Afshin Samali
@afshinsamali.bsky.social
ER Stress, Unfolded Protein Response, Cancer Biology
Pinned
🎓 Want to do a PhD in cancer biology?
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 [email protected]
#CancerResearch #TNBC #MolecularBiology #PhDPositions
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 [email protected]
#CancerResearch #TNBC #MolecularBiology #PhDPositions
NF-κB is a central regulator of hypoxia-induced gene expression | EMBO reports www.embopress.org/doi/full/10....
NF-κB is a central regulator of hypoxia-induced gene expression | EMBO reports
imageimageHypoxia induces a specific NF-κB-dependent gene signature across multiple cell systems.
NF-κB is required for over 60% of gene repression occurring in response to hypoxia,
controlling oxidat...
www.embopress.org
November 26, 2025 at 7:40 PM
NF-κB is a central regulator of hypoxia-induced gene expression | EMBO reports www.embopress.org/doi/full/10....
Reposted by Afshin Samali
The programme is designed to invest in research equipment from routine equipment that is used in higher education institutions to more advanced equipment that can be shared across several institutions as well as being accessible to external users.
€750m ‘Inspire’ investment aims to transform Ireland’s research infrastructure
Today saw the lunch of a new €750m investment fund to ensure Ireland's higher education sector has the equipment and infrastructure required to compete globally.
www.siliconrepublic.com
November 26, 2025 at 9:03 AM
The programme is designed to invest in research equipment from routine equipment that is used in higher education institutions to more advanced equipment that can be shared across several institutions as well as being accessible to external users.
Reposted by Afshin Samali
Reposted by Afshin Samali
🎓 Want to do a PhD in cancer biology?
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 [email protected]
#CancerResearch #TNBC #MolecularBiology #PhDPositions
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 [email protected]
#CancerResearch #TNBC #MolecularBiology #PhDPositions
November 20, 2025 at 2:16 PM
🎓 Want to do a PhD in cancer biology?
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 [email protected]
#CancerResearch #TNBC #MolecularBiology #PhDPositions
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 [email protected]
#CancerResearch #TNBC #MolecularBiology #PhDPositions
🎓 Want to do a PhD in cancer biology?
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 [email protected]
#CancerResearch #TNBC #MolecularBiology #PhDPositions
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 [email protected]
#CancerResearch #TNBC #MolecularBiology #PhDPositions
November 20, 2025 at 2:16 PM
🎓 Want to do a PhD in cancer biology?
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 [email protected]
#CancerResearch #TNBC #MolecularBiology #PhDPositions
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 [email protected]
#CancerResearch #TNBC #MolecularBiology #PhDPositions
Reposted by Afshin Samali
🔬 Experience Research Life at Cambridge!
Applications are now open for the 2026 Experience Postgrad Life Sciences Programme. Gain hands-on lab experience with an 8-week summer placement, in partnership with @corpuscambridge.bsky.social!
🔗 www.exppg.lifesci.cam.ac.uk
#SummerPlacement #Cambridge
Applications are now open for the 2026 Experience Postgrad Life Sciences Programme. Gain hands-on lab experience with an 8-week summer placement, in partnership with @corpuscambridge.bsky.social!
🔗 www.exppg.lifesci.cam.ac.uk
#SummerPlacement #Cambridge
November 13, 2025 at 10:52 AM
🔬 Experience Research Life at Cambridge!
Applications are now open for the 2026 Experience Postgrad Life Sciences Programme. Gain hands-on lab experience with an 8-week summer placement, in partnership with @corpuscambridge.bsky.social!
🔗 www.exppg.lifesci.cam.ac.uk
#SummerPlacement #Cambridge
Applications are now open for the 2026 Experience Postgrad Life Sciences Programme. Gain hands-on lab experience with an 8-week summer placement, in partnership with @corpuscambridge.bsky.social!
🔗 www.exppg.lifesci.cam.ac.uk
#SummerPlacement #Cambridge
Reposted by Afshin Samali
First-ever atlas of brain development shows how stem cells turn into neurons
There are 6 excellent human brain development papers in Nature - www.nature.com/articles/d41... Check them out!
There are 6 excellent human brain development papers in Nature - www.nature.com/articles/d41... Check them out!
November 11, 2025 at 12:13 AM
First-ever atlas of brain development shows how stem cells turn into neurons
There are 6 excellent human brain development papers in Nature - www.nature.com/articles/d41... Check them out!
There are 6 excellent human brain development papers in Nature - www.nature.com/articles/d41... Check them out!
Breastfeeding boosts anticancer immunity through recruitment of CD8+ T cells
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Breastfeeding boosts immune cells that protect against breast cancer
The protective, long-lived T cells can persist for decades after a woman gives birth.
www.nature.com
October 22, 2025 at 8:17 AM
Breastfeeding boosts anticancer immunity through recruitment of CD8+ T cells
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Afshin Samali
An analysis of patient records suggests that mRNA covid-19 vaccines boost the immune response to cancerous tumours when given soon after people start a type of immunotherapy, extending their lives
mRNA covid vaccines spark immune response that may aid cancer survival
An analysis of patient records suggests that mRNA covid-19 vaccines boost the immune response to cancerous tumours when given soon after people start a type of immunotherapy, extending their lives
www.newscientist.com
October 20, 2025 at 4:44 PM
An analysis of patient records suggests that mRNA covid-19 vaccines boost the immune response to cancerous tumours when given soon after people start a type of immunotherapy, extending their lives
Reposted by Afshin Samali
Scientists are designing mRNA vaccines to produce virus-like nanoparticles, which should lead to a more robust immune response with even fewer side effects than either of these immunisation approaches on their own
Why the next generation of mRNA vaccines is set to be even better
www.newscientist.com
October 20, 2025 at 6:45 PM
Scientists are designing mRNA vaccines to produce virus-like nanoparticles, which should lead to a more robust immune response with even fewer side effects than either of these immunisation approaches on their own
A new blood test has been been approved by FDA to assist in diagnosing Alzheimer’s disease.
go.nature.com/47b4hIp
go.nature.com/47b4hIp
Blood tests are now approved for Alzheimer’s: how accurate are they?
A second blood test has been been approved by the US Food and Drug Administration to assist in diagnosing Alzheimer’s disease. Will these tests change how cognitive decline is measured?
go.nature.com
October 18, 2025 at 12:04 AM
A new blood test has been been approved by FDA to assist in diagnosing Alzheimer’s disease.
go.nature.com/47b4hIp
go.nature.com/47b4hIp
Reposted by Afshin Samali
A new blood test to aid with the diagnosis of Alzheimer’s disease has been approved by the US FDA
go.nature.com/47b4hIp
go.nature.com/47b4hIp
Blood tests are now approved for Alzheimer’s: how accurate are they?
A second blood test has been been approved by the US Food and Drug Administration to assist in diagnosing Alzheimer’s disease. Will these tests change how cognitive decline is measured?
go.nature.com
October 17, 2025 at 1:25 PM
A new blood test to aid with the diagnosis of Alzheimer’s disease has been approved by the US FDA
go.nature.com/47b4hIp
go.nature.com/47b4hIp
Reposted by Afshin Samali
Dissecting Branch-Specific Unfolded Protein Response Activation in Drug-Tolerant BRAF-Mutant Melanoma using Data-Independent Acquisition Mass Spectrometry - Molecular & Cellular Proteomics www.mcponline.org/article/S153...
Dissecting Branch-Specific Unfolded Protein Response Activation in Drug-Tolerant BRAF-Mutant Melanoma using Data-Independent Acquisition Mass Spectrometry
Cells rely on the Unfolded Protein Response (UPR) to maintain ER protein homeostasis
(proteostasis) when faced with elevated levels of misfolded and aggregated proteins.
The UPR is comprised of three ...
www.mcponline.org
July 25, 2025 at 5:15 PM
Dissecting Branch-Specific Unfolded Protein Response Activation in Drug-Tolerant BRAF-Mutant Melanoma using Data-Independent Acquisition Mass Spectrometry - Molecular & Cellular Proteomics www.mcponline.org/article/S153...
Obesity gene shields against heart disease
www.nature.com/articles/d41...
www.nature.com/articles/d41...
This gene causes obesity — and shields against heart disease
People with certain forms of the MC4R gene have lower cholesterol levels than do other individuals with a high body-mass index.
www.nature.com
October 17, 2025 at 8:34 PM
Obesity gene shields against heart disease
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Afshin Samali
The countdown to Science Week 2025 is on 🔬🗓️
Supported by Research Ireland, Science Week is marking its 30th anniversary this year!
Festival and event details are coming soon! Stay tuned and keep an eye on www.scienceweek.ie for the latest updates.
#ScienceWeek #ThenTodayTomorrow
Supported by Research Ireland, Science Week is marking its 30th anniversary this year!
Festival and event details are coming soon! Stay tuned and keep an eye on www.scienceweek.ie for the latest updates.
#ScienceWeek #ThenTodayTomorrow
October 13, 2025 at 12:51 PM
The countdown to Science Week 2025 is on 🔬🗓️
Supported by Research Ireland, Science Week is marking its 30th anniversary this year!
Festival and event details are coming soon! Stay tuned and keep an eye on www.scienceweek.ie for the latest updates.
#ScienceWeek #ThenTodayTomorrow
Supported by Research Ireland, Science Week is marking its 30th anniversary this year!
Festival and event details are coming soon! Stay tuned and keep an eye on www.scienceweek.ie for the latest updates.
#ScienceWeek #ThenTodayTomorrow
How #immigration drives winning #science - "Talent can be born anywhere, but opportunities are not" www.nature.com/articles/d41...
More than 30% of this century’s science Nobel prizewinners immigrated: see their journeys
The most common destination for eventual Nobel laureates in physics, chemistry and medicine since 2000 is the United States, Nature has found.
www.nature.com
October 11, 2025 at 11:33 AM
How #immigration drives winning #science - "Talent can be born anywhere, but opportunities are not" www.nature.com/articles/d41...
Reposted by Afshin Samali
Since 2019, POI has worked to accelerate the development of personalised cancer therapy & diagnostic options. Today we begin Stage 2 of our journey, building on strong foundations and expanding our collaborations to drive innovation & shape the future of cancer care.
October 8, 2025 at 3:11 PM
Since 2019, POI has worked to accelerate the development of personalised cancer therapy & diagnostic options. Today we begin Stage 2 of our journey, building on strong foundations and expanding our collaborations to drive innovation & shape the future of cancer care.
Reposted by Afshin Samali
Minister James Lawless has launched Phase 2 of Ireland’s leading and largest ever cancer research programme, @precisiononcire.bsky.social. The programme is co-funded through Research Ireland, industry and the not-for-profit sector. Read more: www.researchireland.ie/news/precision-oncology-ireland/
October 8, 2025 at 3:04 PM
Minister James Lawless has launched Phase 2 of Ireland’s leading and largest ever cancer research programme, @precisiononcire.bsky.social. The programme is co-funded through Research Ireland, industry and the not-for-profit sector. Read more: www.researchireland.ie/news/precision-oncology-ireland/
Reposted by Afshin Samali
Since 2019, POI has driven huge research impacts, from biological insights to training the next generation of researchers. On #WorldCancerResearchDay, we’re proud to share our new brochure, developed with science journalist Claire O'Connell, highlighting these achievements
tinyurl.com/jnhs762h
tinyurl.com/jnhs762h
September 24, 2025 at 12:20 PM
Since 2019, POI has driven huge research impacts, from biological insights to training the next generation of researchers. On #WorldCancerResearchDay, we’re proud to share our new brochure, developed with science journalist Claire O'Connell, highlighting these achievements
tinyurl.com/jnhs762h
tinyurl.com/jnhs762h
No strong evidence for autism-Tylenol link. www.nature.com/articles/d41...
Trump links autism and Tylenol: is there any truth to it?
The US president repeatedly advised people, “Don't take Tylenol,” but scientists say that strong evidence between the medication and autism is lacking.
www.nature.com
September 24, 2025 at 12:24 PM
No strong evidence for autism-Tylenol link. www.nature.com/articles/d41...
Five problems plaguing publishing in the life sciences—and one common cause - Wright - 2024 - FEBS Letters - Wiley Online Library febs.onlinelibrary.wiley.com/doi/10.1002/...
FEBS Press
Although publication in scholarly peer-reviewed journals remains the gold standard for communication of findings in the life sciences, the gold has been debased by various impurities. Here, I discuss...
febs.onlinelibrary.wiley.com
September 17, 2025 at 11:04 AM
Five problems plaguing publishing in the life sciences—and one common cause - Wright - 2024 - FEBS Letters - Wiley Online Library febs.onlinelibrary.wiley.com/doi/10.1002/...
Samali Foundation will be honoured for its work at the Mayo Irish Diaspora Society 2025 Awards ceremony, tomorrow 13 September, #Castlebar #Mayo.
We are delighted be be amongst nine individuals and groups to be honoured at the Mayo Irish Diaspora Society 2025 Awards ceremony, tomorrow 13 September, #Castlebar #Mayo.
www.con-telegraph.ie/2025/08/18/m...
www.con-telegraph.ie/2025/08/18/m...
www.con-telegraph.ie/2025/08/18/m...
www.con-telegraph.ie/2025/08/18/m...
Mayo Irish Diaspora Society announces awards recipients | Connaught Telegraph
NINE individuals and groups are to be honoured at the Mayo Irish Diaspora Society 2025 Awards ceremony next month.
www.con-telegraph.ie
September 12, 2025 at 5:01 PM
Samali Foundation will be honoured for its work at the Mayo Irish Diaspora Society 2025 Awards ceremony, tomorrow 13 September, #Castlebar #Mayo.
Reposted by Afshin Samali
Excited to share our @narjournal.bsky.social work on a trackable trinuclear platinum complex for breast cancer therapy: doi.org/10.1093/nar/... 🧬
With @raphael-depaiva.bsky.social @afshinsamali.bsky.social @alicepyne.bsky.social @westerlundlab.bsky.social @researchireland.ie @dcuresearch.bsky.social
With @raphael-depaiva.bsky.social @afshinsamali.bsky.social @alicepyne.bsky.social @westerlundlab.bsky.social @researchireland.ie @dcuresearch.bsky.social
July 17, 2025 at 5:11 PM
Excited to share our @narjournal.bsky.social work on a trackable trinuclear platinum complex for breast cancer therapy: doi.org/10.1093/nar/... 🧬
With @raphael-depaiva.bsky.social @afshinsamali.bsky.social @alicepyne.bsky.social @westerlundlab.bsky.social @researchireland.ie @dcuresearch.bsky.social
With @raphael-depaiva.bsky.social @afshinsamali.bsky.social @alicepyne.bsky.social @westerlundlab.bsky.social @researchireland.ie @dcuresearch.bsky.social
It was lovely to interview with @sorchapollak.bsky.social @irishtimes.com regarding @samalifoundation.bsky.social
#Education #Refugee
www.irishtimes.com/ireland/soci...
#Education #Refugee
www.irishtimes.com/ireland/soci...
Galway hotel fire ‘pulled our community together to help other newcomers’, says professor
Cancer specialist recalls 2023 incident as he launches foundation to help refugees and asylum seekers access education
www.irishtimes.com
June 23, 2025 at 11:12 AM
It was lovely to interview with @sorchapollak.bsky.social @irishtimes.com regarding @samalifoundation.bsky.social
#Education #Refugee
www.irishtimes.com/ireland/soci...
#Education #Refugee
www.irishtimes.com/ireland/soci...