #GreenChem #Renewable #Sustainability

Bottom‐Up Regulation of Perovskite Growth and Energetics via Oligoether Functionalized Self‐Assembling Molecules for High‐Performance Solar Cells

Oligoether chain was incorporated to construct self-assembling molecules, which can not only enable good coverage and optimized buried interface properties but also assist high-quality and ordered pe...

onlinelibrary.wiley.com

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Fluorochem Ltd @fluorochemltd.bsky.social · Jul 28

Find transition-metal complexes to catalyse molecular remodelling. Fluorochem’s selection covers heavy-hitting stalwarts like Grubbs, precious metal catalysts including palladium and gold and powerful complexes using earth abundant metals.🧪
#ChemSky #Catalysts #Metal #Catalysis #AcademicSky

Fluorochem Ltd @fluorochemltd.bsky.social · Jul 23

Speak to Fluorochem at the 28th International Symposium: Synthesis in Organic Chemistry.
Find out how we can support your #synthesis or #medchem with our extensive range of building blocks, synthesis reagents, #NMR solvents or #photochemistry.
#AcademicSky #Conference #ChemSky #orgchem

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Fluorochem Ltd @fluorochemltd.bsky.social · Jul 17

Organocatalysts

Offering greener methods, while still producing excellent chemical results including highly selective asymmetric catalysis, Fluorochem’s organocatalysts promote countless chemical reactions.

fluorochem.co.uk/product-cate...

#ChemSky #Biosky #catalysts #organocatalyst 🧪

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Fluorochem Ltd @fluorochemltd.bsky.social · Jul 15

Controlled delivery of therapeutic molecules is an ongoing challenge of targeted medicine. This Rotaxane device can release a payload in response to force or an absence of water.
This has been tested with the chemotherapy drug gemcitabine and the biliary antispasmodic drug Hymecromone. 🧪
#ChemSky

onlinelibrary.wiley.com

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