Aaron Logan, MD, PhD, MPhil
@hemedoc.bsky.social
610 followers 110 following 290 posts
Professor, UCSF hematology/BMT. Translational researcher interested in leukemia, MDS, HLH, MRD, post-HCT relapse, GVHD, & immune recon. Photos (Instagram): pyknosis
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Reposted by Aaron Logan, MD, PhD, MPhil
enirenberg.bsky.social
This isn't even a slight exaggeration. He is actively working on destroying the US's entire vaccine infrastructure. The HepB vote will be tomorrow, where they will get rid of the birth dose and recommend it at 30 days, dooming a bunch of infants to chronic infection ft. cirrhosis, cancer, and death.
Reposted by Aaron Logan, MD, PhD, MPhil
gregggonsalves.bsky.social
The chair of the #ACIP is a #COVID-contrarian, Martin Kulldorff, as are others on the committee (i.e., Robert Malone). COVID-contrarians also have hands on the lever of vaccine policy at #FDA (i.e., Vinay Prasad, Tracy Beth Hoeg), at #NIH (i.e., Jay Bhattacharya). 1/
Reposted by Aaron Logan, MD, PhD, MPhil
agawande.bsky.social
9 CDC Directors going back to 1977 speak out. What RFK Jr has done to our nation’s public health system "should alarm every American."

It "is unlike anything we have ever seen at the agency, and unlike anything our country has ever experienced." www.nytimes.com/2025/09/01/o...
Opinion | We Ran the C.D.C.: Kennedy Is Endangering Every American’s Health
www.nytimes.com
hemedoc.bsky.social
Those in MAGA land who voted for this administration don’t realize that these changes will cause hospitals in their small communities to close. Not only will they not have health insurance; they won’t even have ER level care in their communities.
hemedoc.bsky.social
Many of my pts are undoc’d and I hv always been proud of CA for giving them Medi-Cal coverage (CA v of Medicaid). W/o Medicaid $ I don’t know if this can continue .. unless we revolt stop sending so much tax $ to the Fed. But this isn’t just undoc’d — others will also lose access to insurance. Evil.
hemedoc.bsky.social
Lack of auto-renewal is also meant to uninsure more Americans.
hemedoc.bsky.social
Imgs from @johnshopkinssph.bsky.social on IG. In my experience, essentially all people want to work when their health allows. But not everyone can find a job. Making monthly work assessments part of maintaining bare minimum health insurance is a ruse to uninsure more Americans. Disgusting.
hemedoc.bsky.social
Why work when you can just get sick and be paid to take medications in tRump’s delulu version of America?
acyn.bsky.social
Trump: You know, we've cut drug prices by 1200, 1300, 1400, 1,500%. I don't mean 50%. I mean 1400, 1,500%
Reposted by Aaron Logan, MD, PhD, MPhil
scottgottliebmd.bsky.social
From Pink Sheet on continued departures from FDA’s biologics division and challenges backfilling openings. FDA biologics center reported 106 departures from Jan. 1 to June 30. These numbers don’t include the 100-150 who were part of the reduction-in-force

insights.citeline.com/pink-sheet/a...
US FDA’s Biologics Center Departures Grew Before More Than 100 RIFs Exited
The Center for Biologics Evaluation and Research saw departures far outnumber new hires in the second and third quarters of FY 2025, before more than 100 people left July 14 after the reduction-in-for...
insights.citeline.com
Reposted by Aaron Logan, MD, PhD, MPhil
scottgottliebmd.bsky.social
FDA’s cancer review team overseeing breast and gynecological products has lost about 1/3 of its medical review staff and the malignant heme group will lose about 2/3 of its medical review staff—all to voluntary resignations clustered among seasoned reviewers

insights.citeline.com/pink-sheet/a...
hemedoc.bsky.social
Sadly, I’ve seen more public evidence in Latin America and Europe that people care about stopping a holocaust than I’ve seen anywhere in America…
#feedpalestine
diygeochemist.bsky.social
Hello from Latin America. Just because I'm on vacation doesn't mean that I forget what I care about, so I really appreciate this sign...
A stop sign, in Spanish, with some added text, so it now says: "Alto al genocidio" (Stop the genocide)
hemedoc.bsky.social
You are making the situation worse by responding to supporters like this @aoc.bsky.social. Seems very petulant. We are asking for you to oppose even one US tax $ going to the genocidal state. Why did @reprashida.govpeeps.us and @repilhan.bsky.social understand where to position here and you didn’t?
hemedoc.bsky.social
The problem here @aoc is that we expect you to oppose all US taxpayer funding of any genocidal state. I think your calculation on how your vote would be interpreted was wrong. And I think this ends up being a big mistake for you wrt maintaining your base of support nationally. Disappointed in you.
hemedoc.bsky.social
“Working” with ChatGPT is like having an emotionally abusive partner. (Hey OpenAI: the fabrication of references problem has been known for a long time now. Preventing your bot from creating fake references with real PMID numbers that are verifiably wrong with one click should be easy…)
Reposted by Aaron Logan, MD, PhD, MPhil
tedpavlic.bsky.social
Reminder: Nobel-prize winning PCR (1983), used in basically all genetic tech today, was only possible because of extremophile bacterium discovered in 1964 in Yellowstone funded by a small ~$80k NSF grant with no obvious application at the time. #science 🧪
www.richmondscientific.com/how-a-discov...
How a discovery in Yellowstone National Park led to the development of PCR - Richmond Scientific
A discovery in Yellowstone National Park led to the development of PCR, the gold-standard COVID-19 tests used to fight the global pandemic.
www.richmondscientific.com
Reposted by Aaron Logan, MD, PhD, MPhil
kaufm020.bsky.social
Amazing analysis and terrible implications for research in the US. Very impactful research is being eliminated. Worth a look.

The Gutting of America’s Medical Research: Here Is Every Canceled or Delayed N.I.H. Grant www.nytimes.com/interactive/...
Here Are the Nearly 2,500 Medical Research Grants Canceled or Delayed by Trump
Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.
www.nytimes.com
hemedoc.bsky.social
#ASCO25 is going great so far. I love how walkable Chicago is day and night this time of year. Seriously, if anyone knows a place that has the same vibe and weather as late May in Chicago — but year-round — please let me know, because I want to move there!
hemedoc.bsky.social
#ASCO25 Arce-Ruiz: identified ~30K w CH vs 440K wo CH in Biobank DB. Age-related macular degeneration (AMD) appears to be modestly assoc w CH (HR 1.15) but no specific gene mutation indicted as culprit. CH not assoc w vision loss in those with AMD.
hemedoc.bsky.social
#ASCO25 #mpnsm Arce-Ruiz: Macular degeneration in pts w clonal hematopoiesis.
hemedoc.bsky.social
#ASCO25 #mpnsm Andorsky: Asciminib in 2L CML (wo T315I), n=101, treatment ongoing in 91%. 82.5% achieved BCR-ABL <0.1%, 44% MMR at 24wks. Only 3% had AEs leading to discontinuation. Study ongoing.
hemedoc.bsky.social
#ASCO25 #mpnsm Andorsky: Asciminib in 2L treatment of CML (wo T315I). Reason for dc 1L TKI was lack of efficacy in 57% and intolerance 43%.
hemedoc.bsky.social
#ASCO25 #mpnsm Mascarenhas: Imetelstat + Ruxolitinib in Int1/2- and HR-MF. Combo well tolerated with low incidence of tcp. Significant redxn in sx burden and spleen size. Also decreased VAF of driver mutations w combo at Imetelstat RP2D.
hemedoc.bsky.social
#ASCO25 #mpnsm Mascarenhas: Imetelstat + Ruxolitinib in Int1/2- and HR-MF.
hemedoc.bsky.social
#ASCO25 #leusm Goldfinger: Metronomic (weekly) DAC/Ven appears favorable in TP53m MDS/AML vs historical controls (~1/3 of whom recd conventional HMA/Ven). Low rate (12.5%) of febrile neutropenia with metronomic dosing.