UCL Queen Square Institute of Neurology
@uclqsion.bsky.social
650 followers 150 following 48 posts
We are a world-leading centre for neurological research within the UCL Faculty of Brain Sciences. www.ucl.ac.uk/brain-sciences/ion
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uclqsion.bsky.social
We're excited to join BlueSky! Make sure to follow us for the latest news from the UCL Queen Square Institute of Neurology.
graphic launching UCL Queen Square Institute of Neurology on Blue Sky
Reposted by UCL Queen Square Institute of Neurology
reza-maroofian.bsky.social
Our EPG5 study shows a continuum: early neurodevelopmental disruption and adult-onset neurodegeneration, both tied by autophagy defects. Like GBA1, PLA2G6, WDR45 & SYNJ1, PSMF1, EPG5 links rare paediatric disorders to adult PD/dementia. Rare informing common. bit.ly/432N7LT @UCLIoN @UCLBrainScience
Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early‐Onset Parkinsonism
Objective Autophagy is a fundamental biological pathway with vital roles in intracellular homeostasis. During autophagy, defective cargoes including mitochondria are targeted to lysosomes for cleara...
bit.ly
Reposted by UCL Queen Square Institute of Neurology
uclenterprise.bsky.social
The latest UCL newsletter is out!

Read about UCL being rated as a leading university for knowledge exchange five years in a row by Research England, the UCL gene therapy trial which appears to slow Huntington’s disease progression and more: bit.ly/4mWYI6g
UCL News September 2025
Reposted by UCL Queen Square Institute of Neurology
uclnews.bsky.social
Motor neurone disease progresses at a different rate in each individual, @ucl.ac.uk’s Prof Andrea Malaspina tells @skynewsrss.bsky.social following the news that former England rugby captain & World Cup winner Lewis Moody has been diagnosed with the condition @uclbrainscience.bsky.social
Reposted by UCL Queen Square Institute of Neurology
royalsociety.org
Join Royal Society Ferrier Prize winner Professor Gillian Bates FRS on 06 October at the Royal Society as she unravels the molecular basis of Huntington's disease: royalsociety.org/science-even...
Reposted by UCL Queen Square Institute of Neurology
ukdri.ac.uk
Recording now available from this week's 'Rethinking neurodegeneration' research webinar with the brilliant Profs Sarah Tabrizi (UK DRI at UCL) and Gabriel Balmus (UK DRI at Cambridge) discussing DNA repair and Huntington's

Catch up now if you missed it 👉 youtu.be/cXsrYM2Fq7g?...
Rethinking neurodegeneration: Could DNA repair hold the key to treating Huntington's disease?
YouTube video by UK Dementia Research Institute - UK DRI
youtu.be
Reposted by UCL Queen Square Institute of Neurology
royalsociety.org
We're very happy to announce that the winner of this year’s Royal Society Trivedi Science Book Prize is ‘Our Brains, Our Selves: What a Neurologist’s Patients Taught Him About the Brain’ by debut author, clinical neurologist and neuroscientist Masud Husain. #SciBooks royalsociety.org/news/2025/10...
Reposted by UCL Queen Square Institute of Neurology
uclbrainscience.bsky.social
“This would have been such a massive deal for her."
Anna Sheahan's mum sadly died of Huntington's disease (HD) last year.
Anna speaks to The Observer about what @uclqsion.bsky.social's HD breakthrough means to families like hers:
Mum died of Huntington’s... this breakthrough changes eve...
A professor battling to slow the disease that killed writer Charlotte Raven shared his good news with her daughter
observer.co.uk
Reposted by UCL Queen Square Institute of Neurology
Reposted by UCL Queen Square Institute of Neurology
Reposted by UCL Queen Square Institute of Neurology
Reposted by UCL Queen Square Institute of Neurology
uclnews.bsky.social
A team involving @uclqsion.bsky.social and @crick.ac.uk scientists has, for the first time, directly visualised and quantified the protein clusters believed to trigger Parkinson’s disease, with a technique that could support the development of diagnostics and treatments for Parkinson’s in the future
Parkinson’s ‘trigger’ directly observed in human brain tissue for the first time
A team involving UCL scientists has, for the first time, directly visualised and quantified the protein clusters believed to trigger Parkinson’s disease.
www.ucl.ac.uk
Reposted by UCL Queen Square Institute of Neurology
uclbrainscience.bsky.social
🧠 🧵 Our September news roundup is here!
It's been a month of incredible scientific breakthroughs at the Faculty of Brain Sciences.
Let's check out some of the stories making headlines around the world.👇 👇 👇
Reposted by UCL Queen Square Institute of Neurology
ukdri.ac.uk
🎉 We are delighted to announce that Professor Karen Duff (UK DRI at UCL) has been awarded funding for frontotemporal dementia (FTD) research

From uncovering disease mechanisms to testing therapeutic strategies, Karen’s team aim to shed light on how FTD develops

Read more 👉 tinyurl.com/78f8fuxk
Reposted by UCL Queen Square Institute of Neurology
Reposted by UCL Queen Square Institute of Neurology
acmedsci.bsky.social
Former Academy SUSTAIN participant Dr Lauren Byrne, a Principal Research Fellow @uclbrainscience.bsky.social, speaks candidly about this week's Huntington's disease treatment breakthrough, given her close family experience of the disease.

Read more 👇
www.bbc.co.uk/news/article...
Huntington's disease breakthrough 'amazing' but with 'caveats'
The new treatment is a type of gene therapy given during 12 to 18 hours of delicate brain surgery.
www.bbc.co.uk
Reposted by UCL Queen Square Institute of Neurology
imagingneuroucl.bsky.social
#BrainMeeting 🧠 Alert!

This Friday, October 3rd, the brain meeting speaker will be Prof Li Su giving a talk entitled "Digital twin models that talk the talk and walk the walk"

All welcome, in person or online. For more information:
www.fil.ion.ucl.ac.uk/event
Reposted by UCL Queen Square Institute of Neurology
russellgroup.bsky.social
Amazing news from @ucl-hd.bsky.social @ucl.ac.uk hitting the headlines this week. A new form of gene therapy has successfully treated Huntington's Disease for the first time ever, slowing the disease by 75%.

This university research is changing lives.

Read more on BBC News ⬇️