De 38-jarige Sanne van Enckevort uit Hegelsom is levensbedreigend verzwakt, maar krijgt geen toegang tot intraveneuze voeding. Ondanks medische noodzaak wijzen ziekenhuizen de behandeling af, mede van...

Yes, epigenetic changes can often be reverted, as they involve modifications to gene expression without altering the DNA sequence itself. These changes, such as DNA methylation or histone modification, are dynamic and can be influenced by environmental factors, lifestyle, or therapeutic interventions. For example: Lifestyle and Environmental Factors: Diet (e.g., folate or B-vitamin intake), exercise, stress reduction, and exposure to certain chemicals can reverse epigenetic marks like methylation patterns. Pharmacological Interventions: Drugs like DNA methyltransferase inhibitors (e.g., azacitidine) or histone deacetylase inhibitors can reverse aberrant epigenetic modifications, often used in cancer treatments. Developmental Plasticity: Some epigenetic changes are naturally reversible during specific developmental windows or in response to cellular signals. However, the reversibility depends on the type, timing, and context of the epigenetic change. Some marks, especially those established early in development or in certain diseases, may be more stable and harder to reverse. Research is ongoing to better understand the mechanisms and limits of epigenetic reversibility.

Research could offer hope for ME patients – but some experts urge caution and say more studies needed

Research could offer hope for ME patients – but some experts urge caution and say more studies needed

The first results of DecodeME are in, the largest research project ever undertaken on myalgicContinue readingDecodeME: the biggest ME/CFS study ever

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A former PM, tech tycoon Larry Ellison and Britain's data - what could go wrong?

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Once, I believed that humanity’s problem was an information deficit. Now, I know you can’t speak truth to power if power controls your words, says Guardian columnist George Monbiot