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Khaled_Selim Lab

@selimlab.bsky.social

270 followers 270 following 140 posts

Microbiology | Cell Signaling | Structural Biology | Institute of Phototrophic Microbiology @hhu.de https://www.phototrophic-microbiology.hhu.de/en/ Central Metabolism Coordination by #PII & #cdiAMP & #cdiGMP & #Ca2+ signaling #Cyanobacteria

www.phototrophic-microbiology.hhu.de

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Khaled_Selim Lab @selimlab.bsky.social · 21d

We discovered a new family of c-di-NMP receptors, widespread in bacteria & regulating🦠motility @pnas.org

A great collab. w/ @mygalperin.bsky.social @vikramalva.bsky.social @thethormannden.bsky.social

www.pnas.org/doi/10.1073/...

@hhu.de @cmfi.bsky.social
@sfb1381.bsky.social
@mibinet.bsky.social

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Reposted by Khaled_Selim Lab

ETH Zurich @ethz.ch · 8h

All cells – from mammalian cells to microbes – can follow different biological paths. Whether they grow and divide, specialise, age or die depends on the pathway they take. New findings by researchers at ETH Zurich could help influence a cell’s decisions to target diseases such as cancer.

Protein condensates determine a cell’s fate

Do cells contain a mechanism that decides on their fates? Researchers at ETH Zurich have demonstrated in a new study that large clusters of molecules determine a cell’s future.

ethz.ch

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Reposted by Khaled_Selim Lab

GBM (Gesellschaft für Biochemie und Molekularbiologie) @gbmev.bsky.social · 1d

Registration open: 77. Mosbacher Kolloquium "More than lipidic barriers - New horizons in membrane biology" from March 25-28, 2026
lnkd.in/dgsW4c3

Scientific Organizers: Britta Brügger, Robert Ernst, André Nadler, Christian Ungermann
Early registration & poster abstracts until January 31, 2026

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Khaled_Selim Lab @selimlab.bsky.social · 2d

Plz re-post

A wonderful place to be...
Come and join us a group leader position in „Phage Biology & Biotechnology“.

www.fz-juelich.de/de/karriere/...
Get in touch with @frunzkelab.bsky.social for more information

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Khaled_Selim Lab @selimlab.bsky.social · 2d

This add on to the functional catalog of #cdiAMP by showing it's involvement in ROS balance, photosyn., motility & proteome stability to regulate day-night switches in #cyano

part of this work was done by my former PhD, Michael Haffner @cmfi.bsky.social and some support by @sfb1381.bsky.social ...

Khaled_Selim Lab @selimlab.bsky.social · 2d

A bit late 🙃 but happy to share our recent findings on #cdiAMP signaling in controlling #cyanobacteria #diurnal rhythm in @cp-iscience.bsky.social

www.cell.com/iscience/ful...

#cdiAMP is involved in almost all cellular processes, explaining it's essentiality in #cyano
@hhu.de
@mibinet.bsky.social

Diurnal rhythm causes metabolic crises in the cyanobacterial mutants of c-di-AMP signaling cascade

Biological sciences; Biochemistry; Microbiology; PII-like protein SbtB; c-di-AMP signaling; Cyanobacteria; Carbon/Nitrogen metabolism; Redox imbalance; Photosynthesis; Reactive oxygen species (ROS); C...

www.cell.com

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Reposted by Khaled_Selim Lab

Patricia Bernal @pbernalt6ss.bsky.social · 3d

Our paper, describing how the T6SSs of P. putida shape the tomato rhizosphere, is now in its final format in @isme-microbes.bsky.social ISME Communications. If you'd like to learn more, here is a thread (1/11) or read the Article doi.org/10.1093/isme....

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Khaled_Selim Lab @selimlab.bsky.social · 3d

He found another one of a bacterium with mitochondrial dysfunction
I don't know if I should laugh 😂 or cry 😭 ....

@mdpiopenaccess.bsky.social

www.mdpi.com/2079-6382/14...

Reposted by Khaled_Selim Lab

Molecular Microbiology @molmicrounihoh.bsky.social · 4d

Humans began travelling into space in 1961 with single orbits of the Earth. Now Bacillus subtilis!

👉

www.nature.com/articles/s41...

#subtiwiki

Thank you @joergstuelke.bsky.social for the reading recommendation!

Effects of extreme acceleration, microgravity, and deceleration on Bacillus subtilis onboard a suborbital space flight - npj Microgravity

npj Microgravity - Effects of extreme acceleration, microgravity, and deceleration on Bacillus subtilis onboard a suborbital space flight

www.nature.com

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Khaled_Selim Lab @selimlab.bsky.social · 4d

Here's the original comment:

pubpeer.com/publications...

PubPeer - Nanotechnology-Enhanced Orthopaedic Surgery

There are comments on PubPeer for publication: Nanotechnology-Enhanced Orthopaedic Surgery (2024)

pubpeer.com

Khaled_Selim Lab @selimlab.bsky.social · 4d

Bacterial 🦠 mitochondria 🙈 .... What a shit 😅

@sholtodavid.bsky.social pointed in X for an "unreviewed" article with status officially reviewed in @mdpiopenaccess.bsky.social

Maybe it's AI generated with no efforts from authors, editors or reviewers to go through it?

www.mdpi.com/2624-845X/5/...

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Khaled_Selim Lab @selimlab.bsky.social · 4d

Very interesting work for maintaining synthetic microbial consortia

www.nature.com/articles/s41...

@mibinet.bsky.social

Long-term homeostasis in microbial consortia via auxotrophic cross-feeding - Nature Communications

Synthetic microbial consortia are collections of strains which can segregate metabolic tasks for efficient use in biomaterials, biomanufacturing, and biotherapeutics. Here, the authors present a method to maintain and tune the ratio of two co-cultured bacterial strains via growth medium manipulation.

www.nature.com

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Khaled_Selim Lab @selimlab.bsky.social · 5d

Synthetic Horizontal Gene Transfer for Ecosystem Restoration

www.biorxiv.org/content/10.1...

Synthetic Horizontal Gene Transfer for Ecosystem Restoration

Restoring endangered ecosystems has become a pressing issue as the effects of global warming continue to harm existing communities. Over the last decade, several studies have suggested the use of synt...

www.biorxiv.org

Reposted by Khaled_Selim Lab

Daumann Lab @daumannl.bsky.social · 6d

Video compilation from our #türenauf mit der Maus Tag today! #outreach #chemsky @hhu.de @sophieguti.bsky.social @joguti.bsky.social @markussuta.bsky.social @chemiehhu.bsky.social

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Reposted by Khaled_Selim Lab

Tung Le @tunglejic.bsky.social · 6d

Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!

John Innes Centre @johninnescentre.bsky.social · 7d

Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.

Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.

Find out more: www.jic.ac.uk/training-car...

Independent Research Fellowships Leading to Tenured Faculty Positions | John Innes Centre

The John Innes Centre (JIC), is a world leading centre of excellence in plant and microbial sciences based on the Norwich Research Park, UK. We are inviting applications from outstanding researchers…

www.jic.ac.uk

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Reposted by Khaled_Selim Lab

Ben Long @botbml.bsky.social · 7d

arxiv.org/abs/2509.23445

Uncertainty Quantification of Bacterial Microcompartment Permeability

$\textit{Salmonella}$ expresses bacterial microcompartments (MCPs) upon 1,2-propanediol exposure. MCPs are nanoscale protein-bound shells that encase enzymes for the cofactor-dependent 1,2-propanediol...

arxiv.org

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Reposted by Khaled_Selim Lab

Erin Doherty @erinedoherty.bsky.social · 8d

And thanks to @mfwhite2.bsky.social for this great perspective on both works! www.nature.com/articles/d41...

Bacteria use a decoy defence molecule to set a trap for viruses

Some bacterial-infecting viruses use ‘sponges’ to mop up defence molecules, but bacteria can fight back by responding when a sponge captures decoy molecules.

www.nature.com

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Reposted by Khaled_Selim Lab

Ben Adler @benadler.bsky.social · 8d

Today in @nature.com , we highlight how a cousin of CRISPR-Cas10, mCpol, establishes an evolutionary trap in anti-phage immune systems.

Check out @erinedoherty.bsky.social and my work from @doudna-lab.bsky.social lab here:
www.nature.com/articles/s41...

A miniature CRISPR–Cas10 enzyme confers immunity by inhibitory signalling - Nature

Panoptes, an anti-phage defence system against virus-mediated immune suppression, is revealed.

www.nature.com

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Reposted by Khaled_Selim Lab

Ben Morehouse @benmorehouse.bsky.social · 8d

Our story describing the Panoptes bacterial immune defense system is now finally peer-reviewed and published today! www.nature.com/articles/s41...

The Panoptes system uses decoy cyclic nucleotides to defend against phage - Nature

The Panoptes antiphage system defends bacteria by detecting phage-encoded counter-defences that sequester cyclic nucleotide signals, triggering membrane disruption and highlighting a broader strategy of sensing immune evasion through second-messenger surveillance.

www.nature.com

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Khaled_Selim Lab @selimlab.bsky.social · 9d

Keep rocking...
It's hard but you'll do it if you have patience and passion ;-)

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Khaled_Selim Lab @selimlab.bsky.social · 9d

Also in Spanish ;-)

larepublica.es/2025/09/27/d...

Descubren nuevos mecanismos que regulan la motilidad y transferencia de ADN en bacterias

Investigaciones recientes realizadas por un equipo de científicos en colaboración con diversas universidades y centros de investigación han revelado nuevos mecanismos que regulan la motilidad bacteria...

larepublica.es

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Khaled_Selim Lab @selimlab.bsky.social · 10d

Congrats Gabriel & Florian!
@faltegoer.bsky.social
Cool piece of work ....

Khaled_Selim Lab @selimlab.bsky.social · 10d

Here's the German version
@hhu.de

Mechanismus für die Beweglichkeit und den DNA-Transfer zwischen Bakterien entschlüsselt

www.hhu.de/news-einzela...
@cmfi.bsky.social @mibinet.bsky.social @sfb1381.bsky.social

Biologie: Veröffentlichungen in Cell Discovery und PNAS

Bakterien bewegen sich mithilfe von Bewegungsorganen, sogenannten Flagellen oder Pili, ständig fort, um neue Nischen zu besiedeln. Außerdem können sie durch den Austausch von DNA-Strängen Informatione...

www.hhu.de

Reposted by Khaled_Selim Lab

Biozentrum, University of Basel @biozentrum.unibas.ch · 11d

Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging

www.biozentrum.unibas.ch/open-positio...

#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging

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Khaled_Selim Lab @selimlab.bsky.social · 11d

New Insights Into Bacterial Motility and DNA Transfer:
a small press on our discovery of ComFB signaling family by @claussenarne.bsky.social @hhu.de

www.eurekalert.org/news-release...
w/ @mygalperin.bsky.social @thethormannden.bsky.social
@cmfi.bsky.social @mibinet.bsky.social @sfb1381.bsky.social

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Khaled_Selim Lab @selimlab.bsky.social · 14d

Next time then ...