ALK Positive Australia Inc.
@alkpostitiveaust.bsky.social
44 followers 33 following 16 posts
A charity dedicated to support & research for ALK Positive Cancer patients in Australia.
Posts Media Videos Starter Packs
alkpostitiveaust.bsky.social
Our website got a glow-up!
Launching in the next few days — same mission, fresh new look.

Got feedback or ideas? Drop us a message here or email [email protected]
alkpostitiveaust.bsky.social
Sending deep gratitude & support from Down Under.
alkpostitiveaust.bsky.social
"WHAT IS IT REALLY LIKE TO LIVE WITH ALK ON TKI'S IN AUSTRALIA?"
Share your story in this important study. This is open to any Australian ALKie at Stage IIIB or IV on a TKI for more than 12 months. It will be an online interview for 30-60 minutes.
Email [email protected] to share your story.
alkpostitiveaust.bsky.social
- 36 Australians are diagnosed with lung cancer every day.
- Lung cancer is the leading cause of cancer death in Australia, but attracts less than 6% of cancer research funding.

Today we acknowledge those raising awareness & working towards better outcomes for lung cancer patients.
alkpostitiveaust.bsky.social
Our Chair Jon & Dep Chair Lisa with Prof Nick Pavlakis, Prof Ben Solomon & Prof Tom John at the @togaanz.bsky.social ASM - working together for better outcomes for ALK Positive patients.
alkpostitiveaust.bsky.social
We could not be prouder of our Dep Chair & friend Lisa Briggs - the recently announced recipient of the 2025 Jeannie Ferris Award. Bravo Lisa - thank you for all that you do. You are a force!
Reposted by ALK Positive Australia Inc.
togaanz.bsky.social
🤝 Eligibility: Projects must involve consumer representatives.

Get ready to apply and make an impact!

Let’s work together to drive real change.

Find out more > buff.ly/2Tv3YUR
alkpostitiveaust.bsky.social
The ALK+ Australia & TOGA Inspirational Research Grant applications are now open! We are proudly seeking innovative research that makes a real difference for people living with ALK-positive lung cancer. thoraciconcology.org.au/inspirationa...
alkpostitiveaust.bsky.social
This recent presentation on the ALK+ vaccine & current research being undertaken in the US is truly a MUST WATCH. It brings true hope. Thank you to everyone involved, we are cheering you on from Down Under!
youtu.be/GxrUsGIAFUs?...
Break Through Cancer on ALKtALK 6/1/25: updates on ALK vaccine & targeting minimal residual disease
YouTube video by ALK Positive Inc.
youtu.be
alkpostitiveaust.bsky.social
ALK+ Community - many businesses make notable donations to charities at this time of year, for tax benefits & to demonstrate corporate social responsibility. If you know a decision maker in a the corporate world please put forward our charity for their consideration. More Research = More Life.
alkpostitiveaust.bsky.social
A wonderful, inspiring initiative that provides the entire ALK+ world with hope. Thank you!
alkpostitiveaust.bsky.social
CALLING RESEARCHERS! The ALK Positive Australia & TOGA Inspirational Research Grant for ALK+ NSCLC is back. We are seeking innovative research that makes a real difference for people living with ALK-positive lung cancer.

Now is the time to prepare a proposal. Further information coming soon.
alkpostitiveaust.bsky.social
One of our favourite days of the year. Go Research!
togaanz.bsky.social
Happy International Clinical Trials Day! 🎉

Today, we celebrate the incredible impact of clinical trials in thoracic oncology and everyone involved.

#ClinicalTrialsDay #ICTD2025 #LungCancerResearch #ASPiRATION #ASPiRATION2L
Reposted by ALK Positive Australia Inc.
yvonnediaz.bsky.social
Promising signals from the ALEK-B ph 2 trial: combining alectinib w bevacizumab achieved 97.1% 12-mo PFS & median PFS of 39.6 months in ALK+ #NSCLC. Intracranial control also notably strong.

Could this combo help overcome resistance in more aggressive ALK variants?
#research #lungcancer
The article titled "Alectinib in combination with bevacizumab as first-line treatment in ALK-rearranged non-small cell lung cancer (ALEK-B): a single-arm, phase 2 trial" presents findings from a clinical study evaluating the efficacy and safety of combining alectinib, an ALK tyrosine kinase inhibitor, with bevacizumab, an anti-angiogenic agent, in treating advanced ALK-rearranged non-small cell lung cancer (NSCLC).
Nature

Here are five key takeaways from the study:

Enhanced Progression-Free Survival (PFS): The combination therapy achieved a 12-month PFS rate of 97.1% and a 36-month PFS rate of 64.2%, indicating a potential improvement over historical data for alectinib monotherapy. 
Nature

High Overall Response Rate (ORR): All 41 patients in the study responded to the treatment, with 87.8% achieving partial responses and 12.2% achieving complete responses, resulting in a 100% ORR. 
Nature

Intracranial Efficacy: The therapy demonstrated significant activity in the central nervous system, with a 36-month intracranial PFS rate of 87.8%, suggesting effectiveness in preventing or delaying brain metastases. 
Nature

Manageable Safety Profile: While 46.3% of patients experienced grade 3–4 adverse events, including proteinuria and hepatotoxicity, no fatal events were reported, and quality of life improved over the course of treatment. 
Nature

Need for Further Research: The promising results support the rationale for conducting randomized controlled trials to compare this combination therapy directly with existing standard treatments and to further assess its benefits and risks. 
Nature

These findings suggest that the combination of alectinib and bevacizumab may offer a potent first-line treatment option for patients with advanced ALK-rearranged NSCLC, warranting further investigation in larger, randomized studies
Reposted by ALK Positive Australia Inc.
togaanz.bsky.social
🎙️ Vaccines in Thoracic Oncology: The Next Frontier in Immunotherapy

Join Prof Tom John, Prof Ken O'Byrne and special guest Prof Georgina Long AO as they delve into technological advances spurred by COVID-19 vaccine development, promising results from recent melanoma and lung cancer vaccine trials
alkpostitiveaust.bsky.social
Our Chairperson Jon advocating for molecular testing for all lung cancer patients on the national news, and raising awareness for ALK Positive lung cancer. youtu.be/eoAT1mDrKnM
ALK Positive advocating for molecular testing for all lung cancer patients.
YouTube video by ALK Positive Australia
youtu.be
Reposted by ALK Positive Australia Inc.
alkpositive.bsky.social
We’re proud to have Dr. Ken Culver representing @ALK_Positive at #AACR25 in Chicago this week!

We’re also partnering with @AACR on a $130K, 2-year fellowship supporting ALK+ lung cancer research 🌍 — open globally!

Apply by May 15: www.aacr.org/grants/aacr-...
Reposted by ALK Positive Australia Inc.
alkpostitiveaust.bsky.social
Congratulations to all involved in this incredible initiative for LC patients.
alkpostitiveaust.bsky.social
A must watch for anyone interested in ALK+ Lung Cancer & the advances being made in personalising treatment plans & understanding the behaviour of this cancer. A/Prof Chin talks about her incredible research project (funded by the TOGA/ALK+ Australia Inspirational grant).
youtu.be/w9M-4M9fNT8