Anish Simhal
@aksimhal.bsky.social
Postdoctoral Fellow at @MSKCancerCenter Mathematical Oncology Initiative. Researching network science, genomics, oncology. Previously @DukeU, @UVA
Pinned
Anish Simhal
@aksimhal.bsky.social
· Feb 21
1/ 🚨New research alert! 🚨Our study in Blood Cancer shows that high WEE1 expression is an independent predictor of poor survival in multiple myeloma, with @joedeasy.bsky.social, @malinhultcrantz.bsky.social, @szusmani.bsky.social, and the rest of the @mskcancercenter.bsky.social team! 🧵👇#MyelomaSky
Excited to share Dr. Elkin's NetFlow manuscript — a framework for constructing interpretable graph representations of high-dimensional biomedical data. It captures both clustering and continuous variation to reveal biologically meaningful structure. #AI #Oncology #Bioinformatics
NetFlow: A Framework to Explore Topological Representations of High-Dimensional Biomedical Data https://www.biorxiv.org/content/10.1101/2025.10.24.683878v1
October 29, 2025 at 1:45 PM
Excited to share Dr. Elkin's NetFlow manuscript — a framework for constructing interpretable graph representations of high-dimensional biomedical data. It captures both clustering and continuous variation to reveal biologically meaningful structure. #AI #Oncology #Bioinformatics
Reposted by Anish Simhal
(1/2) Lung cancer can co-opt genes that normally help a fetus develop and evade the mother’s immune system, according to research from Dr. Jung Hun Oh.
And while these pregnancy-specific glycoproteins (PSGs) can get activated in the cancers of both men & women, female patients had poorer outcomes.
And while these pregnancy-specific glycoproteins (PSGs) can get activated in the cancers of both men & women, female patients had poorer outcomes.
Pregnancy-Related Proteins in Tumors Linked to Worse Survival in Female Lung Cancer Patients
Lung cancer co-opts genes that normally help a fetus develop and evade the mother’s immune system — leading to poorer outcomes in female patients, an MSK research team has found.
bit.ly
June 16, 2025 at 3:10 PM
(1/2) Lung cancer can co-opt genes that normally help a fetus develop and evade the mother’s immune system, according to research from Dr. Jung Hun Oh.
And while these pregnancy-specific glycoproteins (PSGs) can get activated in the cancers of both men & women, female patients had poorer outcomes.
And while these pregnancy-specific glycoproteins (PSGs) can get activated in the cancers of both men & women, female patients had poorer outcomes.
🚀 Just published in Bioinformatics! Introducing ORCO: Ollivier-Ricci Curvature-Omics, a python package for analyzing robustness in biological systems. A 🧵 on what it is, why it matters, and how you can use it. With @joedeasy.bsky.social and the great team at @mskcancercenter.bsky.social
March 14, 2025 at 3:20 PM
🚀 Just published in Bioinformatics! Introducing ORCO: Ollivier-Ricci Curvature-Omics, a python package for analyzing robustness in biological systems. A 🧵 on what it is, why it matters, and how you can use it. With @joedeasy.bsky.social and the great team at @mskcancercenter.bsky.social
Reposted by Anish Simhal
ORCO: Ollivier-Ricci Curvature-Omics: an unsupervised method for analyzing robustness in biological systems https://www.biorxiv.org/content/10.1101/2024.10.06.616915v1
ORCO: Ollivier-Ricci Curvature-Omics: an unsupervised method for analyzing robustness in biological systems https://www.biorxiv.org/content/10.1101/2024.10.06.616915v1
Although recent advanced sequencing technologies have improved the resolution of genomic and proteom
www.biorxiv.org
October 11, 2024 at 10:46 PM
ORCO: Ollivier-Ricci Curvature-Omics: an unsupervised method for analyzing robustness in biological systems https://www.biorxiv.org/content/10.1101/2024.10.06.616915v1
1/ 🚨New research alert! 🚨Our study in Blood Cancer shows that high WEE1 expression is an independent predictor of poor survival in multiple myeloma, with @joedeasy.bsky.social, @malinhultcrantz.bsky.social, @szusmani.bsky.social, and the rest of the @mskcancercenter.bsky.social team! 🧵👇#MyelomaSky
February 21, 2025 at 7:36 PM
1/ 🚨New research alert! 🚨Our study in Blood Cancer shows that high WEE1 expression is an independent predictor of poor survival in multiple myeloma, with @joedeasy.bsky.social, @malinhultcrantz.bsky.social, @szusmani.bsky.social, and the rest of the @mskcancercenter.bsky.social team! 🧵👇#MyelomaSky