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Organic Chemistry Portal @organicportal.bsky.social · 14h

www.organic-chemistry.org/Highlights/2...
Douglass features Substituted Benzenes: The Xie Synthesis of Cephanolide B

Organic Chemistry Portal @organicportal.bsky.social · 14h

Molecule of the week: Cephanolide B
The cephanolide diterpenoids isolated from the Chinese plum yew Cephalotaxus sinensis, exemplified by cephanolide B, show antineoplastic, antiviral and antitumor properties.
More Info: www.organic-chemistry.org/Highlights/2...

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Organic Chemistry Portal @organicportal.bsky.social · 2d

www.organic-chemistry.org/abstracts/li...
A mild and efficient electrochemical protocol provides quinazolines through N-H/C(sp3)-H coupling of o-carbonyl anilines with natural amino acids/amines

Organic Chemistry Portal @organicportal.bsky.social · 2d

www.organic-chemistry.org/abstracts/li...
Zirconocene hydride catalyzes a mild method for the semireduction of both secondary and tertiary amides to imines.

Organic Chemistry Portal @organicportal.bsky.social · 2d

www.organic-chemistry.org/abstracts/li...
A low-barrier photoinduced ligand to metal charge transfer (LMCT) enables a radical decarboxylative carbometalation strategy.

Organic Chemistry Portal @organicportal.bsky.social · 2d

www.organic-chemistry.org/abstracts/li...
A bench-stable (1-phosphoryl)vinyl sulfonate reagent enables a one-step homologation of carboxylic acids under mild conditions.

Organic Chemistry Portal @organicportal.bsky.social · 2d

www.organic-chemistry.org/abstracts/li...
Irradiating 3-silyl-1,4-cyclohexadienes with blue light in the presence of a commercially available photocatalyst smoothly generated silyl radicals

Organic Chemistry Portal @organicportal.bsky.social · 2d

www.organic-chemistry.org/abstracts/li...
A metal-free C(sp3)-H aroylation of amines via visible-light photoredox catalysis provides useful α-amino aryl ketones.

Organic Chemistry Portal @organicportal.bsky.social · 2d

www.organic-chemistry.org/abstracts/li...
A cyclometalated ruthenium(II)-complex catalyzes a selective oxidative scission of olefins to carbonyl compounds.

Organic Chemistry Portal @organicportal.bsky.social · 2d

www.organic-chemistry.org/abstracts/li...
A simple and efficient base-mediated decarboxylative annulation of ynones with methyl 2-(2-bromophenyl)acetates

Organic Chemistry Portal @organicportal.bsky.social · 2d

www.organic-chemistry.org/abstracts/li...
A facile and mild method for the preparation of 2,3-dialkyl-substituted quinazolinones

Organic Chemistry Portal @organicportal.bsky.social · 3d

We have just published a vacancy for a Process Chemistry Senior Principal Scientist at Vertex, Boston, MA, USA: www.organic-chemistry.org/jobs/offers/... - Please check and share!

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Organic Chemistry Portal @organicportal.bsky.social · 3d

www.organic-chemistry.org/abstracts/li...
Additions of α-boryl-substituted allylboronate to aldehydes provide 1,2-oxaborinan-3-enes.

Organic Chemistry Portal @organicportal.bsky.social · 3d

www.organic-chemistry.org/abstracts/li...
A (pyridyl)phosphine-ligated ruthenium(II) catalyzes a diol-diamine coupling to provide piperazines and diazepanes.

Organic Chemistry Portal @organicportal.bsky.social · 3d

www.organic-chemistry.org/abstracts/li...
An alkyne deprotonation/boronation/oxidation sequence for a one-pot γ-lactonization of homopropargyl alcohols

Organic Chemistry Portal @organicportal.bsky.social · 3d

www.organic-chemistry.org/abstracts/
Today, we have just featured: Platinum-Catalyzed Diboration of Alkynes by B2(dan)2, Three-Component Oxychalcogenation of Alkenes under Metal-Free Conditions; Sodium Aminodiboranate, a New Reagent for Chemoselective Reduction of Aldehydes and Ketones to Alcohols

Organic Chemistry Portal @organicportal.bsky.social · 4d

www.organic-chemistry.org/abstracts/li...
A decarboxylative cyanomethylation of β-aryl/heteroaryl substituted α,β-unsaturated carboxylic acids

Organic Chemistry Portal @organicportal.bsky.social · 4d

www.organic-chemistry.org/abstracts/li...
Use of a nickel catalyst in combination with a photoredox catalyst and light leads to much more active alkylation catalysts

Organic Chemistry Portal @organicportal.bsky.social · 4d

www.organic-chemistry.org/abstracts/li...
Visible-light-induced singlet nucleophilic carbene intermediates can be trapped by fluorinated ketones via 1,2-carbonyl addition

Organic Chemistry Portal @organicportal.bsky.social · 4d

The video of the announcement: www.youtube.com/watch?v=0d02... For more information, please also check out our other posts here. And I'm sure we'll cover some catalytically active MOFs in the future as part of our project.

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Organic Chemistry Portal @organicportal.bsky.social · 4d

For a concise introduction to the chemistry and design principles behind important metal-organic frameworks and related porous materials, we recommend the book authored by Omar M. Yaghi et al: Americas: amzn.to/4mYd5Y6 , EU: amzn.to/3VShKjp , UK: amzn.to/3KDDIUU

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Organic Chemistry Portal @organicportal.bsky.social · 4d

separating PFAS from water, breaking down traces of pharmaceuticals in the environment, capturing carbon dioxide or harvesting water from desert air.
www.nobelprize.org/prizes/chemi...

Nobel Prize in Chemistry 2025

The Nobel Prize in Chemistry 2025 was awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks.”

www.nobelprize.org

Organic Chemistry Portal @organicportal.bsky.social · 4d

Following the laureates’ groundbreaking discoveries, chemists have built tens of thousands of different MOFs. Some of these may contribute to solving some of humankind’s greatest challenges, with applications that include...

Nobel Prize in Chemistry 2025

The Nobel Prize in Chemistry 2025 was awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks.”

www.nobelprize.org

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Organic Chemistry Portal @organicportal.bsky.social · 4d

Metal-organic frameworks have enormous potential, bringing previously unforeseen opportunities for custom-made materials with new functions,” says Heiner Linke, Chair of the Nobel Committee for Chemistry.

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Organic Chemistry Portal @organicportal.bsky.social · 4d

The Nobel Prize in Chemistry has just been awarded to Susumu Kitagawa, Kyoto University, Japan; Richard Robson, University of Melbourne, Australia and Omar M. Yaghi, University of California, Berkeley, USA for "the development of metal-organic frameworks. www.nobelprize.org/prizes/chemi...

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