Marla Feller
mfeller.bsky.social
Marla Feller
@mfeller.bsky.social

Neuroscientist, retinal circuits, neuro development. UC Berkeley

http://fellerlab.squarespace.com/

Marla Beth Feller is the Paul Licht Distinguished Professor in Biological Sciences and Member of the Helen Wills Neuroscience Institute at the University of California, Berkeley. She studies the mechanisms that underpin the assembly of neural circuits during development. Feller is a Fellow of the American Association for the Advancement of Science, member of the American Academy of Arts and Sciences and member of the National Academy of Sciences. .. more

Neuroscience 57%
Biology 33%

is that gray in that beard?

Self renewing pools of mitochondria at axon branch points to support those loooooong axons. great thread and fascinating finding from colleague @samlewis.bsky.social Congrats to all!

Reposted by Marla B. Feller

⚡️Mitochondria make ATP, the energy that powers life. But in neurons, with axons up to a meter long, how do these tiny power plants stay functional in the right places? We went looking. 1/n www.biorxiv.org/content/10.6...
Self-renewal of neuronal mitochondria through asymmetric division
Mitochondrial ATP production is essential for life. Mitochondrial function depends on the spatio-temporal coordination of nuclear and mitochondrial genome expression, yet how this coordination occurs ...
www.biorxiv.org

Reposted by Marla B. Feller

Studying vision across light levels? Interested in rod photoreceptors and related (patho)physiology? Matteo Rizzi, Kate Powell and I wrote a review on rod photoreceptor activity at daylight doi.org/10.1016/j.vi... . Free access link here kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

Reposted by Marla B. Feller

New preprint on sensory cortex dysfunction in Scn2a+/- mouse. Profoundly degraded sensory tuning and maps in S1--most dramatic of any ASD model. And rescued in post-critical period adults with CRISPRa.

www.biorxiv.org/content/10.6...
Degraded sensory coding in a mouse model of Scn2a-related disorder and its rescue by CRISPRa gene activation
Heterozygous loss-of-function mutations in SCN2A , a sodium channel gene expressed in cortical pyramidal (PYR) cells, lead to a neurodevelopmental disorder characterized by autism, intellectual disabi...
www.biorxiv.org

congrats to all!

Creative and important study for understanding visual processing.
Excited to share our new work on visual information processing in the retinocollicular pathway. We discovered that while luminance responses can predict motion responses in retinal ganglion cells, this prediction does not hold in the superior colliculus cells.

www.cell.com/current-biol...
Decoupling of visual feature selectivity in the retinocollicular pathway
Schwartz and Matsumoto et al. show that visual feature selectivity for luminance and motion is coupled in the retina but becomes decoupled in the superior colliculus. This transformation reorganizes t...
www.cell.com

Reposted by Marla B. Feller

Studying how mice see is giving neuroscientists new insight into how the human brain turns light into vision 👀

theconversation.com/gazing-into-... 🧪
Gazing into the mind’s eye with mice – how neuroscientists are seeing human vision more clearly
It was once believed that mice had relatively poor vision. Turns out mice are far from blind – and studying how their vision is shaped by their environment and behavior can clarify the same in people.
theconversation.com

Reposted by Marla B. Feller

Excited to share our new work on visual information processing in the retinocollicular pathway. We discovered that while luminance responses can predict motion responses in retinal ganglion cells, this prediction does not hold in the superior colliculus cells.

www.cell.com/current-biol...
Decoupling of visual feature selectivity in the retinocollicular pathway
Schwartz and Matsumoto et al. show that visual feature selectivity for luminance and motion is coupled in the retina but becomes decoupled in the superior colliculus. This transformation reorganizes t...
www.cell.com

Thanks @nicolecrust.bsky.social for forwarding the tweets and the perspective. What an incredible opportunity for an incredible scientist. Proud day for #neuroscience at @ucberkeleyofficial.bsky.social
This is HUGE! (Read it!!). I'll be cheering Doris and Astera Neuro on the entire way. Doris is a genius, both in the scope of her vision and in making things happen (that combination is rare). SO EXCITING! I can't wait to see what Astera Neuro discovers.

astera.org/neuroscienti...
Neuroscientist Doris Tsao joins Astera to lead its new neuroscience program - Astera
The Astera Institute is excited to launch a major new neuroscience research effort led by Dr. Doris Tsao, who will be joining as Chief Scientist for Astera Neuro. We seek to understand one of the deep...
astera.org

Reposted by Marla B. Feller

This is HUGE! (Read it!!). I'll be cheering Doris and Astera Neuro on the entire way. Doris is a genius, both in the scope of her vision and in making things happen (that combination is rare). SO EXCITING! I can't wait to see what Astera Neuro discovers.

astera.org/neuroscienti...
Neuroscientist Doris Tsao joins Astera to lead its new neuroscience program - Astera
The Astera Institute is excited to launch a major new neuroscience research effort led by Dr. Doris Tsao, who will be joining as Chief Scientist for Astera Neuro. We seek to understand one of the deep...
astera.org

Reposted by Marla B. Feller

Our story on mechanosensation in baroreceptor cells of the kidney is finally out! Well worth the wait on this project we began in 2020 that turned into a massive collaborative effort within the kidney field. 🫘 www.sciencedirect.com:5037/science/arti...
www.sciencedirect.com
Check out the newest Editors' (that would be me and Eunjoon Kim) Choice issue in Current Opinion in Neurobiology.

Superbly guest edited by Stephen Liberles and @zknight.bsky.social

>20 review articles on Interoception

www.sciencedirect.com/special-issu...
Current Opinion in Neurobiology | Interoception 2025 | ScienceDirect.com by Elsevier
Read the latest articles of Current Opinion in Neurobiology at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com

Reposted by Marla B. Feller

Announcing the Inaugural Fluorescence Advanced Imaging Research Workshop
sites.uci.edu/aimlfdworksh... A joint effort between UC Berkeley and UC Irvine, bringing together the cutting edge talks of AIM and the intensive hands-on experience of the LFD Workshop. #microscopy #fluorescence
LFD/AIM Workshop 2026
sites.uci.edu

I cannot stop thinking about this video....heartbreaking. Thank you for sharing.

There is a matching campaign today for the Berkeley Basic Needs Center to help @ucberkeleyofficial.bsky.social students dealing with reduced CalFresh (SNAP) benefits. Give if you can! crowdfund.berkeley.edu/project/48580
Support Basic Needs at Berkeley!
Help UC Berkeley students access food during the government shutdown.
crowdfund.berkeley.edu

fantastic - congratulations!

Reposted by Marla B. Feller

We’re hiring! Join the Sivyer Lab at The University of Sydney as a Postdoctoral Research Fellow in Neurodegeneration within the Snow Vision Accelerator, a $50M initiative tackling glaucoma and optic nerve disease. iPSCs, electrophysiology, drug discovery, and gene therapy.

Reposted by Marla B. Feller

Excited to share our paper now published in Cell!
'Zebrafish use spectral information to suppress the visual background'

Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social

@cellpress.bsky.social @cp-cell.bsky.social

👇🏻
www.cell.com/cell/fulltex...
Zebrafish use spectral information to suppress the visual background
Vertebrate eyes first evolved in water, where spectral content rapidly fades with distance. Zebrafish exploit this loss by antagonizing cone signals to suppress the background, pointing to distance es...
www.cell.com

Reposted by Marla B. Feller

Molecular & Cellular Physiology (MCP) Monday

We are recruiting a tenure-track assistant professor to join the Dept of Molecular & Cellular Physiology at Stanford. Apply to be our colleague. Please repost. 1/n
facultypositions.stanford.edu/en-us/job/49...
facultypositions.stanford.edu

Run-roh! Dr. Karina Bistrong’s last day in the lab. It was celebrated Scooby-Doo style 🐾🔍 She’s off to NYU for a postdoc with the exciting new lab run by @[email protected] — onward to solving the mysteries of motor systems!

💔🧠

miriam! thanks for letting us know the sad news and for the great photo.

Reposted by Marla B. Feller

Neuroscientists say No Kings

Appreciating the art with fellow @annualreviews.bsky.social for vision science board members Roland Fleming and @shinyanishida.bsky.social .

din’t miss the video!!

AMAZING!! 🎉👏👁️🧠🤓
Teresa Puthussery, a UC Berkeley vision scientist whose insights into the retina could one day help those with vision loss regain their sight, has been named a 2025 MacArthur “genius” Fellow. news.berkeley.edu/2025/10/08/v...
Vision scientist Teresa Puthussery receives MacArthur ‘genius’ award - Berkeley News
Puthussery’s discoveries about the retina are paving the way for new treatments for eye disease and vision loss
news.berkeley.edu

Reposted by Marla B. Feller

Teresa Puthussery, a UC Berkeley vision scientist whose insights into the retina could one day help those with vision loss regain their sight, has been named a 2025 MacArthur “genius” Fellow. news.berkeley.edu/2025/10/08/v...
Vision scientist Teresa Puthussery receives MacArthur ‘genius’ award - Berkeley News
Puthussery’s discoveries about the retina are paving the way for new treatments for eye disease and vision loss
news.berkeley.edu

Reposted by Marla B. Feller

Timely piece on the importance and safety of “gain-of-function” research, from my brilliant PhD advisor Sarah Stanley www.statnews.com/2025/10/06/g...
The NIH ordered me to stop my ‘dangerous’ gain-of-function research. It isn’t dangerous at all
Safe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis — but the NIH has imposed unfounded stops.
www.statnews.com

Reposted by Marla B. Feller

The 2025 volume of the Annual Review of Vision Science is now online. The most read article so far is "Behavior-Specific Computations in the Vertebrate Retina" arevie.ws/46HMEjd @serenariccitelli.bsky.social @annaintegrated.bsky.social @katrinfranke.bsky.social

TOC: arevie.ws/3Wklava