Dan Kaufman
@kaufm020.bsky.social
1.8K followers 560 following 55 posts
Professor @UCSD working on stem cells, NK cells, cell therapy and hematology. Golf and baseball also important. kaufmanlab.ucsd.edu
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Reposted by Dan Kaufman
madhupai.bsky.social
Ouch!

"Florida is the first state to take the courageous step toward decluttering itself of excess children, but under the inexpert guidance of Robert F. Kennedy Jr., other states may follow"

@petridishes.bsky.social

www.theatlantic.com/newsletters/...
kaufm020.bsky.social
Amazing analysis and terrible implications for research in the US. Very impactful research is being eliminated. Worth a look.

The Gutting of America’s Medical Research: Here Is Every Canceled or Delayed N.I.H. Grant www.nytimes.com/interactive/...
Here Are the Nearly 2,500 Medical Research Grants Canceled or Delayed by Trump
Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.
www.nytimes.com
kaufm020.bsky.social
Strong analysis.

I am actually a little curious (and terrified) now that the dog has caught the car to see what happens.
kaufm020.bsky.social
Nice to see a rationale approach summarized here. Seems like good strategies.
5 Science-Backed Longevity ‘Hacks’ That Don’t Cost a Fortune www.nytimes.com/2025/04/10/w...
5 Science-Backed Longevity Hacks That Don’t Cost a Fortune
You don’t need a $40,000 gym membership to live a longer, healthier life.
www.nytimes.com
kaufm020.bsky.social
All bleeding stops.
kaufm020.bsky.social
I am looking forward to attending NK2025 in Tasmania (!). Always a great meeting.
See nk2025.au for more info.
#NK2025
kaufm020.bsky.social
Gotta say, for anyone who has cared for patients with Mucor, this looks like pretty good news:
A humanized antibody against mucormycosis targets angioinvasion and augments the host immune response | Science Translational Medicine www.science.org/doi/10.1126/...
A humanized antibody against mucormycosis targets angioinvasion and augments the host immune response
An anti-CotH humanized IgG1 antibody protects against lethal mucormycosis when given as adjunctive therapy to immunocompromised mice.
www.science.org
kaufm020.bsky.social
It starts April 1, so maybe an April Fools joke?
kaufm020.bsky.social
Nice to see our guide on production of iPSC-NK cells out. This method has worked for many groups.
labwaggoner.bsky.social
Detailed step-by-step protocol from cell engineering to differentiation enables the generation of NK cell-optimized iPSC-derived CAR-expressing NK cells
dx.doi.org/10.3791/67438
@kaufm020.bsky.social
kaufm020.bsky.social
Thanks for the update. I do see it works, which is a start. Now I need to figure out if they are funded grants for last year’s submission
kaufm020.bsky.social
So, his supervisor, Dr. Ashe, gets off with no punishment?
kaufm020.bsky.social
Does anyone know if the Congressionally Directed Medical Research Program (CDMRP) is kaput? They fund lots of cancer research. Now all CDMRP-related websites seem to be gone, as below. Any ideas?
Musk and friends likely ended these to fund their tax cuts, but let me know if any other ideas here.
kaufm020.bsky.social
Well, 2% were against this, so, you know, both sides have a point...

Sort of like the minority of climate change deniers, anti-vaxers, etc. 😵‍💫
kaufm020.bsky.social
Very appropriate for the FAA and politicians "investigating" the crash.
kaufm020.bsky.social
He won't pay it. He'll get people to quit, then won't give them the severance. They'll come up with a "reason" later.
kaufm020.bsky.social
This could be a problem, every where, but maybe especially in California, where I am.
Reposted by Dan Kaufman
kaufm020.bsky.social
Russia 2.0. Very techy.
kaufm020.bsky.social
Glad this "genius" is in charge now.
kaufm020.bsky.social
It's great to see this data that shows >80% reduction in childhood cancer deaths. Amazing progress, more to do.
ourworldindata.org
Childhood cancer deaths in the United States have declined six-fold over the last seventy years
This chart presents US cancer death rates in children under five years old, measured in reported annual death rates per 100,000 children. It consists of four graphs:

1. All Malignant Cancers Combined: This graph, shown in black, illustrates a decline in childhood cancer death rates from about 11 per 100,000 in 1950 to around 1.8 in 2021, indicating a six-fold decrease since the 1950s.
   
2. Leukemia: This graph shows a decrease from around 5 per 100,000 in 1950 to less than 1 in 2021, following a similar declining trend throughout the decades.

3. Brain and Nervous System Cancers: This chart shows some fluctuations but overall a decline from nearly 0.8 per 100,000 in 1950 to about 0.4 in 2021.

4. Lymphomas and Multiple Myeloma: This graph shows fluctuations and a decline from around 0.8 in the late 1950s to less than 0.2 by 2021.

The data is sourced from the WHO Mortality Database (2024), with a note indicating that figures may fluctuate year-by-year due to low numbers.
kaufm020.bsky.social
Do they have eggs there?
Reposted by Dan Kaufman
astrojaz.bsky.social
this footage is incredibly haunting.

it’s only been a week since 2025 started.
kaufm020.bsky.social
This does not seem good