Borja Ibarra
@3mlab.bsky.social
www.borjaibarralab.com
Our lab is interested in single-molecule biochemistry, mitochondrial DNA replication, single molecule supramolecular chemistry, and more...
IMDEA Nanoscience, Madrid, Spain
Our lab is interested in single-molecule biochemistry, mitochondrial DNA replication, single molecule supramolecular chemistry, and more...
IMDEA Nanoscience, Madrid, Spain
Pinned
Borja Ibarra
@3mlab.bsky.social
· Feb 7
We are hiring!
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
Hey there Bluesky!
Postdoctoral position in Single-Molecule Biophysics of Mitochondrial DNA Replication still open! ☺️
An interdisciplinary effort to uncover mitochondrial replisome dynamics and the molecular origins of disease-related mutations @imdeananociencia.bsky.social 👇👇
Postdoctoral position in Single-Molecule Biophysics of Mitochondrial DNA Replication still open! ☺️
An interdisciplinary effort to uncover mitochondrial replisome dynamics and the molecular origins of disease-related mutations @imdeananociencia.bsky.social 👇👇
June 19, 2025 at 2:54 PM
Hey there Bluesky!
Postdoctoral position in Single-Molecule Biophysics of Mitochondrial DNA Replication still open! ☺️
An interdisciplinary effort to uncover mitochondrial replisome dynamics and the molecular origins of disease-related mutations @imdeananociencia.bsky.social 👇👇
Postdoctoral position in Single-Molecule Biophysics of Mitochondrial DNA Replication still open! ☺️
An interdisciplinary effort to uncover mitochondrial replisome dynamics and the molecular origins of disease-related mutations @imdeananociencia.bsky.social 👇👇
Reposted by Borja Ibarra
The position will stay open untill we find the rigth candidate.
May 14, 2025 at 7:08 AM
The position will stay open untill we find the rigth candidate.
Reposted by Borja Ibarra
We are hiring!
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
February 7, 2025 at 3:28 PM
We are hiring!
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
Reposted by Borja Ibarra
A una molecula le "cuesta" lo mismo subir que bajar la barrera energética entre dos estados metaestables. @emiliomperezlab.bsky.social @3mlab.bsky.social lo observan por primera vez en nanomaquinas moleculares 👉
phys.org/news/2025-02...
phys.org/news/2025-02...
Optical tweezers reveal forward and backward motion is symmetric in molecular shuttling
In molecular shuttles, a ring molecule is threaded onto a linear molecular strand and can move between two portions of the strand, called stations, in response to external stimuli. Chemical stimuli, l...
phys.org
February 20, 2025 at 7:53 PM
A una molecula le "cuesta" lo mismo subir que bajar la barrera energética entre dos estados metaestables. @emiliomperezlab.bsky.social @3mlab.bsky.social lo observan por primera vez en nanomaquinas moleculares 👉
phys.org/news/2025-02...
phys.org/news/2025-02...
Reposted by Borja Ibarra
Ismael Plaza defended successfully his thesis "In Singulo characterization of the real-time kinetics of the human mitochondrial DNA replisome", directed by Prof Borja Ibarra @3mlab.bsky.social @imdeananociencia.bsky.social
🎓 Congratulations Doctor!
🎓 Congratulations Doctor!
April 2, 2025 at 8:02 AM
Ismael Plaza defended successfully his thesis "In Singulo characterization of the real-time kinetics of the human mitochondrial DNA replisome", directed by Prof Borja Ibarra @3mlab.bsky.social @imdeananociencia.bsky.social
🎓 Congratulations Doctor!
🎓 Congratulations Doctor!
Reposted by Borja Ibarra
Paper with @emiliomperezlab.bsky.social and @3mlab.bsky.social et al. in print! Experimental energy landscape calculated (journals.aps.org/pre/abstract...) from the Onsager-Machlup approach for systems in mechanical but not necessarily thermodynamic equilibrium.
www.cell.com/chem/fulltex...
www.cell.com/chem/fulltex...
Transition-path times of individual molecular shuttles under mechanical equilibrium show symmetry
This study explores microscopic reversibility to understand the operation of molecular
devices.
www.cell.com
February 11, 2025 at 4:03 PM
Paper with @emiliomperezlab.bsky.social and @3mlab.bsky.social et al. in print! Experimental energy landscape calculated (journals.aps.org/pre/abstract...) from the Onsager-Machlup approach for systems in mechanical but not necessarily thermodynamic equilibrium.
www.cell.com/chem/fulltex...
www.cell.com/chem/fulltex...
Reposted by Borja Ibarra
Fresh off the press! Read our latest article with @3mlab.bsky.social and @deanast.bsky.social just out at Chem @cellpress.bsky.social!
www.sciencedirect.com/science/arti...
#ChemSky #SciSky #PhySky #molecularmachines
1/5
www.sciencedirect.com/science/arti...
#ChemSky #SciSky #PhySky #molecularmachines
1/5
Transition-path times of individual molecular shuttles under mechanical equilibrium show symmetry
Measuring individual trajectories during the operation of synthetic devices is crucial for a thorough understanding of this operation. Here, we use op…
www.sciencedirect.com
February 11, 2025 at 4:23 PM
Fresh off the press! Read our latest article with @3mlab.bsky.social and @deanast.bsky.social just out at Chem @cellpress.bsky.social!
www.sciencedirect.com/science/arti...
#ChemSky #SciSky #PhySky #molecularmachines
1/5
www.sciencedirect.com/science/arti...
#ChemSky #SciSky #PhySky #molecularmachines
1/5
We are hiring!
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
February 7, 2025 at 3:28 PM
We are hiring!
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
Reposted by Borja Ibarra
🔴⚠CNIO-CaixaResearch Frontiers Meetings: Machines acting on DNA and RNA, a molecular mechanistic perspective.
📆May 28-30th
👥 @oscarllorca.bsky.social, @rfleiro.bsky.social and @nogaleslab.bsky.social.
🔗https://www.cnio.es/eventos/machines-acting-on-dna-and-rna-a-molecular-mechanistic-perspective/
📆May 28-30th
👥 @oscarllorca.bsky.social, @rfleiro.bsky.social and @nogaleslab.bsky.social.
🔗https://www.cnio.es/eventos/machines-acting-on-dna-and-rna-a-molecular-mechanistic-perspective/
February 5, 2025 at 4:03 PM
🔴⚠CNIO-CaixaResearch Frontiers Meetings: Machines acting on DNA and RNA, a molecular mechanistic perspective.
📆May 28-30th
👥 @oscarllorca.bsky.social, @rfleiro.bsky.social and @nogaleslab.bsky.social.
🔗https://www.cnio.es/eventos/machines-acting-on-dna-and-rna-a-molecular-mechanistic-perspective/
📆May 28-30th
👥 @oscarllorca.bsky.social, @rfleiro.bsky.social and @nogaleslab.bsky.social.
🔗https://www.cnio.es/eventos/machines-acting-on-dna-and-rna-a-molecular-mechanistic-perspective/
Reposted by Borja Ibarra
Single molecule approaches across the central dogma! Genomics, imaging and theory! Very excited to host the first edition of Gene regulation, one molecule at a time this July @embl.org! Great lineup and many abstract selected talks!
📣 #EMBLSingleMolecule is open for registrations!
Our aim is to catalyse the emergence of a new generation of mechanistic models of the regulation of genes across each steps of the central dogma. 🧬🔍
👉🏼 s.embl.org/grg25-01-bl
📅 15 – 18 July 2025
📜 Submit your abstract by 8 April!
Our aim is to catalyse the emergence of a new generation of mechanistic models of the regulation of genes across each steps of the central dogma. 🧬🔍
👉🏼 s.embl.org/grg25-01-bl
📅 15 – 18 July 2025
📜 Submit your abstract by 8 April!
January 15, 2025 at 1:11 PM
Single molecule approaches across the central dogma! Genomics, imaging and theory! Very excited to host the first edition of Gene regulation, one molecule at a time this July @embl.org! Great lineup and many abstract selected talks!
Reposted by Borja Ibarra
What a way to start 2025! Our review on the Known Unknowns of the Hsp90 Chaperone has been published!
Huge thanks to Laura Silbermann and Benjamin Vermeer for all of their efforts, and to @scisonja.bsky.social for the great collaboration :)
You can read it here:
elifesciences.org/articles/102...
Huge thanks to Laura Silbermann and Benjamin Vermeer for all of their efforts, and to @scisonja.bsky.social for the great collaboration :)
You can read it here:
elifesciences.org/articles/102...
The known unknowns of the Hsp90 chaperone
An exploration of the unanswered questions in how the molecular chaperone Hsp90 supports protein homeostasis, and how single-molecule techniques could drive future breakthroughs in answering them.
elifesciences.org
January 1, 2025 at 9:35 AM
What a way to start 2025! Our review on the Known Unknowns of the Hsp90 Chaperone has been published!
Huge thanks to Laura Silbermann and Benjamin Vermeer for all of their efforts, and to @scisonja.bsky.social for the great collaboration :)
You can read it here:
elifesciences.org/articles/102...
Huge thanks to Laura Silbermann and Benjamin Vermeer for all of their efforts, and to @scisonja.bsky.social for the great collaboration :)
You can read it here:
elifesciences.org/articles/102...
Reposted by Borja Ibarra
First paper of our lab today @natureportfolio.bsky.social by Nussi!
We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!
@embl.org #RNAbiology #RNASky
t.co/a24Xxcxdo0
We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!
@embl.org #RNAbiology #RNASky
t.co/a24Xxcxdo0
December 4, 2024 at 8:53 PM
First paper of our lab today @natureportfolio.bsky.social by Nussi!
We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!
@embl.org #RNAbiology #RNASky
t.co/a24Xxcxdo0
We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!
@embl.org #RNAbiology #RNASky
t.co/a24Xxcxdo0