SchurichLab
@schurichlab.bsky.social
390 followers
46 following
4 posts
Research group interested in T cell immunometabolism and advanced therapies
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SchurichLab
@schurichlab.bsky.social
· Jul 17
CAR-T cells containing CD28 versus 4-1BB co-stimulatory domains show distinct metabolic profiles in patients
Cook et al. investigate the metabolic profile of DLBCL patient-derived CAR-T cells
ex vivo. Comparing Axi-cel (CD28-co-stimulated) and Tisa-cel (4-1BB-co-stimulated)
products, they find divergent meta...
www.cell.com
Reposted by SchurichLab
SchurichLab
@schurichlab.bsky.social
· Apr 30
Reposted by SchurichLab
Christian Frezza
@frezzalab.bsky.social
· Mar 30
Running a genetic stop sign accelerates oxygen metabolism and energy production in horses
Horses are among nature’s greatest athletes, yet the ancestral molecular adaptations fueling their energy demands are poorly understood. Within a clinically important pathway regulating redox and meta...
www.science.org
Reposted by SchurichLab
Dan Jagger
@auditorynerves.bsky.social
· Mar 24
A French university is offering ‘scientific asylum’ for US talent. The brain drain has started | Alexander Hurst
The Trump administration is cutting funding, while specifically targeting institutions like Columbia. No wonder academics want out, says Guardian Europe columnist Alexander Hurst
www.theguardian.com
SchurichLab
@schurichlab.bsky.social
· Mar 24
Reposted by SchurichLab
Reposted by SchurichLab
Reposted by SchurichLab
Christian Frezza
@frezzalab.bsky.social
· Mar 20
Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism
Wang et al. reveal that DLAT, a pyruvate metabolism enzyme, modulates leucine metabolism
by directly acetylating the leucine catabolism enzyme AUH at K109, leading to leucine
accumulation and sustaine...
www.cell.com
SchurichLab
@schurichlab.bsky.social
· Mar 11
Reposted by SchurichLab
Reposted by SchurichLab
Reposted by SchurichLab
Robin Lacassin
@rlacassin.bsky.social
· Feb 28
Trump’s war on climate science is pushing us into a dystopian future
Withdrawing support for research and scrubbing climate data from US government websites has repercussions for Australia and the world. But there are ways around it.
theconversation.com