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Waggoner Lab @labwaggoner.bsky.social · 1d

ILC3-derived CSF2 tunes homeostasis of tissue macrophages and neutrophils @mucosalimmunology.bsky.social
www.sciencedirect.com/science/arti... @theonlylabever.bsky.social @uoftpress.bsky.social

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Waggoner Lab @labwaggoner.bsky.social · 1d

Promising candidate for next-generation, non-replicating measles vaccines to complement current vaccination strategies: @biorxivpreprint.bsky.social @columbiauniversity.bsky.social @lji.org
Stabilized Full-Length Measles Fusion Protein
www.biorxiv.org/content/10.1...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Brain-infiltrating CD4 T cells drive inflammatory microglia proliferation during cryptococcal meningitis in mice @natcomms.nature.com
www.nature.com/articles/s41...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Perspective @natcomms.nature.com
@harvardmed.bsky.social @precvaccines.bsky.social @bostonchildrens.bsky.social
Incorporating meningeal immunity into vaccine development
www.nature.com/articles/s41...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Targeting IL-6 signaling in parallel with mTOR inhibition, may reduce lung damage in lymphangioleiomyomatosis (LAM) @natcomms.nature.com @uniofnottingham.bsky.social
www.nature.com/articles/s41...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Cxcl9high macrophages recruit circulating Cxcr3+ plasmablasts into kidneys to promote pathogenesis of lupus nephritis mice
www.nature.com/articles/s42...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Extracellular vesicles derived EBV tegument protein BRRF2 suppresses cGAS phase separation to promote anti-viral innate immune evasion @natcomms.nature.com
www.nature.com/articles/s41...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Human gut bacteria produce structurally related monoglycolipids with contrasting immune functions @natmicrobiol.nature.com @harvardmed.bsky.social
www.nature.com/articles/s41...

Human gut bacteria produce structurally related monoglycolipids with contrasting immune functions - Nature Microbiology

The authors identify AgcT as the glycosyltransferase required for synthesis of Bacteroides fragilis-derived α-galactosylceramides (BfaGCs), metabolites known to regulate natural killer T cells, and its structural homologue BgsB that synthesizes α-glycosyl diacylglycerols (aGDGs). They establish a functional link between the production of BfaGCs or aGDGs and the activity and development of natural killer T cells.

www.nature.com

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Waggoner Lab @labwaggoner.bsky.social · 1d

A next-generation anti-CTLA-4 probody (folding the Fab fragment of the antibody in a tumor-associated protease-based manner) mitigates toxicity and enhances anti-tumor immunity in mice @natcomms.nature.com
www.nature.com/articles/s41...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Histone lactylation promotes rheumatoid arthritis progression by increasing NFATc2 expression and the production of anti-lactylated histone autoantibodies @natcomms.nature.com
www.nature.com/articles/s41...

Waggoner Lab @labwaggoner.bsky.social · 1d

Mycobacterium tuberculosis-derived linoleic acid increases regulatory T cell function to promote bacterial survival within macrophages @natmicrobiol.nature.com
www.nature.com/articles/s41...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Review: Viral interferon antagonism shapes host tropism @institutpasteur.bsky.social
journals.plos.org/plospathogen...

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Waggoner Lab @labwaggoner.bsky.social · 1d

“super-adjuvant” nanoparticle system as a modular, customizable platform for next-generation cancer vaccination @cp-cellrepmed.bsky.social @atukoralepu.bsky.social
www.cell.com/cell-reports...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Cohousing or cross-fostering followed by cohousing does not normalize the microbiomes of genetically distinct adult mice @cp-cellreports.bsky.social
www.cell.com/cell-reports...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Developing SEMA4A-directed CAR T cells to overcome low BCMA antigen density in multiple myeloma @cp-cancercell.bsky.social @moffittnews.bsky.social
www.cell.com/cancer-cell/...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Human cytomegalovirus UL78 is a nuclear-localized GPCR necessary for efficient reactivation from latent infection in CD34+ hematopoietic progenitor cells journals.asm.org/doi/10.1128/...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2 @jem.org @weillcornell.bsky.social
rupress.org/jem/article/...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Role for NF-κB in herpes encephalitis pathology in mice genocopying an inborn error of IRF3-IFN immunity @jem.org @aarhusuniint.bsky.social rupress.org/jem/article/...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Faithful modeling of terminal CD8+T cell dysfunction and epigenetic stabilization in vitro @insight.jci.org
@hazemghoneim.bsky.social @ohiostatemed.bsky.social
insight.jci.org/articles/vie...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Intranodal expansion of follicular T helper cells in patients with multiple sclerosis @insight.jci.org
insight.jci.org/articles/vie...

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Waggoner Lab @labwaggoner.bsky.social · 1d

The role of TCF-1+CD8+ exhausted progenitors and TCF-1 in graft-versus-host responses @insight.jci.org
insight.jci.org/articles/vie...

Waggoner Lab @labwaggoner.bsky.social · 1d

Homeostatic conditioning and effector cooperativity between CD8+T and NK cells protect against tumor immune escape @frontiersin.bsky.social
www.frontiersin.org/journals/imm...

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Waggoner Lab @labwaggoner.bsky.social · 1d

Sexually dimorphic defects in cytolytic effector molecules, granule trafficking and release, and increased expression of inhibitory receptors on NK cells in patients hospitalized with COVID-19 (greater in male) @ucalgary.bsky.social
www.frontiersin.org/journals/cel...

Waggoner Lab @labwaggoner.bsky.social · 1d

Tetrameric bispecific KK-LC-1×CD16A-armed cytokine-induced memory-like NK cells enhance antitumor efficacy in gastric cancer
jitc.bmj.com/content/13/1...

Waggoner Lab @labwaggoner.bsky.social · 1d

Bacteria undergo rapid genetic changes that are selected by alterations in the human gut environment @science.org
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...

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