Alexander V. Veselov 😷🎮
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alexxxmd.bsky.social
Alexander V. Veselov 😷🎮
@alexxxmd.bsky.social
1K followers 240 following 460 posts
😷 M.D., Ph.D.
🦠 Institute of Antimicrobial Chemotherapy, Smolensk State Medical University, Russia
🙃 Opinions and spelling mistakes are my own
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alexxxmd.bsky.social
Carbapenemase-producing Enterobacterales in the hospital water environment: a narrative review
Léna Sleiman, et al.
CMI, 2025.
www.clinicalmicrobiologyandinfection.org/article/S119...
December 13, 2025 at 8:28 AM
alexxxmd.bsky.social
Antibacterial Pharmacokinetics in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation (ECMO): A Systematic Review of Population Pharmacokinetic Studies. 
Ren, C., Huang, F., Cheng, V. et al. 
Clin Pharmacokinet (2025).
doi.org/10.1007/s402...
December 13, 2025 at 8:28 AM
alexxxmd.bsky.social
#GSK
12 December 2025
GSK’s RSV vaccine, Arexvy, receives positive CHMP opinion for all adults 18 years and older

11 December 2025
Blujepa (gepotidacin) approved by US FDA as oral option for treatment of uncomplicated urogenital gonorrhoea (uGC)
December 12, 2025 at 10:16 AM
alexxxmd.bsky.social
Protective role of Haemophilus influenzae in Streptococcus pneumoniae-induced epithelium injury.
Emi Tanaka, et al.
Microbial Pathogenesis, 2025.
doi.org/10.1016/j.mi...
December 12, 2025 at 9:35 AM
alexxxmd.bsky.social
Seven versus Fourteen Days of Antibiotics for Gram-Negative Bacteremia from a Urinary Tract Source: a Systematic Review and Meta-analysis.
Luna, G., Rodriguez, A., Igbonagwam, C. et al.
Infect Dis Ther (2025).
doi.org/10.1007/s401...
Seven versus Fourteen Days of Antibiotics for Gram-Negative Bacteremia from a Urinary Tract Source: a Systematic Review and Meta-analysis - Infectious Diseases and Therapy
Introduction The optimal duration of antibiotic therapy for Gram-negative bacteremia sourced from urinary tract infections (UTI) remains uncertain. We performed a systematic review and meta-analysis c...
doi.org
December 12, 2025 at 9:07 AM
alexxxmd.bsky.social
Zoliflodacin vs ceftriaxone plus azithromycin for treatment of uncomplicated urogenital gonorrhoea: an international, randomised, controlled, open-label, phase 3, non-inferiority clinical trial
Alison Luckey et al.
Lancet, 2025.
doi.org/10.1016/S014...
Redirecting
doi.org
December 12, 2025 at 6:33 AM
alexxxmd.bsky.social
Interpretive agreement of susceptibility between BMD and DDM for cefiderocol, using CLSI, EUCASST and FDA criteria.
Yu-Tzu Lin et al.
Journal of Clinical Microbiology, 2025
journals.asm.org/doi/10.1128/...
ORCID
orcid.org
December 11, 2025 at 7:53 AM
alexxxmd.bsky.social
Genetic Determinants Associated With the Biofilm Formation Impairment in Pseudomonas aeruginosa Clinical Isolates - Vvedenskii - 2025 - MicrobiologyOpen - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
Genetic Determinants Associated With the Biofilm Formation Impairment in Pseudomonas aeruginosa Clinical Isolates
Numerous studies have reported biofilm formation impairment in Pseudomonas aeruginosa clinical isolates, however, the genetic basis of this phenomenon remains largely unexplored. In this study, we ai....
onlinelibrary.wiley.com
December 11, 2025 at 7:48 AM
alexxxmd.bsky.social
News from MSD. Thats it, thats all. 💀
#MSD #Merk
December 10, 2025 at 3:57 PM
alexxxmd.bsky.social
Current Management Strategies of Difficult-to-Treat Resistant Pseudomonas aeruginosa Infections.
Juan P Horcajada, et al.
Infect Dis Clin North Am. 2025 Dec 8:S0891-5520(25)00095-9.
doi: 10.1016/j.idc.2025.11.001. Online ahead of print.
December 10, 2025 at 10:31 AM
alexxxmd.bsky.social
Precision Immunotherapy to Improve Sepsis Outcomes - The ImmunoSep Randomized Clinical Trial
Evangelos J. Giamarellos-Bourboulis, et al.
JAMA, 2025
jamanetwork.com/journals/jam...
Precision Immunotherapy to Improve Sepsis Outcomes
This randomized trial assesses whether precision immunotherapy tailored to macrophage activation–like syndrome or sepsis-induced immunoparalysis improved organ dysfunction compared with placebo among ...
jamanetwork.com
December 9, 2025 at 11:18 AM
alexxxmd.bsky.social
Current standard of care for septic shock.
Delaney, A., Borges-Sa, M., Chew, M.S. et al.
Intensive Care Med (2025).
doi.org/10.1007/s001...
Current standard of care for septic shock - Intensive Care Medicine
Sepsis is a syndrome of life-threatening organ dysfunction that results from dysregulated host response to infection, with septic shock defined as persistent hypotension despite fluid resuscitation, a...
doi.org
December 8, 2025 at 6:47 PM
alexxxmd.bsky.social
The Importance of Early Mycological Clearance of Uncomplicated Candidaemia and Its Implications for Clinical Practice - Cornely - 2025 - Mycoses - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
The Importance of Early Mycological Clearance of Uncomplicated Candidaemia and Its Implications for Clinical Practice
Invasive candidiasis is a life-threatening infection associated with high morbidity, mortality and healthcare costs in both general and critical care settings. Timely diagnosis and adequate antifunga....
onlinelibrary.wiley.com
December 5, 2025 at 7:19 PM
alexxxmd.bsky.social
Navigating the Challenges in Staphylococcus aureus Bloodstream Infection: A Practical Guide to Management.
Hadar Mudrik-Zohar, et al.
Infectious Disease Clinics of North America, 2025.
doi.org/10.1016/j.id...
Redirecting
doi.org
December 5, 2025 at 10:59 AM
Reposted by Alexander V. Veselov 😷🎮
abalkina.bsky.social
We see a new phenomenon. Fake authors in papers with hundreds of citations. Papers are easy to produce by ChatGPT. Even if a paper is retracted, no punishment to the real authors, but citations still count. Today's puzzle is about a similar case papermills.tilda.ws/2025advent4
Advent2025 4
papermills.tilda.ws
December 4, 2025 at 8:45 AM
Reposted by Alexander V. Veselov 😷🎮
olivercornely.bsky.social
New 2024 AGIHO/DGHO guideline on CNS infections in hematologic & oncologic patients: NGS/ddPCR, ciHHV-6, refined steroid use, new viral & fungal treatment insights. Essential update for clinicians.
www.sciencedirect.com/science/arti...

#InfectiousDiseases #Hematology #Oncology
CNS infections in patients with hematological or oncological diseases (including cellular therapies) – 2024 update of the guideline of the Infectious Diseases Working Party (AGIHO) of the German Socie...
Infections of the central nervous system (CNS) occur in up to 15 % of patients with hematological or oncological diseases (HOD), particularly in high-…
www.sciencedirect.com
December 4, 2025 at 9:21 AM
alexxxmd.bsky.social
In vitro exebacase (CF-301) activity against methicillin-susceptible or methicillin-resistant Staphylococcus aureus and coagulase-negative staphylococci strains isolated from patients with infective endocarditis
María-Alexandra Cañas, et al.
JAC 2025
doi.org/10.1093/jac/...
In vitro exebacase (CF-301) activity against methicillin-susceptible or methicillin-resistant Staphylococcus aureus and coagulase-negative staphylococci strains isolated from patients with infective e...
AbstractBackground. Infective endocarditis (IE) is a severe infection mainly caused by Staphylococcus aureus, Enterococcus faecalis and viridans streptococ
doi.org
December 4, 2025 at 12:02 PM
Reposted by Alexander V. Veselov 😷🎮
enirenberg.bsky.social
The last 12 FDA commissioners did not mince their words (to the extent that one can do that in the context of an academic medical journal):
www.nejm.org/doi/full/10....
A Threat to Evidence-Based Vaccine Policy and Public Health Security at the FDA | NEJM
Twelve former commissioners of the FDA express concern that the agency’s recent moves will undermine a regulatory model designed to ensure vaccine safety, effectiveness, and availability.
www.nejm.org
December 3, 2025 at 10:21 PM
alexxxmd.bsky.social
Candida auris: host interactions, antifungal drug resistance, and diagnostics.
Anuradha Chowdhary, et al.
Microbiology and Molecular Biology Reviews
doi.org/10.1128/mmbr...
Candida auris: host interactions, antifungal drug resistance, and diagnostics | Microbiology and Molecular Biology Reviews
SUMMARYInvasive fungal infections affect approximately 6.5 million people every year. These infections are frequently associated with high mortality rates, often exceeding 50%, even with antifungal th...
doi.org
December 4, 2025 at 8:39 AM
alexxxmd.bsky.social
Syphilis - A Review
Franco J. Chevalier, et al.
JAMA 2025;334;(21):1927-1940.
jamanetwork.com/journals/jam...
Syphilis: A Review
This review summarizes the epidemiology, clinical manifestations, staging, and diagnosis of syphilis.
jamanetwork.com
December 2, 2025 at 7:22 PM
alexxxmd.bsky.social
The undiscovered natural product potential of Actinomycetes.
Caraballo-Rodríguez, A.M., Cumsille, A., Magyari, S. et al.
J Antibiot (2025).
doi.org/10.1038/s414...
The undiscovered natural product potential of Actinomycetes - The Journal of Antibiotics
The Journal of Antibiotics - The undiscovered natural product potential of Actinomycetes
doi.org
December 2, 2025 at 7:11 PM
alexxxmd.bsky.social
An Emerging Infectious Yeast to Watch: Cryptococcus gattii Species Complex
Samantha N. Peltak and Tomoko Y. Steen
J. Fungi 2025, 11(12), 858;
doi.org/10.3390/jof1...
doi.org
December 2, 2025 at 3:19 PM
alexxxmd.bsky.social
Narrative review on microbiota and sepsis: the host’s betrayal?
Guarino, M., Di Ciaula, A., Portincasa, P. et al.
Intern Emerg Med (2025).
doi.org/10.1007/s117...
Narrative review on microbiota and sepsis: the host’s betrayal? - Internal and Emergency Medicine
Sepsis remains a leading cause of morbidity and mortality worldwide. Increasing evidence suggests that the gut microbiota, long considered a “less relevant” to human body health, it plays a crucial ro...
doi.org
December 2, 2025 at 3:13 PM
alexxxmd.bsky.social
Temporal robustness of biomarker-based classification algorithms for sepsis.
Rademaker, E., van Amstel, R.B.E., el Bouhaddani, S. et al.
Intensive Care Med (2025).
doi.org/10.1007/s001...
Temporal robustness of biomarker-based classification algorithms for sepsis - Intensive Care Medicine
Purpose Heterogeneity of the host response in sepsis hampers development of effective treatments. Several immunobiologically distinct subphenotypes (or endotypes) have been identified using data-drive...
doi.org
December 1, 2025 at 5:29 PM
alexxxmd.bsky.social
Imagine you're writing a guide to antimicrobial therapy. To which class would it be more appropriate to classify ibrexafungerp? Triterpenoids? Fungerps? Or...?
December 1, 2025 at 9:53 AM