Waggoner Lab
@labwaggoner.bsky.social
Focused on innate immune mechanisms governing pathogenesis of disease and on NK-cell based therapies for disease. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer.
Antibody-conjugated mesenchymal stromal cell drug delivery system for the treatment of autoimmune diseases in mice @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 22, 2026 at 9:48 PM
Antibody-conjugated mesenchymal stromal cell drug delivery system for the treatment of autoimmune diseases in mice @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Innate lymphoid cells activated by the cytokine TL1A link colitis to emergency granulopoiesis and the recruitment of tumor-promoting neutrophils @cp-immunity.bsky.social @weillcornell.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
January 22, 2026 at 9:47 PM
Innate lymphoid cells activated by the cytokine TL1A link colitis to emergency granulopoiesis and the recruitment of tumor-promoting neutrophils @cp-immunity.bsky.social @weillcornell.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Review @cp-cellrepmed.bsky.social
Gut microbiome and obesity care: Bridging dietary, surgical, and pharmacological interventions
www.cell.com/cell-reports...
Gut microbiome and obesity care: Bridging dietary, surgical, and pharmacological interventions
www.cell.com/cell-reports...
January 22, 2026 at 9:43 PM
Review @cp-cellrepmed.bsky.social
Gut microbiome and obesity care: Bridging dietary, surgical, and pharmacological interventions
www.cell.com/cell-reports...
Gut microbiome and obesity care: Bridging dietary, surgical, and pharmacological interventions
www.cell.com/cell-reports...
Review @cp-cellrepmed.bsky.social
Pipe dream to pipeline: Journey of cancer vaccines and the road ahead
www.cell.com/cell-reports...
Pipe dream to pipeline: Journey of cancer vaccines and the road ahead
www.cell.com/cell-reports...
January 22, 2026 at 9:42 PM
Review @cp-cellrepmed.bsky.social
Pipe dream to pipeline: Journey of cancer vaccines and the road ahead
www.cell.com/cell-reports...
Pipe dream to pipeline: Journey of cancer vaccines and the road ahead
www.cell.com/cell-reports...
Dietary methionine mitigates immune-mediated damage by enhancing renal clearance of cytokines @cp-cellmetabolism.bsky.social @salkinstitute.bsky.social
www.cell.com/cell-metabol...
www.cell.com/cell-metabol...
January 22, 2026 at 9:40 PM
Dietary methionine mitigates immune-mediated damage by enhancing renal clearance of cytokines @cp-cellmetabolism.bsky.social @salkinstitute.bsky.social
www.cell.com/cell-metabol...
www.cell.com/cell-metabol...
Breath-based diagnostics? @cp-cellmetabolism.bsky.social @odomjohnlab.bsky.social
Gut bacteria influence the volatile organic compounds found in exhaled in host breath
www.cell.com/cell-metabol...
Gut bacteria influence the volatile organic compounds found in exhaled in host breath
www.cell.com/cell-metabol...
January 22, 2026 at 9:38 PM
Breath-based diagnostics? @cp-cellmetabolism.bsky.social @odomjohnlab.bsky.social
Gut bacteria influence the volatile organic compounds found in exhaled in host breath
www.cell.com/cell-metabol...
Gut bacteria influence the volatile organic compounds found in exhaled in host breath
www.cell.com/cell-metabol...
Cellular senescence in human liver under normal aging and cancer
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
January 22, 2026 at 9:34 PM
Cellular senescence in human liver under normal aging and cancer
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Laser-based collection of bacteria from complex communities or tissue slices for in situ microbial single-cell omics
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
January 22, 2026 at 9:32 PM
Laser-based collection of bacteria from complex communities or tissue slices for in situ microbial single-cell omics
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Spatial transcriptomics reveals altered communities and drivers of aberrant epithelia and pro-fibrotic fibroblasts in interstitial lung diseases
www.cell.com/cell-genomic... @thexavierlab.bsky.social @broadinstitute.org
www.cell.com/cell-genomic... @thexavierlab.bsky.social @broadinstitute.org
January 22, 2026 at 9:30 PM
Spatial transcriptomics reveals altered communities and drivers of aberrant epithelia and pro-fibrotic fibroblasts in interstitial lung diseases
www.cell.com/cell-genomic... @thexavierlab.bsky.social @broadinstitute.org
www.cell.com/cell-genomic... @thexavierlab.bsky.social @broadinstitute.org
Editorial expression of concern @cp-cancercell.bsky.social on
Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth @weldeiry.bsky.social
www.cell.com/cancer-cell/...
Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth @weldeiry.bsky.social
www.cell.com/cancer-cell/...
January 22, 2026 at 9:28 PM
Editorial expression of concern @cp-cancercell.bsky.social on
Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth @weldeiry.bsky.social
www.cell.com/cancer-cell/...
Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth @weldeiry.bsky.social
www.cell.com/cancer-cell/...
ADAR1 deficiency in NK cells is accompanied by CD38 decline (reduced mRNA stability) resulting in increased cell mobility, proliferation, and tumor killing capacity, validating ADAR1 as a target for enhancing NK immunotherapy
advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com/doi/10.1002/...
January 22, 2026 at 9:26 PM
ADAR1 deficiency in NK cells is accompanied by CD38 decline (reduced mRNA stability) resulting in increased cell mobility, proliferation, and tumor killing capacity, validating ADAR1 as a target for enhancing NK immunotherapy
advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com/doi/10.1002/...
ZNF683+ NK cells overn chemotherapy sensitivity in advanced HPSCC via direct interaction with CD8 T & MHC-I-dependent licensing of polyfunctional GZMK+CD8+ Tem @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 22, 2026 at 9:24 PM
ZNF683+ NK cells overn chemotherapy sensitivity in advanced HPSCC via direct interaction with CD8 T & MHC-I-dependent licensing of polyfunctional GZMK+CD8+ Tem @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An Ebola virus glycoprotein mutant, which emerged early during the 2018–2020 epidemic, enhances viral infectivity through multiple mechanisms and may have contributed to its dominance in the outbreak @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
January 22, 2026 at 9:18 PM
An Ebola virus glycoprotein mutant, which emerged early during the 2018–2020 epidemic, enhances viral infectivity through multiple mechanisms and may have contributed to its dominance in the outbreak @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Peripheral cancer attenuates amyloid pathology in Alzheimer’s disease via cystatin-c activation of TREM2 @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
January 22, 2026 at 9:17 PM
Peripheral cancer attenuates amyloid pathology in Alzheimer’s disease via cystatin-c activation of TREM2 @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Neural-crest-derived facial fibroblasts upregulate SLIT2-ROBO2 signaling, a pathway important in neural crest cell biology, to promote wound healing with less fibrosis @cellcellpress.bsky.social @stanforduniversity.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
January 22, 2026 at 9:16 PM
Neural-crest-derived facial fibroblasts upregulate SLIT2-ROBO2 signaling, a pathway important in neural crest cell biology, to promote wound healing with less fibrosis @cellcellpress.bsky.social @stanforduniversity.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
January 22, 2026 at 9:12 PM
Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
RNA-mediated multimerization of MYC concentrates RNA-degrading factors around dsRNAs & R-loops, preventing aberrant RNAs from accumulating & leaking into cytosol, suppressing innate immunity to promote tumor growth @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
January 22, 2026 at 9:08 PM
RNA-mediated multimerization of MYC concentrates RNA-degrading factors around dsRNAs & R-loops, preventing aberrant RNAs from accumulating & leaking into cytosol, suppressing innate immunity to promote tumor growth @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Review @cellcellpress.bsky.social @sudpinglay.bsky.social @uwapress.uw.edu
Mammalian genome writing: Unlocking new length scales for genome engineering
www.cell.com/cell/fulltex...
Mammalian genome writing: Unlocking new length scales for genome engineering
www.cell.com/cell/fulltex...
January 22, 2026 at 9:05 PM
Review @cellcellpress.bsky.social @sudpinglay.bsky.social @uwapress.uw.edu
Mammalian genome writing: Unlocking new length scales for genome engineering
www.cell.com/cell/fulltex...
Mammalian genome writing: Unlocking new length scales for genome engineering
www.cell.com/cell/fulltex...
Commentary @cellcellpress.bsky.social: A two-tier framework for responsible research on human embryo models
www.cell.com/cell/fulltex... @crick.ac.uk @harvardmed.bsky.social @zernickagoetz.bsky.social
@caltech.edu @juliansavulescu.bsky.social @nusingapore.bsky.social @ox.ac.uk
www.cell.com/cell/fulltex... @crick.ac.uk @harvardmed.bsky.social @zernickagoetz.bsky.social
@caltech.edu @juliansavulescu.bsky.social @nusingapore.bsky.social @ox.ac.uk
January 22, 2026 at 9:04 PM
Commentary @cellcellpress.bsky.social: A two-tier framework for responsible research on human embryo models
www.cell.com/cell/fulltex... @crick.ac.uk @harvardmed.bsky.social @zernickagoetz.bsky.social
@caltech.edu @juliansavulescu.bsky.social @nusingapore.bsky.social @ox.ac.uk
www.cell.com/cell/fulltex... @crick.ac.uk @harvardmed.bsky.social @zernickagoetz.bsky.social
@caltech.edu @juliansavulescu.bsky.social @nusingapore.bsky.social @ox.ac.uk
@cellcellpress.bsky.social preview @larrysteinman.bsky.social @stanforduniversity.bsky.social @ucsfhealth.bsky.social
Discoveries beyond molecular mimicry describe how EBV drives multiple sclerosis
www.cell.com/cell/fulltex...
Discoveries beyond molecular mimicry describe how EBV drives multiple sclerosis
www.cell.com/cell/fulltex...
January 22, 2026 at 9:00 PM
@cellcellpress.bsky.social preview @larrysteinman.bsky.social @stanforduniversity.bsky.social @ucsfhealth.bsky.social
Discoveries beyond molecular mimicry describe how EBV drives multiple sclerosis
www.cell.com/cell/fulltex...
Discoveries beyond molecular mimicry describe how EBV drives multiple sclerosis
www.cell.com/cell/fulltex...
@cellcellpress.bsky.social preview: GigaTIME, an expansive population-scale analysis of the tumor immune microenvironment of over 14,000 patients across 24 cancer types, enabling clinical discovery and patient stratification
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
January 22, 2026 at 8:58 PM
@cellcellpress.bsky.social preview: GigaTIME, an expansive population-scale analysis of the tumor immune microenvironment of over 14,000 patients across 24 cancer types, enabling clinical discovery and patient stratification
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Platelet-derived growth factor receptor alpha regulates fetal testis differentiation via an ERK-CREB axis @cincyresearch.bsky.social #deFalco
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
January 22, 2026 at 6:54 PM
Platelet-derived growth factor receptor alpha regulates fetal testis differentiation via an ERK-CREB axis @cincyresearch.bsky.social #deFalco
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Butyrate emerges as a metabolite linking microbial metabolism to Tfh differentiation and IgA class switching
link.springer.com/article/10.1...
link.springer.com/article/10.1...
January 22, 2026 at 6:49 PM
Butyrate emerges as a metabolite linking microbial metabolism to Tfh differentiation and IgA class switching
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Waggoner Lab
Amazing work by our very talked student Yagmur Keser. Basal IFN are key to many epithelial functions.
Basal IFNλ2/3 signaling is required for ISG expression and viral control in human intestinal epithelial cells
@boulantlab.bsky.social @meganstanifer.bsky.social
journals.plos.org/plospathogen...
@boulantlab.bsky.social @meganstanifer.bsky.social
journals.plos.org/plospathogen...
January 22, 2026 at 4:52 PM
Amazing work by our very talked student Yagmur Keser. Basal IFN are key to many epithelial functions.
CD8+ T cell differentiation into NK-like effector cells drives transplant rejection @moltherapy.bsky.social
www.cell.com/molecular-th...
www.cell.com/molecular-th...
January 22, 2026 at 4:15 AM
CD8+ T cell differentiation into NK-like effector cells drives transplant rejection @moltherapy.bsky.social
www.cell.com/molecular-th...
www.cell.com/molecular-th...