Alper Akay
@alperakay.bsky.social
1.6K followers
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220 posts
UKRI Future Leaders Fellow / Group Leader. RNA (epi)Genetics of C. elegans. Views are my own. Likes and re-posts are not necessarily for endorsement. www.theakaylab.com
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Guifeng Wei
@guifengwei.bsky.social
· Sep 9
m6A and the NEXT complex direct Xist RNA turnover and X-inactivation dynamics - Nature Structural & Molecular Biology
Wei et al. show that the primary function of m6A on the nuclear long noncoding RNA Xist, a master regulator of X inactivation, is to promote RNA degradation. Xist turnover is mediated by the nuclear e...
www.nature.com
Reposted by Alper Akay
Reposted by Alper Akay
Reposted by Alper Akay
Kusterlab
@kusterlab.bsky.social
· Sep 9
Peptide-RNA photo-crosslinks with tunable RNA chain map protein-RNA interfaces
Photo-crosslinking mass spectrometry enables the identification of protein-RNA interactions in living cells, pinpointing interaction interfaces at single-amino acid resolution. However, current isolat...
doi.org