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Dr Jo Jackson @jojacksonhere.bsky.social · Aug 1

A great week at #AAIC25. Thanks to @alzheimerssoc.bsky.social and @alzassociation.bsky.social for the opportunity!

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Dr Jo Jackson @jojacksonhere.bsky.social · Jul 29

Was fun...and hot 🥵

Alzheimer's Association @alzassociation.bsky.social · Jul 29

And they’re off! 🏃🏿‍♀️‍➡️🏃🏽‍♂️‍➡️🏃🏻‍♀️‍➡️ This morning, #AAIC25 attendees are enjoying stunning waterfront views as they make their way down Toronto’s scenic Martin Goodman Trail during our AAIC 5K Run/Walk.

Runners cross the starting line at the 5k fun run.

Runners run along the water with a sunrise background.

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Dr Jo Jackson @jojacksonhere.bsky.social · Jul 29

Come and hear about how the synaptic protein, SV2a, is not always found at synapses. To find out where else it is, come and see our group's poster #384 today. #AAIC25

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Dr Jo Jackson @jojacksonhere.bsky.social · Jul 27

Poster today #161

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Dr Jo Jackson @jojacksonhere.bsky.social · Jul 27

#AAIC25 Come and hear about synaptic proteomic changes over disease progression presented by the amazing Tatiana Georgiades in work funded by @alzheimerssoc.bsky.social

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Dr Jo Jackson @jojacksonhere.bsky.social · Jul 15

Sometimes I can't find it anywhere in the paper!

Dr Jo Jackson @jojacksonhere.bsky.social · Jul 3

This! Looking at my summer of deadlines whilst juggling childcare...😭

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Reposted by Dr Jo Jackson

Carlyle Group @bcarlylegroup.bsky.social · Jun 26

We have a new paper alert🎉

This work compiles all reported protein changes in the cerebrospinal fluid of Alzheimer’s patients across studies using mass spectrometry, Olink, and SomaScan platforms.

Check it out here:
academic.oup.com/braincomms/a...

#Alzheimers

A compilation of reported alterations in the cerebrospinal fluid proteome in Alzheimer's disease

de Geus et al. report that a compilation of CSF proteomics studies in Alzheimer’s disease identified 61 consistently altered proteins across mass spectrome

academic.oup.com

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Dr Jo Jackson @jojacksonhere.bsky.social · Jun 25

I feel seen 👀

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Dr Jo Jackson @jojacksonhere.bsky.social · May 7

Super proud of my PhD student, Tatiana, for being chosen as an @istaart.bsky.social Ambassador!

ISTAART @istaart.bsky.social · May 7

Delighted to welcome our new class of ISTAART Ambassadors for 2025! This year's 43 Ambassadors represent 27 countries across the globe. They'll work with us at #AAIC25 Toronto & online & we'll be mentoring them over the next year!

Meet them at alz.org/ISTAARTambassadors

@alzassociation.bsky.social

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Dr Jo Jackson @jojacksonhere.bsky.social · Apr 22

really looking forward to speaking in this session!

British Pharmacological Society @britpharmsoc.bsky.social · Apr 8

Join us at the @britishneuro.bsky.social Festival of Neuroscience 2025 (#BNA2025) where we'll deliver a joint workshop with @physoc.bsky.social on breakthroughs in treating #neurodegeneration!

Register now: meetings.bna.org.uk/bna2025/bna2...

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Dr Jo Jackson @jojacksonhere.bsky.social · Mar 30

Thought this for a while...they kill the vibe

Reposted by Dr Jo Jackson

Paresh Malhotra @pareshmalhotra.bsky.social · Mar 21

@imperialcollegeldn.bsky.social is looking for a new Head of Brain Sciences. Please repost and/or consider applying!!

www.imperial.ac.uk/jobs/search-...

Description

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

www.imperial.ac.uk

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Dr Jo Jackson @jojacksonhere.bsky.social · Mar 11

I've added you to the synapse starter pack...welcome!

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Dr Jo Jackson @jojacksonhere.bsky.social · Mar 6

Congratulations to my first Imperial PhD student Eleonore Schneegans! It's been a pleasure supervising you with Nurun Fancy and Paul Matthews. And thanks to the amazing examiners @sj-marzi.bsky.social and @ppetra.bsky.social. Pretty much an all woman dream team 😍

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Dr Jo Jackson @jojacksonhere.bsky.social · Feb 28

very cool, congrats!

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Dr Jo Jackson @jojacksonhere.bsky.social · Feb 28

Would be happy to help review

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Dr Jo Jackson @jojacksonhere.bsky.social · Feb 19

I seem to do all major work and life events together too...or maybe that's just adulting

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Dr Jo Jackson @jojacksonhere.bsky.social · Feb 14

Thanks for being such an awesome colleague! We will miss you but exciting times ahead for you!

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Reposted by Dr Jo Jackson

Dementia Researcher @dementiaresearcher.bsky.social · Feb 13

Dr Nurun Fancy at Imperial College London @imperialcollegeldn.bsky.social is seeking a PhD Student to explore the role of LRRK2 in cellular senescence in Parkinson's Disease. Closing date: 15th March #PhDPosition

www.dementiaresearcher.nihr.ac.uk/job/phd-role...

PhD: Role of LRRK2 in cellular senescence in Parkinson’s Disease

Dr Nurun Fancy at Imperial College London is seeking a PhD Student to explore the role of LRRK2 in cellular senescence in Parkinson's Disease

www.dementiaresearcher.nihr.ac.uk

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Reposted by Dr Jo Jackson

Vincent @vdion.bsky.social · Jan 29

I don’t think many of my American scientist friends will leave the US despite the recent political changes affecting the NIH.

But if they were interested, they should apply to become centre director here in Cardiff!

www.ukdri.ac.uk/vacancies/ce...

Centre Director, UK DRI at Cardiff

The UK Dementia Research Institute (UK DRI), principally funded by the Medical Research Council (MRC), and Cardiff University are seeking to appoint an outstanding established academic to a new Chair ...

www.ukdri.ac.uk

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Dr Jo Jackson @jojacksonhere.bsky.social · Jan 28

This opens up new synaptic tragets and avenues for the therapeutic targeting of synapses in AD. This was a great team effort by Jessica Griffiths joint with Seth Grant lab, Eleonore Scheegans and the UKDRI MAP team. The end. 6/6

Dr Jo Jackson @jojacksonhere.bsky.social · Jan 28

Taken together, we believe we have derived a pseudotemporal profile of synaptic changes in human AD and shown that they are associated with changes in the astrocyte proteome, particularly that of PAPs. 5/6

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Dr Jo Jackson @jojacksonhere.bsky.social · Jan 28

Alongside these synaptic changes, we found a astrcoyte signature that was enriched for proteins at the peri-synaptic astrocytic processes (PAPs). This astrocyte signature increased with pathology and was associated with reduced synaptic resilience. 4/6

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Dr Jo Jackson @jojacksonhere.bsky.social · Jan 28

Mitochondrial proteomic changes dominated in the low pathology region, inhibitory changes in the mid pathology region and widespread synaptic transmission pathways were most prominant in the higher pathology region. 3/6

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